A5000856613- Opioid Use Disorder Treatment
- Pain Management and Opioid Use
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Musculoskeletal pain and rehabilitation
- Substance Abuse Treatment and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Medication Adherence and Compliance
- Prenatal Substance Exposure Effects
- Schizophrenia research and treatment
- Lung Cancer Treatments and Mutations
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmaceutical studies and practices
- Bipolar Disorder and Treatment
- Asthma and respiratory diseases
- Lung Cancer Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Blood Pressure and Hypertension Studies
- Lung Cancer Research Studies
- Healthcare Policy and Management
- Child and Adolescent Psychosocial and Emotional Development
- Cardiac Arrest and Resuscitation
- Inflammatory mediators and NSAID effects
- Mobile Health and mHealth Applications
University of Arkansas for Medical Sciences
2016-2025
Martin University
2025
Asuragen (United States)
2023
Medicines Evaluation Unit
2012-2022
United States Air Force Academy
2022
Michigan Medicine
2021
Center for Drug Evaluation and Research
2021
University of Florida
2021
University of Arizona
2021
University Hospitals of Cleveland
2019
Because long-term opioid use often begins with treatment of acute pain (1), in March 2016, the CDC Guideline for Prescribing Opioids Chronic Pain included recommendations duration therapy and type to select when is initiated (2). However, data quantifying transition from chronic are lacking. Patient records IMS Lifelink+ database were analyzed characterize first episode among commercially insured, opioid-naïve, cancer-free adults quantify increase probability opioids each additional day...
Objective: To identify the adherence value cut-off point that optimally stratifies good versus poor compliers using administratively derived measures, medication possession ratio (MPR) and proportion of days covered (PDC) hospitalization episode as primary outcome among Medicaid eligible persons diagnosed with schizophrenia, diabetes, hypertension, congestive heart failure (CHF), or hyperlipidemia.Research design methods: This was a retrospective analysis Arkansas administrative claims data....
Increasing rates of opioid use disorders (OUDs) (abuse and dependence) among patients prescribed opioids are a significant public health concern. We investigated the association between exposure to prescription incident OUDs individuals with new episode chronic noncancer pain (CNCP) condition.
Opioids are widely prescribed for non-cancer pain conditions (NCPC), but there have been no large observational studies in actual clinical practice assessing patterns of opioid use over extended periods time. The TROUP (Trends and Risks Opioid Use Pain) study reports on trends therapy NCPC two disparate populations, one national commercially insured population (HealthCore plan data) state-based publicly-insured (Arkansas Medicaid) a six year period (2000-2005). We track enrollees with the...
The use of chronic opioid therapy (COT) for non-cancer pain (CNCP) has increased dramatically in the past two decades. There also been a marked increase abuse prescribed opioids and accidental overdose. Misuse may link these trends, but thus far only studied small clinical samples. We therefore sought to validate an administrative indicator misuse among large samples recipients COT determine demographic, clinical, pharmacological risks associated with possible probable misuse. A total 21,685...
Objectives Use of prescription opioids for chronic pain is increasing, as abuse these medications, though the nature link between trends unclear. These increases may be most marked in patients with mental health (MH) and substance use disorders (SUDs). We analyzed 2000 2005 opioid prescribing among individuals noncancer conditions (NCPC), without MH SUDs. Methods Secondary data analysis longitudinal administrative from 2 dissimilar populations: a national, commercially insured population...
Objective.–To assess the scaling properties, reliability, and validity of revised Migraine‐Specific Quality Life Questionnaire (MSQ) (Version 2.1) Background.–The MSQ is a disease‐specific, quality‐of‐life instrument with three hypothesized scales that has been developed, tested, revised. Methods.–The study used multicenter, nondrug, prospective, parallel group, quasi‐experimental design. Patients migraine were recruited at outpatient headache specialty practices administered MSQ, Medical...
<h3>Background</h3> There has been an increase in overdose deaths and emergency department visits (EDVs) involving use of prescription opioids, but the association between opioid prescribing adverse outcomes is unclear. <h3>Methods</h3> Data were obtained from administrative claim records Arkansas Medicaid HealthCore commercially insured enrollees, 18 years older, who used opioids for at least 90 continuous days within a 6-month period 2000 2005 had no cancer diagnoses. Regression analysis...
Article AbstractObjective: To determine the prevalence, trends, and factors associated with antipsychotic polypharmacy categorized according to type of duration use contrast usage patterns published treatment guidelines. Method: A retrospective cohort study was designed, Medicaid recipients >= 16 years age a schizophrenia diagnosis (ICD-9-CM =295.xx) between 1998 2000 were identified from California (20% random sample) Georgia claims databases. Use based on (long-term defined as lasting > 2...
BACKGROUND Multiple measures of adherence have been reported in the research literature and it is difficult to determine which best, as each nuanced. Occurrences medication switching polypharmacy or therapeutic duplication can substantially complicate calculations when a class sought. OBJECTIVE To contrast Proportion Days Covered (PDC) metric with 2 variants Medication Possession Ratio (MPR, truncated MPR). METHODS This study was retrospective analysis North Carolina Medicaid administrative...
To compare the predictive validity of 8 different adherence measures by studying variability explained between each measure and 2 outcome measures: hospitalization episodes total nonpharmacy cost among Medicaid eligible persons diagnosed with diabetes.This study was a retrospective analysis Arkansas administrative claims data from January 2000 to December 2006.Diabetic (ICD-9-CM = 250.0 x - 250.9 x, where 0 or 2) patients were identified in recruitment period July through April 2004....
Abstract Benzodiazepines and opioids are commonly used among veterans suffering from mental health disorders pain conditions. The objective of this study is to determine whether concomitant benzodiazepine-opioid use increases the incidence adverse outcomes above baseline risk nonacute opioid-only use. dataset contained all who filled at least 1 opioid prescription during years 2008 2012. Nonacute was defined as having prescriptions greater than or equal 20 days within a 60-day period....
Among Veterans Health Administration patients with chronic noncancer pain, opioid therapy occurs frequently, but the median daily dose is usually modest. Although opioids are frequently prescribed for pain (CNCP) among (VHA) patients, little has been reported on national prescribing patterns in VHA. Our objective was to better characterize dosing and duration of CNCP We analyzed VHA administrative pharmacy data fiscal years 2009 2011. For individuals diagnoses any use year, we calculated...