Zhen Liang

ORCID: 0000-0001-8474-8750
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Conducting polymers and applications
  • Phytochemical Studies and Bioactivities
  • Photodynamic Therapy Research Studies
  • Nanoplatforms for cancer theranostics
  • Oil and Gas Production Techniques
  • Biochemical Acid Research Studies
  • Bone Tissue Engineering Materials
  • PI3K/AKT/mTOR signaling in cancer
  • Diet, Metabolism, and Disease
  • Saffron Plant Research Studies
  • Protein Kinase Regulation and GTPase Signaling
  • Lipid metabolism and biosynthesis
  • Corrosion Behavior and Inhibition
  • Protein Tyrosine Phosphatases
  • Metabolism, Diabetes, and Cancer
  • Electrochemical sensors and biosensors
  • Traditional Chinese Medicine Analysis
  • Analytical Methods in Pharmaceuticals
  • Regulation of Appetite and Obesity
  • Diabetes and associated disorders
  • Analytical Chemistry and Sensors
  • Magnesium Alloys: Properties and Applications
  • Drilling and Well Engineering
  • Liver Disease Diagnosis and Treatment

Sichuan University
2007-2021

Chengdu University
2020

State Council of the People's Republic of China
2020

Shenzhen Second People's Hospital
2010

Guangdong Medical College
2010

Southern Medical University Shenzhen Hospital
2007

China University of Geosciences
2006

Most chronic wounds suffer from infections, and their treatment is challenging. The usage of antibiotics may lead to bacterial resistance adverse side effects. Positively charged substances have shown promise, but applications are usually limited by certain cytotoxicity or complex synthesis. Doped polyaniline that carries a high density positive charges would be promising candidate due its good biocompatibility easy availability, interaction with bacteria has not been elucidated. Herein, the...

10.1021/acsami.1c14088 article EN ACS Applied Materials & Interfaces 2021-10-28

The strategy of novel multi-stimuli response and synergistic chemo–photodynamic therapy nanoplatform will be helpful for exploiting intelligent cancer therapy.

10.1039/d0tb00539h article EN Journal of Materials Chemistry B 2020-01-01

Abstract Magnesium alloys are biodegradable metals, but high corrosion speed and low histocompatibility after implantation still limit the application as biomedical implants. In this work, a bionic coating concept is put forward via mimicking continuous “tea stain” formation process, using layer‐by‐layer approach. Tannic acid (TA) incorporating Mg 2+ ions used to form chemical conversion on magnesium AZ31 alloy for enhanced protection favorable biocompatibility. Thermal oxidation of TA,...

10.1002/admi.201900899 article EN Advanced Materials Interfaces 2019-08-28

Nanocarriers have been an important strategy for enhancing the combination therapy of chemotherapy and photodynamic (PDT) (Chem-PDT).

10.1039/d0tb00622j article EN Journal of Materials Chemistry B 2020-01-01

The ion-pair reversed-phase HPLC method for determination of sodium tanshinone IIA sulfonate (STS) in various biological samples was the first time developed and validated, applied pharmacokinetics tissue distribution studies intravenously administrated STS mice. A linear relation found between peak area concentrations within ranges 0.1-5 micraog/ml plasma, microg/g kidney homogenate, 0.1-20 liver 0.1-1 heart, spleen lung homogenates, respectively. In plasma tissues, limit quantification...

10.1248/cpb.55.753 article EN Chemical and Pharmaceutical Bulletin 2007-01-01

Image logs provide a wide range of information about petrophysical properties and geological features reservoirs. The identification fractures by image logging is very important for the precise prediction production accurate evaluation oil gas. However, interpretations underlying from fracture occurrences, which could be crucial experts in fields, are relatively rare. Nowadays, deep learning networks, used to learn representations with diverse levels abstraction, perform well understanding...

10.30632/spwla-2022-0115 article EN SPWLA 63rd Annual Symposium Transactions 2022-06-11

Abstract This study was aimed at synthesizing and evaluating a prednisolone‐glucose derivative conjugate (PDG) that expected to increase renal biodistribution without affecting pharmacological action decrease the systemic side effects of prednisolone. The PDG designed synthesized by tethering 6‐amino‐6‐deoxy‐ D ‐glucose (a derivative) prednisolone its chemical structure confirmed 1 H NMR, 13 C LC‐MS. then subjected in vitro vivo evaluation like stability studies, biological distribution,...

10.1002/ardp.201200232 article EN Archiv der Pharmazie 2012-09-07

Background To investigate the association between phosphatase and tension homologue deleted on chromosome ten ( PTEN ) gene polymorphisms non–small‐cell lung cancer (NSCLC) further identify whether these influence serum levels. Methods A total of 152 NSCLC patients 124 healthy controls were included in study. rs11202586 (T > C) rs1903858 (A G) detected using multiple single‐base extension technique (SNaPshot). The levels determined an enzyme‐linked immunosorbent assay (ELISA) kit. Results...

10.1002/jcla.23328 article EN cc-by Journal of Clinical Laboratory Analysis 2020-06-15
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