A5021781169- Nanoplatforms for cancer theranostics
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Extracellular vesicles in disease
- Advanced biosensing and bioanalysis techniques
- Nanocluster Synthesis and Applications
- Sulfur Compounds in Biology
- Biosensors and Analytical Detection
- MXene and MAX Phase Materials
- Photoacoustic and Ultrasonic Imaging
- Spectroscopy Techniques in Biomedical and Chemical Research
- Wound Healing and Treatments
- Advanced Chemical Sensor Technologies
- Transition Metal Oxide Nanomaterials
- Gas Sensing Nanomaterials and Sensors
- Quantum Dots Synthesis And Properties
- Ovarian function and disorders
- Cancer Research and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Copper-based nanomaterials and applications
- 2D Materials and Applications
- Mitochondrial Function and Pathology
- Advanced Sensor and Energy Harvesting Materials
- Apelin-related biomedical research
- Electrochemical sensors and biosensors
Dongguan People’s Hospital
2024
Southern Medical University
2024
University of Science and Technology of China
2024
Dongguan University of Technology
2024
South China Normal University
2017-2023
Sixth Affiliated Hospital of Sun Yat-sen University
2021
Sun Yat-sen University
2021
State Administration of Traditional Chinese Medicine of the People's Republic of China
2019
Laser Research Institute
2018
State Council of the People's Republic of China
2018
A multifunctional nanoplatform based on black phosphorus quantum dots (BPQDs) was developed for cancer bioimaging and combined photothermal therapy (PTT) photodynamic (PDT). BPQDs were functionalized with PEG chains to achieve improved biocompatibility physiological stability. The as-prepared nanoparticles exhibite prominent near-infrared (NIR) red-light-triggered properties. therapeutic application of PEGylated then performed in vitro vivo. results demonstrate that the phototherapy...
The flexible wearable sweat sensor that enables real-time monitoring and noninvasive sampling is emerging as a new focal point in medical healthcare. It represents an ideal choice for analyzing the constituents human to assess individual physiological states potential related diseases. Here, we introduce plasmonic paper-based microfluidic device based on surface-enhanced Raman spectroscopy (SERS) equipped with portable spectrometer continuous situ of sweat. Extensible segmented channels...
Different from their bulk counterparts, plasmonic molybdenum oxide nanomaterials display superior optical and electronic properties, but unfortunately, phase-controlled synthesis of with multifunctional performances still remains a challenge. To actualize this, surfactant-free solvothermal strategy was proposed to fabricate tunable phase. Encouragingly, the as-prepared dioxide nanoparticles (MoO2 NPs) exhibit intense near-infrared (NIR) absorption attributed localized surface plasmon...
Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has emerged as a better candidate for deep-tissue tumor elimination. More interestingly, photothermal ablated cells also manifest somewhat immunostimulation potency to elicit antitumor immunity, although most dying are undergoing apoptosis that is commonly considered immunologically silent. Here, NIR-II responsive nanosystem established photoimmunotherapy using molybdenum dioxide (MoO2) nanodumbbells nanoconverter....
Metal-organic framework-based metal ion therapy has attracted increasing attention to promote the cascade wound-healing process. However, multimetal synergistic administration and accurately controlled release are still challenges. Herein, an aptamer-functionalized silver@cupriferous Prussian blue (ACPA) is established as a metal-based theranostic nanoagent for chronic nonhealing diabetic wound treatment. offers programmable nanoplatform formulate prescriptions, achieving cooperative...
Rapid detection of pathogens present on contaminated surfaces is crucial for food safety and public health due to the high morbidity mortality bacterial infections. Herein, a sensitive efficient method on-site identification foodborne anisotropic was developed by using an in situ instantaneously prepared surface-enhanced Raman scattering (SERS) platform. To achieve this, molybdenum-doped gallic acid-derived carbon dots (MCDs) are utilized as reductant synthesizing Au@MCDs nanohybrids within...
Oxygen deficient molybdenum oxide (MoO<sub>3−x</sub>) spurred intense scientific interest in biomedical research owing to the strong localized surface plasmon resonance (LSPR) effect NIR region.
By means of a simple and photo-induced method, four colors molybdenum oxide quantum dots (MoO<sub>x</sub> QDs) have been synthesized for surface-enhanced Raman scattering photothermal therapy.
The development of two-dimensional (2D) transition metal dichalcogenides has been in a rapid growth phase for the utilization surface-enhanced Raman scattering (SERS) analysis. Here, we report promising 2D tellurides (TMTs) material, hafnium ditelluride ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="m1"> <mml:mrow> <mml:msub> <mml:mi>HfTe</mml:mi> </mml:mrow> <mml:mn>2</mml:mn> </mml:msub> </mml:math> ), as an ultrasensitive platform identification trace...
The elevated level of hydrogen sulfide (H
Recently, two-dimensional (2D) semiconductor materials have been the focus of substantial research interest in surface-enhanced Raman scattering (SERS) because their fascinating and unique properties. Herein, 2D niobium ditelluride (NbTe2) nanosheets (NTNs) with lamellar ultrathin crystalline morphologies were easily synthesized for first time via liquid-phase exfoliation combined hydrothermal method. NTNs could serve as a low-cost metal-free SERS substrate ultrasensitive detection aromatic...
Because the breast cancer is an important factor that threatens women’s lives and health, early diagnosis helpful for disease screening a good prognosis. Exosomes are nanovesicles, secreted from cells other body fluids, which can reflect genetic phenotypic status of parental cells. Compared with methods (such as circulating tumor (CTCs) DNA), exosomes have richer number stronger biological stability, great potential in diagnosis. Thus, it has been proposed promising biomarkers early-stage...
Ligand-grafted 2D SERS substrate is applied for monitoring the evolution of CAFs in TME by specifically recognizing CD36 receptor on cytomembrane fibroblasts.
Two-dimensional (2D) nanomaterials have captured an increasing attention in biophotonics owing to their excellent optical features. Herein, 2D hafnium ditelluride (HfTe[Formula: see text], a new member of transition metal tellurides, is exploited support gold nanoparticles fabricating HfTe 2 -Au nanocomposites. The nanohybrids can serve as novel surface-enhanced Raman scattering (SERS) substrate for the label-free detection analyte with high sensitivity and reproducibility. Chemical...
Black phosphorus–polypyrrole nanosheets with superimposed NIR absorption have been fabricated as the novel nanotherapeutic agent for enhanced photothermal cancer therapy <italic>in vitro</italic> and vivo</italic>.
MoO<sub>3−x</sub> is synthesized <italic>via</italic> a one-pot hydrothermal method, with excellent stability against aging, heat, laser exposure and chemical etching.
Abstract Semiconductor nanocrystals showing surface plasmonic absorption features can be used as prospective substitutes for noble metallic nanoparticles. Herein, a creative one‐pot hydrothermal route without template is to synthesize oxygen deficiency molybdenum oxide (MoO 3‐x ) The morphologies of as‐prepared MoO nanomaterials arranged from amorphous crystalline with the reaction temperature varied 160 °C, 180 °C 200 namely quantum dots (QDs), nanosheets, and 2 nanospheres. Simultaneously,...
Metal-phenolic networks (MPNs) have been exploited to be a versatile coating film fabricate core-shell structure due their general adherent properties. Herein, gold nanocuboid (GNCB) wrapped by MPNs (GNCB at MPNs) are prepared facile encapsulation method for surface-enhanced Raman scattering (SERS) analysis. The MPN not only reshapes the electric field distribution around nanostructures but also allows substrate adsorb more analytes, both of which contribute superior SERS activity GNCB MPNs....
Tumor metabolic reprogramming requires high levels of adenosine triphosphate (ATP) to maintain treatment resistance, which poses major challenges chemotherapy and photothermal therapy. Especially, ATP promote copper ion efflux for limiting the curative effect cuproptosis. Here, an H2S-responsive mesoporous Cu2Cl(OH)3-loading chemotherapeutic cisplatin (Pt) was synthesized, final nanoparticle, Pt@Cu2Cl(OH)3-CDs (PtCuCDs), encapsulated by electrostatic action with carbon dots. PtCuCDs reacted...
<title>Abstract</title> The high level of hydrogen sulfide (H<sub>2</sub>S) in colon cancer hinders complete cure with a single therapy. However, excess H<sub>2</sub>S also offers treatment target. A multifunctional cascade bioreactor based on the H<sub>2</sub>S-responsive mesoporous Cu<sub>2</sub>Cl(OH)<sub>3</sub>-loaded hypoxic prodrug tirapazamine (TPZ), which outer layer was coated hyaluronic acid to form TPZ@Cu<sub>2</sub>Cl(OH)<sub>3</sub>-HA (TPZ@CuO) nanoparticles (NPs),...