- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Peripheral Artery Disease Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Workplace Health and Well-being
- Brain Tumor Detection and Classification
- Systemic Sclerosis and Related Diseases
- Sleep and Work-Related Fatigue
- Peripheral Neuropathies and Disorders
- Systemic Lupus Erythematosus Research
- Advanced X-ray and CT Imaging
- Multiple Sclerosis Research Studies
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
University of Calgary
2024-2025
Siriraj Hospital
2020-2025
Mahidol University
2020-2025
Background: Rapid, accurate diagnosis and characterization of carotid atherosclerosis can help prevent disabling strokes. Although plaques be identified on CT angiography (CTA), interpretation is challenging for frontline physicians. Quantification plaque volume/composition requires much manual effort. We developed tested a fully automated tool segmenting lumens delineating atherosclerotic plaque, distinguishing between calcific hypodense components. Methods: used 528 consecutive cases with...
Background and Aims: Machine learning models have shown promising potential for automated hemorrhage detection segmentation, alleviating highly time-consuming manual contouring facilitating rapid clinical diagnosis. External validation is essential to assess model generalizability performance across new dataset configurations. To this end, we externally validated a novel segmentation in an unseen randomized-controlled trial dataset. Methods: A architecture based on denoising diffusion...
Introduction: Intraventricular hematoma (IVH) occurs in approximately 40% of acute intracerebral hemorrhage (ICH) patients and is significantly associated with worse clinical outcomes. According to cerebrospinal fluid dynamics, some blood within the ventricles may circulate through subarachnoid spaces, leading its apparent “disappearance” on follow-up imaging. We aim investigate association between initial IVH involvement significant early ICH retraction at Methods: Data are from MCAHP...
Background We aim to comprehensively assess and compare the predictive performance of haematoma expansion (HE) scores in a homogeneous cohort acute intracerebral haemorrhage (ICH) patients. Methods Existing for predicting HE ICH patients were included categorised by imaging modality: non-contrast CT (NCCT), single-phase angiography (sCTA) multiphase CTA (mCTA). The was evaluated with c-statistic population consecutive adult admitted tertiary care centre Southern Alberta, Canada, between...
BACKGROUND: Early ischemic change and collateral extent are colinear with core volume (ICV). We investigated the relationship between a combined score using Alberta Stroke Program Computed Tomography Score multiphase computed tomography angiography (mCTA) extent, named mCTA-ACE score, on functional outcomes in endovascular therapy–treated patients. METHODS: performed post hoc analysis of subset patients from Alteplase Compared to Tenecteplase trial which was conducted December 2019 January...
Early ischemic changes on baseline imaging are commonly evaluated for acute stroke decision-making and prognostication.
The efficacy of mobile stroke units (MSUs) in improving acute ischemic (AIS) care developing countries is unknown. We compared performance measures and outcomes AIS patients between MSU usual care: emergency medical services (EMS) walk-in.We enrolled > 18 years age with an within 4.5 h after onset. Demographic data, types, time reperfusion therapies clinical were recorded. A favorable outcome was defined as a modified Rankin Scale (mRS) 0-2 at 3 months.A total 978 (MSU = 243, EMS 214,...
Background About 25% of patients with acute ischemic stroke have lacunar infarct on follow‐up imaging. In this secondary analysis from the AcT (Alteplase Compared With Tenecteplase) trial, we assessed if there is variation in safety or efficacy intravenous thrombolysis by type no visible occlusion. We also determined effect differed between tenecteplase and alteplase. Methods Results This a trial. Lacunar was defined as single, ≤15 mm, regions supplied perforating arterioles 24‐hour Outcomes...
Abstract Background Currently, there are limited data on the accuracy of available risk scores to predict stroke recurrence in Asian population. Method A single-center, retrospective cohort study was conducted among patients with acute ischemic during January 2014 - December 2018. Longitudinal three years follow-up these were collected and validated through both electronic manual chart review. The area under receiver-operating curve (AUROC) method or C-statistic calibration plot used...
Stroke is considered a vital public health issues on the global, Thailand including. has higher tendency for stroke and comes across working age numerically. This case control study was conducted to association between job stress stroke. The cases are twenty first-time patients within one-month period. controls people who have never admitted Pairmatched with gender, work characteristics used select samples. subjects in both groups must had experience at least 6 months before admitting demand...