A5052743673- Cancer Cells and Metastasis
- Glycosylation and Glycoproteins Research
- Adipokines, Inflammation, and Metabolic Diseases
- Protein Tyrosine Phosphatases
- Calcium signaling and nucleotide metabolism
- Growth Hormone and Insulin-like Growth Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Antioxidant Activity and Oxidative Stress
- Liver Disease Diagnosis and Treatment
- Connexins and lens biology
- Neurogenetic and Muscular Disorders Research
- Bone and Joint Diseases
- Adipose Tissue and Metabolism
- Acute Myeloid Leukemia Research
- Ion Channels and Receptors
- Galectins and Cancer Biology
- Tea Polyphenols and Effects
- Calpain Protease Function and Regulation
- Hematological disorders and diagnostics
- Atherosclerosis and Cardiovascular Diseases
- Parkinson's Disease Mechanisms and Treatments
- Diet, Metabolism, and Disease
- Amyotrophic Lateral Sclerosis Research
- Metabolism, Diabetes, and Cancer
Mokpo National University
2015-2023
Baylor College of Medicine
2008-2023
Ewha Womans University
2016
Korea Research Institute of Bioscience and Biotechnology
2010
Seoul National University
2005
Objective Decreased adiponectin and increased leptin plasma concentrations are believed to be associated with the occurrence progression of cancers such as endometrial cancer breast cancer. The aim this study was explore association levels development ovarian Methods For patients control group, were measured; anthropometric data obtained during a chart review. Statistical comparisons between groups analyzed using Student's t-test; correlations confirmed Pearson correlation. Results mean in...
Abstract Purpose: This study aimed to test the ability of a new insulin-like growth factor receptor (IGF-IR) tyrosine kinase inhibitor, BMS-536924, reverse constitutively active IGF-IR (CD8-IGF-IR) transform MCF10A cells, and examine effect inhibitor on range human breast cancer cell lines. Experimental Design: CD8-IGF-IR-MCF10A cells were grown in monolayer culture, three-dimensional (3D) as xenografts, treated with BMS-536924. Proliferation, cycle, polarity, apoptosis measured....
Camellia japonica is a popular garden plant in Asia and widely used as cosmetic sources traditional medicine. However, the possibility that C. affects cardiovascular system remains unclear. The aim of present study was to evaluate vascular effects an extract japonica. Vascular reactivity assessed organ baths using porcine coronary arteries inhibition proliferation migration were human smooth muscle cells (VSMCs). All four different parts, leaf, stem, flower, fruits, caused...
BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis mature as well suppressing differentiation preadipocytes plays an important role in preventing obesity.This study examines anti-adipogenic and pro-apoptotic effect red pepper seed water extract (RPS) prepared at 4°C (RPS4) 3T3-L1 cells.MATERIALS/METHODS: Effect RPS4 or its fractions on lipid accumulation was determined cells using oil O (ORO) staining.The expressions AMP-activated protein kinase (AMPK) adipogenic...
This study was designed to investigate the effect of soybean leaf extract on development hepatic steatosis in high fat diet-fed mice. Soybean plants were treated with ethephon enhance production isoflavones leaves. The mice fed normal chow diet(ND), diet(HFD) or HFD+Soybean for 9 weeks. HFD feeding significantly increased body weight gain and visceral subcutaneous adipose tissue weights compared ND group mice, but these increases attenuated by treatment. also lipid droplet hepatocellular...
TMEM16A is a Ca²⁺-activated Cl⁻ channel found in secretory glands, GI and respiratory tracts, sensory organs, playing major physiological role fluid secretion, autonomous motility, transduction. In addition, overexpression of has been associated with cancer cell proliferation invasion. Suppression upregulated proposed as an effective anti-cancer strategy. While searching for potential inhibitor, components rice bran attracted our attention due to their colon cells, type cells known...
As a study on the satisfaction of self-nail treatment services at specialty stores, experimental method was surveyed by total 145 women in their teens and 40s living Seoul area, 25 people who agreed to survey were selected after explaining purpose, contents research procedures experiment. The results are as follows: Self-nail is periodic for 2 1 month, reason preference highest mood swings. Considering that holding power or 3 weeks, most appropriate period considered be weeks. When receiving...
<div>Abstract<p><b>Purpose:</b> This study aimed to test the ability of a new insulin-like growth factor receptor (<i>IGF-IR</i>) tyrosine kinase inhibitor, BMS-536924, reverse constitutively active <i>IGF-IR</i> (<i>CD8-IGF-IR</i>) transform MCF10A cells, and examine effect inhibitor on range human breast cancer cell lines.</p><p><b>Experimental Design:</b><i>CD8-IGF-IR</i>-MCF10A cells were...
<div>Abstract<p><b>Purpose:</b> This study aimed to test the ability of a new insulin-like growth factor receptor (<i>IGF-IR</i>) tyrosine kinase inhibitor, BMS-536924, reverse constitutively active <i>IGF-IR</i> (<i>CD8-IGF-IR</i>) transform MCF10A cells, and examine effect inhibitor on range human breast cancer cell lines.</p><p><b>Experimental Design:</b><i>CD8-IGF-IR</i>-MCF10A cells were...
Abstract Crateva unilocularis Buch-Ham has traditionally been used in Nepal for the treatment and prevention of diabetes. However, scientific verification through studies on preventive effect C. diabetes not done properly. In this study we investigated leaf extract (CULE) glucose uptake insulin resistance. The CULE an vivo system was measured using zebrafish. cell-free system, enzymes activities related to were measured. Moreover, cell-cultured RIN-m5F pancreatic beta cells, 3T3-L1...