PRéCIS:: The present study demonstrates that surgical success rate of gonioscopy-assisted transluminal trabeculotomy (GATT) is 83.7% according to target intraocular pressure (IOP) ≤21 mm Hg and ≥20% reduction from baseline in patients with moderate advanced glaucoma, an average follow-up 19.4 months.The aim the was assess outcomes GATT eyes open-angle glaucoma.A retrospective included 104 patients, a mean age 58.9±18.5 (15 87) years, who underwent using 6/0 prolene suture treat glaucoma....

Gonioscopy-assisted transluminal trabeculotomy (GATT) provided effective intraocular pressure (IOP) control in primary congenital glaucoma (PCG). Also, approximately two third of patients did not need antiglaucoma medication at an average follow-up 1 year after surgery.The purpose this study was to assess the safety and efficacy GATT surgery eyes with PCG.This is a retrospective review who underwent for PCG. Outcome measures were changes IOP number medications all time points (1, 3, 6, 9,...

A bstract Background: To investigate the neuroprotective effects of topically applied brimonidine tartrate 0.2% (BMD), an α 2 ‐receptor agonist, on retinal ganglion cell (RGC) layer and inner nuclear (INL) rabbit retina in endothelin‐1 (ET‐1)‐induced optic nerve (ON) ischaemia model. Methods: Osmotic minipumps were surgically implanted into one eye 16 New Zealand Albino rabbits to deliver ET‐1 at constant rate 0.5 μL/h for weeks. Eyes divided four groups. was given with (Group 3) without...

We report a case of bilateral Descemet membrane detachment (DMD) after canaloplasty in 70-year-old Portuguese man with primary open-angle glaucoma. The patient developed DMD immediately following consecutive (1 week apart) surgery both eyes. Slitlamp biomicroscopy, gonioscopy, and Fourier-domain optical coherence tomography (FD-OCT) findings are described. On postoperative day 1, cases, slitlamp biomicroscopy revealed an unscrolled inferonasal clear cornea deep quiet anterior chambers....

We aimed to create mechanic optic nerve injury model in rats and investigate the neuroprotective effects of topical Coenzyme Q10 + Vitamin E (CoQ Vit.E) molecules on retinal ganglion cells.Mechanic was created right eyes (n = 12). Rats were divided into two groups: glaucoma with sham treatment CoQ Vit.E treatment. Treatment applied for 4 weeks. Glial fibrillary acidic protein, Brn-3a antibody, anti-Iba1 examined by immunohistochemistry. Bax, Bcl-xL, Tfam protein expression measured Western...

A bstract Background: To compare the effects of variable mitomycin‐C (MMC) applications during trabeculectomy on target intraocular pressure (IOP), number antiglaucomatous therapy, bleb morphology and surgical complications. Methods: 66 glaucoma cases who underwent combined with small‐area (Group 1) or large‐area 2) MMC application were included. This study is a retrospective case series comparison. In Group 1, had only been applied to scleral flap area, whereas additional performed upper...

AIm:To investigate the effects of neurogenically-induced autologous bone marrow-derived mesenchymal stem cells (NIBM-MSCs) in paraplegic dogs without deep pain perception (DPP) secondary to intervertebral disk disease (IVDD).mATeRIAL and meTHods: Seven which could not be improved neurologically with conventional treatment modalities were included study.All diagnosed by magnetic resonance imaging surgically treated.Each dog received two times a suspension 5.0x10 6 NIBM-MSCs, positive CNPase...

To report a case of primary congenital glaucoma associated with paracentral acute middle maculopathy.A report.A 14-year-old girl undiagnosed was referred for the evaluation sudden vision loss week after initial symptoms. Visual acuity counting fingers at 2 m in right eye. Examination her eye revealed corneal stromal scar like Haab striae, splinter hemorrhage temporal border optic disk, perivenular hemorrhage, and fern-like white area macula. On optical coherence tomography eye,...

Précis: The present study demonstrates that surgical success rates of gonioscopy-assisted transluminal trabeculotomy (GATT) with a target intraocular pressure (IOP)≤21 mm Hg are 93.3% (for qualified success) and 26.7% complete in vitrectomized patients exhibiting secondary open-angle glaucoma (SOAG) after silicone oil (SO) removal, for an average follow-up 37.5 months. Purpose: To report the long-term outcomes GATT SOAG SO removal. Setting: Retrospective case-series study. Patient...

The purpose of this study was to report 2 cases experiencing a transient decrease in their vision due the development acute myopia after an uneventful prolene gonioscopy-assisted transluminal trabeculotomy (GATT) surgery.A 52-year-old woman with primary open-angle glaucoma and 8-year-old boy juvenile underwent GATT surgery.On postoperative first day, both patients had mild shallow anterior chamber intraocular pressures measured as 19 16 mm Hg, respectively. Both -4.5 -6.0 D, Fundus...

Précis: The present study demonstrates that the surgical success rate of circumferential trabeculotomy is 64.7% according to target intraocular pressure (IOP) ≤21 mm Hg and ≥30% reduction from baseline in patients with neonatal-onset primary congenital glaucoma (PCG), an average follow-up 35.1 months. Purpose: aim was evaluate applicability compared converted traditional PCG Turkey. Patients Methods: A retrospective enrolled 42 eyes age 34.0±6.7 (14 59) days at time surgery, who underwent...

To determine if proteasome inhibition using MG132 increased the efficiency of FIV vector-mediated transduction in human trabecular meshwork (TM)-1 cells and monkey organ-cultured anterior segments (MOCAS).TM-1 were pretreated for 1 hour with 0.5% dimethyl sulfoxide (DMSO; vehicle control) or 5 to 50 μM transduced FIV.GFP (green fluorescent protein)- FIV.mCherry-expressing vector at a multiplicity (MOT) 20. At 24 hours, fixed stained antibodies GFP, positive counted, manually by...

Purpose To investigate whether the central corneal thickness (CCT) shows alterations in Graves disease and ophthalmopathy (GO) cases according to severity hormonal status of patients. Methods A total 150 patients (62 male, 88 female) with 32 control subjects (11 21 were included study. The divided into six groups orbital involvement thyroid hormone status. Best-corrected visual acuity, pupillary responses, color vision, biomicroscopy, CCT, intraocular pressure, funduscopy performed,...

To evaluate the effect of erythropoietin (EPO) treatment on retinal nerve fiber layer (RNFL) parameters in patients with chronic renal failure (CRF) undergoing peritoneal dialysis (PD).Fifty-eight eyes 29 CRF PD were evaluated. Fifteen have been treated EPO (group 1), 14 without 2), and 30 15 age-matched normal control subjects assessed group 3. A complete ophthalmologic examination RNFL measurements performed for each patient after PD. Anemia also measured. thickness protocol was used to...