The vertebral heart size (VHS) is used to objectively assess cardiac dimensions on thoracic radiographs. A high VHS suggest the presence of pathology, such as dilated cardiomyopathy, degenerative atrioventricular valvular disease, pericardial effusion, pericardioperitoneal diaphragmatic hernia, tricuspid dysplasia, ventricular septal defect, or patent ductus arteriosus, among others. However, breed body conformation can influence VHS. Because Greyhounds have a prevalence physiologic systolic...

Abstract Objective —To evaluate serum cardiac troponin I (cTnI) concentrations in Boxers with arrhythmogenic right ventricular cardiomyopathy (ARVC), unaffected (control) Boxers, and control non-Boxers. Animals —10 a clinical diagnosis of ARVC defined by ≥ 1,000 premature complexes (VPCs)/24 h on an ambulatory ECG, 10 assessed as normal the presence < 5 VPCs/24h, Procedures —Serum was extracted from blood sample each dog. Analysis cTnI performed. Results —Mean ± SD concentration 0.142...

Background Boxer arrhythmogenic right ventricular cardiomyopathy ( ARVC ) is a disease that may result in sudden death or heart failure. Hypothesis/objectives To prospectively study the natural history of . Animals 72 dogs (49 , 23 controls). Methods Boxers >1 year age were recruited for annual reevaluation. Controls defined as being ≥6 years and having <50 premature complex VPC s)/24 h. was ≥300 s/24 h absence other disease. Dogs genotyped striatin deletion when possible. Descriptive...

Background: The Doberman Pinscher is one of the most common breeds dogs to develop dilated cardiomyopathy (DCM), a primary heart muscle disorder characterized by myocardial dysfunction, cardiac arrhythmias, and congestive failure. In Pinscher, disease typically adult onset, familial etiology has been suggested. Hypothesis: DCM in linked specific genetic marker. Animals: study comprised an extended family Pinschers with history DCM. Methods: Participating were prospectively evaluated over...

Background : The Doberman Pinscher is one of the most common breeds dogs to develop dilated cardiomyopathy (DCM), a primary heart muscle disorder characterized by myocardial dysfunction, cardiac arrhythmias, and congestive failure. In Pinscher, disease typically adult onset, familial etiology has been suggested. Hypothesis DCM in linked specific genetic marker. Animals study comprised an extended family Pinschers with history DCM. Methods Participating were prospectively evaluated over...

To identify clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy echocardiographic evidence of left ventricular systolic dysfunction.Retrospective study.48 mature Boxers.Medical records were reviewed for information on age; sex; physical examination findings; results electrocardiography, 24-hour ambulatory thoracic radiography, echocardiography.Mean age the dogs was 6 years (range, 1 to 11 years). Twenty (42%) had a murmur, 9 (19%) ascites....

Background: Cardiac troponin I (cTnI) is a polypeptide found specifically in cardiac muscle tissue that has been used as diagnostic and prognostic indicator of cardiomyopathy. Increases cTnI are associated with myocardial pathologic processes. However, high serum concentrations have observed normal Greyhounds. Hypothesis: We hypothesized Greyhounds higher than non‐Greyhound dogs, separate reference range should be established for Animals: Blood samples were collected from the jugular vein...

Right ventricular (RV) dysfunction is a cause of exercise intolerance, hypotension, syncope, and heart failure in dogs with cardiac respiratory disorders. The study objective was to determine Doppler-derived reference values that reflect global RV function healthy dogs. We measured systolic time intervals an index myocardial performance (IMP) 45 between 8 months years age. Pulsed-wave Doppler recordings mitral, tricuspid, aortic, pulmonic were acquired. Pre-ejection period (PEP), ejection...

To determine the prevalence of ventricular arrhythmias in clinically normal adult Boxers.Prospective cross-sectional study.301 Boxers (181 females and 120 males) > 1 year old with echocardiographically systolic function no history syncope or congestive heart failure.Physical examination, which included echocardiography, was performed on all dogs. A 24-hour ambulatory ECG each dog, results were evaluated to assess arrhythmias. Statistical evaluation correlations between total number premature...

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a myocardial disease characterized by fibrofatty replacement of the ventricle and tachyarrhythmias, reported most commonly in Boxer dog. Although ARVC as disease, impact on function has not been well studied.To noninvasively evaluate anatomy dogs with ARVC.Five adult 5 healthy size-matched hound dogs.Magnetic resonance imaging was performed an ECG-gated conventional 1.5-T scanner using dark blood cine acquisitions. Images were...

Abstract Current clinical assessment of functional tricuspid valve regurgitation relies on metrics quantified from medical imaging modalities. Although these methodologies are generally successful, the lack detailed information about mechanical environment presents inherent challenges for assessing regurgitation. In present study, we have developed a finite element‐based in silico model one porcine (TV) geometry to investigate how various pathological conditions affect overall biomechanical...

Abstract Objective —To determine whether Boxers with a clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased plasma concentrations brain natriuretic peptide (BNP), compared in clinically normal dogs. Animals —13 ARVC, 9 Boxers, 10 non-Boxer dogs, and 5 hound dogs systolic dysfunction. Procedure —All were evaluated via 24-hour ambulatory electrocardiography echocardiography; the number premature contractions (VPCs) per 24 hours was assessed. Hound cardiac...

Right ventricular (RV) dysfunction is a cause of exercise intolerance, hypotension, syncope, and heart failure in dogs with cardiac respiratory disorders. The study objective was to determine Doppler-derived reference values that reflect global RV function healthy dogs. We measured systolic time intervals an index myocardial performance (IMP) 45 between 8 months years age. Pulsed-wave Doppler recordings mitral, tricuspid, aortic, pulmonic were acquired. Pre-ejection period (PEP), ejection...

The tricuspid valve (TV) is composed of three leaflets that coapt during systole to prevent deoxygenated blood from re-entering the right atrium. connection between TV leaflets’ microstructure and tissue-level mechanical responses has yet be fully understood in biomechanics society. This pilot study sought examine load-dependent collagen fiber architecture leaflets, by employing a multiscale, combined experimental approach utilizes biaxial characterizations, micro-level quantification,...

Nineteen of 28 (67%) Greyhounds enrolled in the Blood Donor Program at The Veterinary Teaching Hospital, Ohio State University (Columbus, OH), had a left basilar systolic murmur. Ten with murmurs and 9 without were evaluated to gain knowledge about pathogenesis this Echocardiograms performed sedation by means GE Vivid 7 Echocardiographic System continuous ECG; arterial blood pressure (SABP) was measured an Ultrasonic Doppler Flow detector model 811‐B. mean peak aortic velocity (2.15 m/s;...

Background : Double‐chambered right ventricle (DCRV) is a frequently recognized cardiac congenital abnormality in humans. It has been described dogs and 1 cat. However systemic description of clinical echocardiographic features the disease cats currently lacking from veterinary literature. Animals Nine with DCRV are described. Results The ranged 4 months to 10 years age. Eight at presentation were asymptomatic cat had chylothorax. In all cases echocardiography revealed abnormal fibromuscular...

This dataset contains the anisotropic tissue responses of porcine atrioventricular valve leaflets to force-controlled biaxial mechanical testing. The set includes first Piola-Kirchhoff Stress and specimen stretches (λ) in both circumferential radial directions (C R, respectively) for mitral anterior posterior (MVAL MVPL), tricuspid anterior, posterior, septal (TVAL, TVPL, TVSL) from six hearts at five separate loading protocols. is associated with a companion journal article, which can be...

Fitness assessment of horses remains challenging. Heart rate variability (HRV) can be used to monitor human athlete's training, but its value is unknown in horses.

Background: Double-chambered right ventricle (DCRV) is a frequently recognized cardiac congenital abnormality in humans.It has been described dogs and 1 cat.However systemic description of clinical echocardiographic features the disease cats currently lacking from veterinary literature.Animals: Nine with DCRV are described.Results: The ranged 4 months to 10 years age.Eight at presentation were asymptomatic cat had chylothorax.In all cases echocardiography revealed abnormal fibromuscular...

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is prevalent in the Boxer. There little information on temporal variability of arrhythmias within affected dogs.To evaluate ambulatory electrocardiograms (AECG) from Boxers with ARVC for hourly variation premature complexes (PVC) and heart rate (HR).One hundred sixty-two Boxer dogs ARVC.Retrospective, observational study 1,181 AECGs collected at The Ohio State University 1997 to 2004 was evaluated. proportion depolarizations that were...