A5038272489- Colorectal Cancer Screening and Detection
- Prostate Cancer Treatment and Research
- Genetic factors in colorectal cancer
- Genetic Associations and Epidemiology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cancer Genomics and Diagnostics
- Prostate Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Cultural Competency in Health Care
- Cancer Immunotherapy and Biomarkers
- Glycosylation and Glycoproteins Research
- Dermatology and Skin Diseases
- Hemoglobinopathies and Related Disorders
- Immune Cell Function and Interaction
- Pediatric health and respiratory diseases
- Noise Effects and Management
- Genital Health and Disease
- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Epigenetics and DNA Methylation
- Erythrocyte Function and Pathophysiology
- Cancer-related molecular mechanisms research
- Allergic Rhinitis and Sensitization
- Workplace Violence and Bullying
- RNA modifications and cancer
The University of Sydney
2022-2025
University of South Australia
2018-2023
Flinders University
2018
Bushehr University of Medical Sciences
2014-2017
Germline testing for prostate cancer is on the increase, with clinical implications risk assessment, treatment, and management. Regardless of family history, NCCN recommends germline patients metastatic, regional, very-high-risk localized, high-risk localized cancer. Although African ancestry a significant factor aggressive cancer, due to lack available data no criteria have been established ethnic minorities.Through deep sequencing, we interrogated 20 most common panel genes in 113 Black...
African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common variants contributing to multiethnic polygenic score, with rare focused on panel roughly 20 pathogenic genes. Based this knowledge, we are unable determine or differentiate status interrogating whole genome data 113 Black South men. To further assess potentially functional variant...
Abstract Prostate cancer (PCa) is highly heritable, with men of African ancestry at greatest risk and associated lethality. Lack representation in genomic data means germline testing guidelines exclude for Africans. Established that structural variations (SVs) are major contributors to human disease prostate tumourigenesis, their role under-appreciated familial therapeutic testing. Utilising clinico-methodologically matched deep-sequenced whole-genome 113 versus 57 European PCa patients, we...
Discrimination in education is commonly associated with face-to-face interactions between teachers and students. However, e-learning environments can also foster discrimination. Despite existing research on discrimination traditional education, limited studies address this issue virtual particularly nursing education. This study aimed to explore the factors contributing perceived among midwifery students, focusing underlying causes conditions that shape these experiences. A qualitative...
Prostate cancer shows significant racial disparity, with men of African ancestry disproportionately impacted. While prostate health disparity studies focus on elucidating the contributing socioeconomic, lifestyle, environmental, biological and underlying genetic factors, genome sequencing is helping to reduce burden through disease stratification treatment. Sub-Saharan Africa has, till now, been excluded from these benefits. The new Cancer Precision Health Africa1K Equity Research Outcomes...
Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk factors are lacking within the continent and as such exclude for ancestral diversity. Here, we investigate series of epidemiological demographic lifestyle 1387 men recruited part multi-ethnic Southern Cancer Study (SAPCS). We found poverty be decisive factor disease grade age diagnosis, other notably PCa...
Background Although survival from colorectal cancer (CRC) has improved substantially in recent decades, people with advanced age still have a high likelihood of mortality this disease. Nonetheless, few studies investigated how stage, subsite and comorbidities contribute collectively to poor prognosis older CRC. Here, we decided explore the association measures other variables influenced association. Methods Using linkage several administrative datasets, risk death among CRC cases during...
Abstract Background Although the need for justice and elimination of injustice (or discrimination) is now a universally accepted principle, discrimination still an unpleasant experience many nursing students. This study aimed to explain experiences students educational find out main factors that cause this feeling. Methods qualitative conducted in faculty Shahr-e-Kord Iran university medical science (IUMS) Iran. Twelve were selected by purposeful sampling method data collected through...
Abstract African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet, genetic studies have largely been conducted outside the context of Sub-Saharan Africa, identifying 278 common variants contributing to multiethnic polygenic score, with rare focused on panel roughly 20 pathogenic genes. Based this knowledge, we were unable determine or differentiate status interrogating whole genome data 113 Black South men. To further assess potentially functional variant...
Human epidermal growth factor receptor-2 is an important and prognostic factors one of the most targeted proteins in breast cancer's therapy. There no globally accepted method for determining its status. Here, we aimed to evaluate immunohistochemistry validity predicting HER-2 status by Fluorescence situ hybridization investigate some clinicopathological variables association with amplification. A total 190 2+ 3+ (IHC) invasive cancer cases were enrolled this study. (FISH) was performed...
IntroductionAustralians have a high incidence of Colorectal cancer (CRC) and it is the second leading cause death. CRC patients experience more comorbid conditions such as diabetes heart diseases than expected from population norms. It anticipated that older with will even comorbidities.
 ApproachData South Australia Cancer Registry were linked hospital inpatient separations (public private) Pharmaceutical Benefit Scheme data to acquire detailed dataset in Australia. We investigated...
<title>Abstract</title> Prostate cancer (PCa) is highly heritable, with men of African ancestry at greatest risk and associated lethality. Lack representation in genomic data means germline testing guidelines exclude for men. Established that structural variations (SVs) are major contributors to human disease prostate tumourigenesis, their role under-appreciated familial therapeutic testing. Utilising a clinico-methodologically matched (n = 113) <italic>versus</italic> European 57)...
Abstract Background Advanced age is associated with decreased likelihood of colorectal cancer treatment. Here, we investigated the extent to which comorbidities are accountable for this lesser Methods Using population‐based datasets, pattern care among CRC cases in South Australia during 2004–2013 was investigated. Models were used investigate associations each treatment type, and differences these explored by comorbidity site. Results The presence a significantly weaker relationship surgery...
Abstract Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk factors are lacking within the continent and as such exclude for ancestral diversity. Here, we investigate series of epidemiological demographic lifestyle 1,387 men recruited part multi-ethnic Southern Cancer Study (SAPCS). We found poverty be decisive factor disease grade age diagnosis, other notably...
Background: While age and stage at diagnosis are known to affect treatment choices survival from colorectal cancer (CRC), few studies have investigated the extent which these effects influenced by comorbidity. In this study, we describe occurrence of comorbidity in CRC cases South Australia associations with age, age-stage relationship.Methods: The Australian Cancer Registry (SACR) provided data (C18-C20, ICD-10) for 2004-2013 diagnoses. were linked drawn hospital records health insurance...
Abstract Background Virtual and e-learning have taken on a more prominent role since the inception of coronavirus. One disadvantages that are less addressed is feeling discrimination in this type education. So, study aims to explain nursing students' experiences educational Methods This qualitative conducted Isfahan midwifery faculty Iran 2021. Thirteen students were selected by purposeful sampling method interviewed data collected through face-to-face in-depth interviews with...