A5084061667- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Spine and Intervertebral Disc Pathology
- Bone fractures and treatments
- RNA modifications and cancer
- Cervical and Thoracic Myelopathy
- Management of metastatic bone disease
- Bone Tissue Engineering Materials
- Block Copolymer Self-Assembly
- Advanced Polymer Synthesis and Characterization
- Advancements in Transdermal Drug Delivery
- MicroRNA in disease regulation
- Advanced Drug Delivery Systems
- Immune Cell Function and Interaction
- Pediatric Pain Management Techniques
- Extracellular vesicles in disease
- Shoulder Injury and Treatment
- Hip disorders and treatments
- Pickering emulsions and particle stabilization
- Nanoparticles: synthesis and applications
- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Protein Interaction Studies and Fluorescence Analysis
China University of Geosciences (Beijing)
2025
Second Affiliated Hospital of Jilin University
2017-2024
Zhejiang Sci-Tech University
2021-2022
Nanjing University of Chinese Medicine
2021
Second Military Medical University
2013-2014
To engineer bone tissue, an ideal biodegradable implant should be biocompatible, biodegradable, osteoinductive and osteoconductive.
Living crystallization-driven self-assembly (CDSA) is a powerful approach to tailor nanoparticles with controlled size and spatially defined compositions from amphiphilic crystalline block copolymers (BCPs). However, variety of external constraints usually make the successful applications living CDSA difficult. Herein, such arising strong hydrogen-bond (H-bond) interactions between unimers that lead failure are effectively overcome via reduction H-bond strength. In particular, by adding...
Recent evidence has demonstrated that mesenchymal stem cells (MSCs) can release a large number of functionally specific microRNA (miRNA) microvesicles play role in promoting osteogenic differentiation, but the mechanism is not yet clear. Under such context, this study aims to elucidate bone marrow cell-derived exosomes (BMSC-Exo) fracture healing mice. We isolated and identified BMSC-Exo. Bioinformatics analysis predicted high expression miRNA verified transfer miR-25 by immunofluorescence....
The fabrication of hybrid hierarchical assemblies involving inorganic and organic building blocks has received a significant amount attention as result their facile tunability potential applications. However, precise design architectures still remains challenge because the difficulty control over incompatibility blocks. Crystallization-driven self-assembly (CDSA) block copolymers is powerful method in preparation complex semicrystallized structures from nano- to microscale, with controlled...
Purpose: Insufficient biological activity heavily restricts the application and development of biodegradable bone implants. Functional modification implants is critical to improve osseointegration regeneration. Methods: In this study, L-lysine functionalized graphene oxide (Lys-g-GO) nanoparticles polydopamine-assisted gold nanoparticle (AuNPs-PDA) coatings were applied function PLGA scaffold materials. The effects Lys-g-GO AuNPs-PDA on physicochemical properties scaffolds detected with...
HCC is a major contributor to cancer-related mortality worldwide. Curative treatments are available for minority of patients diagnosed at early stages; however, only few multikinase inhibitors and marginally effective in advanced cases, highlighting the need novel therapeutic targets. One potential target protein arginine methyltransferase, which catalyzes various forms methylation often overexpressed cancers. However, diverse expression patterns clinical values PRMTs remain unclear. In...
Summary Introduction Primary filum terminale ependymoma ( PFTE ) is a unique type of ependymomas and locates on extramedullary site. However, the clinical features prognostic factors are still unknown due to its rarity. Aim This study aimed evaluate features, outcomes, in largest series cases. Result Thirty‐eight patients were included this study. Gross total removal GTR tumors was achieved 33(87%) patients. Five (13%) had subtotal resection STR ). For residual tumors, postoperative...
Abstract Rationale: The aim of the present study was to assess efficacy and safety percutaneous cannulated screw (PCS) implantation assisted by view model navigation (SVMN) treat femoral neck fracture (FNF). Patient concerns: A 42-year-old male patient suffered from a high falling injury, causing pain, swelling, deformity, limited mobility on his right hip. Diagnoses: He diagnosed with Garden type I FNF. Interventions: PCS SVMN used in this patient. Outcomes: follow up lasted for 48 months....
Shibo Wei, Yan Zhang, Baeki E. Kang, Wonyoung Park, He Guo, Seungyoon Nam, Jong-Sun Jee-Heon Jeong, Yunju Jo, Dongryeol Ryu, Yikun Jiang & Ki-Tae Ha. BMB Reports -0001;0:. https://doi.org/10.5483/BMBRep.2023-0214
The coronoid process of the ulna, as a key part elbow joint, plays an important role in maintaining joint stability. Reconstruction is necessary both acute and chronic defects to restore stability avoid early degeneration. olecranon tip may be useful autologous osteochondral graft for reconstructing same shape ulna process. purpose this report was verify if reconstruction with can kinematics. Here, we 13-year-old boy who had undergone Kirschner-wire fixation left supracondylar fracture...
Abstract Rationale: In this paper, the efficacy and safety of using navigated drilling arthroscopy (NDA) to assist surgery for ulnar–radial joint dislocation caused by epiphyseal premature closure (EPC) are described. Deformity correction was mentioned in literature, but there were numerous complications, example, poor correction, infection, neurovascular injury, osteofascial compartment syndrome, failure internal fixation, nonunion after osteotomy. order minimize surgical we utilized finish...
Abstract Background Forearm crisscross injury is rare in children; there no relevant literature so far. Surgeons lack experience and knowledge treating this type of injury. We report a case forearm child for the first time analyze its mechanism, use minimally invasive treatment to obtain good therapeutic effects. Case presentation An 8-year-old boy experienced pain his left when he accidentally fell while skateboarding. Physical examination revealed swelling deformity forearm. performed...
Background Forearm crisscross injury is rare in children; there no relevant literature so far. Surgeons lack experience and knowledge treating this type of injury. We report a case forearm child for the first time analyze its mechanism. Case summary An 8-year-old boy experienced pain his left when he accidentally fell while skateboarding. Physical examination revealed swelling deformity forearm. performed imaging results radial head dislocation, distal epiphyseal separation from shaft,...