Aim: The current data have proven the pivotal role of inflammation in development atherosclerosis and cardiovascular diseases patients with chronic kidney disease (CKD). Neutrophil to lymphocyte (N/L) ratio has increasingly been reported as a measure systemic inflammation. This study assessed N/L investigated its associations standard inflammatory biomarkers different stages CKD patients. Material methods: cross-sectional included 30 predialysis, 40 hemodialysis, 35 peritoneal dialysis...

Atherosclerosis is a disease of the arterial wall, with increasing wall thickness representing an early event in progression disease. It has been suggested that iron overload, as assessed by increased serum ferritin concentration, may be risk factor for atherosclerosis. The aim this study was to investigate relationship between influence intravenous (IV) therapy and levels carotid intima media (C-IMT) dialysis patients. Sixty patients (51 ± 14) years were divided into two groups according...

Objective: Hemodialysis patients may be at risk for malnutrition due to catabolic effects caused by dialysis, loss of amino acids, inadequate nutrient intake, acidosis, and inflammation. Malnutrition have negative on quality life, mortality, disease prognosis. This study was conducted determine the relationship between anthropometric parameters, depression, life with Inflammation Score (MIS) 55 aged 18 65 years (36 males 19 females) who dialysis treatment 3 days per week least months...

Granulomatosis with polyangiitis (GPA) is a rare necrotizing vasculitis, which usually involves the upper and lower respiratory systems kidneys often have relapsing course. Neutrophil/lymphocyte ratio (NLR) has been shown to be useful marker predicting not only progressive disease, but also mortality in various inflammatory diseases. We aimed investigate roles of NLR extend clinical involvement prognosis patients GPA.Consecutive newly diagnosed GPA who had follow-up for at least 6 months...

Sleep complaints are common in end-stage renal disease. We aimed to investigate the relationship between sleep-related and inflammatory cytokines haemodialysis (HD) patients, also effects of HD on sleep patterns cytokine levels.Predialysis serum interleukin-1beta (IL-1beta), interleukin-6 (IL-6) tumour necrosis factor-alpha (TNF-alpha) levels nine patients with were compared those without healthy controls. Patients underwent polysomnography night after following night.Patients had...

This study was performed to investigate the potential relationship between left ventricular hypertrophy (LVH) and proinflammatory cytokines in hemodialysis (HD) patients effect of HD on cytokine production. Serum interleukin 1 beta (IL-1 β), 6 (IL-6) tumor necrosis factor alpha (TNF-α) measurements echocardiographic studies were 35 stable patients. A variety probable risk factors for LVH including age, duration, blood pressure (BP), body mass index, lipid profile, hemoglobin, albumin,...

The existence of microalbuminuria (MAU) in patients with essential hypertension is a strong indicator microvascular damage. Although endothelial dysfunction and increased vascular permeability both have role the development MAU, its ethiopathogenesis hypertensive not yet clearly understood. Vascular growth factor (VEGF) most important regulator pathological or physiological angiogenesis it additionally leads to permeability. This study aims assess relationship serum VEGF levels MAU...

Abstract Hypertension, non‐dipper blood pressure ( BP ) pattern and decrease in daily urine output have been associated with left ventricular hypertrophy LVH peritoneal dialysis PD patients. However, there is lack of data regarding the impact different regimens on these factors. We aimed to investigate circadian rhythm end‐stage renal disease patients using automated APD or continuous ambulatory CAPD modalities. Twenty (7 men, 13 women) 28 (16 12 were included into study. 24‐h monitoring...

Abstract YKL‐40 has been introduced as a marker of inflammation in different clinical situations. The association between and chronic renal failure patients not researched currently. objectives this study were to establish serum concentrations dialysis with compared healthy subjects explore its relationships proinflammatory cytokine, interleukine‐6 (IL‐6) an acute phase mediator, high sensitivity C‐reactive protein (hs‐CRP). population included hemodialysis ( N = 43; mean age 40.9 ± 14.5),...

Background: Diabetic nephropathy (DN) is a leading cause of diabetes-related morbidity and mortality. The aim this study was to evaluate the relationship AGT M235T apoprotein E (APO E) gene polymorphism with DN in Turkish patients Type 2 diabetes, compare genotype allele distributions among patients, non-DN healthy controls. Methods: APO analysis were performed 111 108 106 control subjects for genotype, 100 polymorphism. determined by RFLP-PCR. Results: frequencies ε2/3, ε 3/3, 3/4 genotypes...

Background. To evaluate the effects of everolimus on renal ischemia-reperfusion injury (IRI). Methods. Wistar albino rats were divided into control, (IR), and ischemia-reperfusion/everolimus (IR/eve) groups. Everolimus was administered for seven consecutive days to IR/eve group prior injury. IR groups underwent forty-five minutes ischemia followed by application reperfusion at 2 24 hours. Blood samples kidneys taken from all animals. Results. Serum blood urea nitrogen creatinine levels...

Uremia is associated with accelerated atherosclerosis and increased cardiovascular mortality in patients end-stage renal disease (ESRD). Cardiac injury markers, such as myoglobin, creatine kinase-MB (CK-MB), or troponins, frequently used to recognize acute coronary events, may be falsely elevated this patient group. In study, our aim was (i) test serum levels of CK-MB, troponin I (cTnI) ESRD without artery (CAD) compare the results healthy controls (ii) investigate association between these...

To determine the significance of a newly described marker inflammation procalcitonin (PCT), and to investigate its relationship conventional markers inflammation, such as C-reactive protein (CRP), fibrinogen, erythrocyte sedimentation rate (ESR), in patients on peritoneal dialysis (PD) with peritonitis.A prospective, observational clinical study.The Nephrology Division University-affiliated teaching hospital.51 consecutive PD were included study. Of this number, 16 developed peritonitis...

The incidence of nephrotic syndrome co-existing with chronic lymphocytic leukemia (CLL) is a rare condition. Almost any glomerular pathology may accompany CLL. most frequent all membranoproliferative glomerulonephritis (MPGN). Moreover, in 5 - 10% patients CLL, monoclonal gammopathy be detected serum and/or urine samples. There are no well-established treatment protocols for those CLL accompanying syndrome. In this case report, we present 55-year-old female patient diagnosed developing...

We present a 62-year-old man, with prior history of diabetes mellitus, atherosclerotic heart disease, and chronic renal failure requiring peritoneal dialysis, who developed accelerated uremic sensorimotor polyneuropathy. Our patient significantly improved after effective hemodialysis. Although transplantation is curable therapy for neuropathy, dialysis still an important treatment the group patients cannot undergo transplantation.

The purpose of this study was to determine the prevalence oral Candida spp. in HD patients and investigate its relation with systemic inflammation atherosclerosis. Microbiological samples were taken from buccal mucosa, palate, dental prosthesis a cotton swab. High-sensitivity CRP (hsCRP) IL-6 measured as markers. A total 69 (58% male median age 62 years) enrolled study; 53.6% had colonization. HsCRP levels found be significantly higher colonization positive group than negative (P = 0.002 P...

Visfatin was recently defined as an adipocytokine; however, the pathophysiological role of visfatin is not completely understood. A few studies suggest that may be a new proinflammatory adipocytokine. The aim present study to compare serum levels between hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) patients evaluate relationship IL-6, TNF-α, left ventricular hypertrophy. Serum visfatin, TNF-α were measured by using ELISA method, echocardiographic evaluations performed in...