A5011681963- Radiopharmaceutical Chemistry and Applications
- Chronic Lymphocytic Leukemia Research
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Thyroid Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Hepatitis C virus research
- Iron Metabolism and Disorders
- Viral Infections and Immunology Research
- Monoclonal and Polyclonal Antibodies Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Immunotherapy and Immune Responses
- Epigenetics and DNA Methylation
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Infective Endocarditis Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Myopathies and Dermatomyositis
- Complementary and Alternative Medicine Studies
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
- Resilience and Mental Health
- Cancer Immunotherapy and Biomarkers
- Ocular Diseases and Behçet’s Syndrome
- Thyroid and Parathyroid Surgery
- Thyroid Disorders and Treatments
Bushehr University of Medical Sciences
2012-2022
Imam Reza International University
2020
Abstract In recent years, lutetium-177 (177Lu)-labeled prostate-specific membrane antigen (PSMA)-617 has become a promising new therapeutic agent in patients with metastatic castration-resistant prostate cancer (mCRPC). this study, we report on an early experience of177Lu-PSMA therapy evaluation of its efficacy and safety mCRPC patients. Twenty-one mean age 70.3 ± 9.6 (54–88)-year-old were treated one to four cycles (median two cycles) administered activity 3.7–29.6 GBq (mean 15.4 GBq). A...
<b><i>Objective:</i></b> This study was conducted to determine the prevalence and genotype distribution of hepatitis C virus (HCV) infection among patients with type 2 diabetes mellitus (DM). <b><i>Subjects Methods:</i></b> We included 556 consecutive confirmed DM attending Diabetic Clinic Bushehr University Medical Sciences 733 nondiabetic subjects as controls. Serum levels fasting blood sugar (FBS), alanine transaminase (ALT), aspartate...
Behcet's disease (BD) is a multisystem of unknown etiology. There are several clues which may indicate an ethiopathogenesis role for Helicobacter pylori infection in this disease. In case control study out patient department, 48 patients with BD were compared to age, sex matched controls regarding presence H. by serology and urea breath test (UBT). Ongoing was more prevalent among using result UBT odds ratio 3.1 (95% CI: 1.34 – 7.26, PV < 0.001). have the pathogenesis BD.
Toxoplasmosis is a life-threatening infection in organ transplant recipients, people receiving corticosteroid or radiation therapy, with malignancies, and AIDS patients.The current study aimed to determine the prevalence of toxoplasmosis patients chemotherapy for malignancies Bushehr province southwest Iran.Blood samples were taken from 86 who continuously referred center evaluated by ELISA anti-Toxoplasma IgG IgM antibodies. Moreover, blood buffy coat each sample was assessed polymerase...
Purpose This pilot study tested the principle that 177 Lu-DOTATATE may be applied to patients with high-grade gliomas (HGGs) are either inoperable or refractory standard conventional treatments and also assessed whether this approach could a viable therapeutic plan in dilemma. Methods In prospective study, 16 subjects experiencing HGGs were included. All checked for somatostatin receptor expression on tumors. The treated 1 4 cycles of IV Lu-DOTATATE. primary end point was radiological...
Cancer and cardiovascular disease are the most significant causes of morbidity mortality worldwide. Although cancer survival rate has increased due to improved treatment approaches, especially targeted therapy, some side effects such as cardiotoxicity decrease efficiency clinical outcome. Radiation therapy chemotherapy have a long-established history potential cardiotoxic effects. A new multi-disciplinary translational field known cardio-oncology been developed for identification,...
The present case demonstrates a diffuse intense hepatic and, to lesser degree, spleen, Tc-99m MDP uptake on routine bone scintigraphy resembling liver-spleen imaging. A 49-year-old female with history of anaplastic plasma cell tumor and suffering from pain was referred for evaluate possible metastases. showed spleen Furthermore, significantly diminished there were no abnormal foci throughout the skeleton. an suggests presence amyloidosis.
Background: TP53 tumor suppressor gene participates in several pathways involving carcinogenesis such as cell cycle control, DNA repair, and apoptosis. A common SNP (guanine/cytosine nucleotide substitution at codon 72), rs1042522, affects the function of p53 protein may influence behavior response to environmental carcinogens. Objectives: This study investigates association between 72 polymorphisms, tobacco smoking, breast cancer risk southern Iranian women from Bushehr. Methods:...
Docetaxel is a clinically well established antimitotic chemotherapy medication. Labeled docetaxel indications are breast cancer, gastric head and neck non-small cell lung prostate cancer.This Phase IV study to evaluate the safety profile of (Alvotere; NanoAlvand, Iran) in Iranian patients diagnosed with different types cancers receiving regimens docetaxel.Patients who received Alvotere as part their regimen were enrolled this IV, observational, multicenter, open-label study. was...
Background This study was conducted to evaluate the clinical efficacy and safety of peptide receptor radionuclide therapy (PRRT) using 177 Lu-DOTA0-Tyr3-octreotate (DOTATATE) in patients with neuroendocrine tumors (NETs). Methods Sixteen pathologically verified NETs including eight females males were enrolled this study. Before PRRT, underwent 68 Ga-DOTATATE positron emission tomography/computed tomography or 99m Tc-octreotide scintigraphy for evaluation somatostatin expression. Response...
Abstract BackgroundWe decided to evaluate the clinical efficacy and safety of peptide receptor radionuclide therapy (PRRT) with 177-DOTATATE in patients neuroendocrine tumors (NETs).MethodsSixteen pathologically verified NETs including eight females males were enrolled this study. Before PRRT for evaluation somatostatin expressing, underwent 68Ga-DOTATATE PET-CT or 99mTc-octreotide scintigraphy. The treatment response was assessed according criteria solid (RECIST) which classified into...