Malihe Aghasizadeh

ORCID: 0000-0001-8562-360X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Cancer-related molecular mechanisms research
  • Cancer, Lipids, and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease
  • Adipokines, Inflammation, and Metabolic Diseases
  • Antioxidant Activity and Oxidative Stress
  • Lipoproteins and Cardiovascular Health
  • Cholesterol and Lipid Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Curcumin's Biomedical Applications
  • Medicinal Plants and Bioactive Compounds
  • Fatty Acid Research and Health
  • Vitamin C and Antioxidants Research
  • Cardiovascular Health and Risk Factors
  • MicroRNA in disease regulation
  • Natural Antidiabetic Agents Studies
  • Gout, Hyperuricemia, Uric Acid
  • Reproductive System and Pregnancy
  • Culinary Culture and Tourism
  • Blood properties and coagulation
  • Biochemical effects in animals
  • Birth, Development, and Health
  • Antioxidants, Aging, Portulaca oleracea

Mashhad University of Medical Sciences
2016-2025

Birjand University of Medical Sciences
2020-2022

Brighton and Sussex Medical School
2022

Razi Hospital
2022

Shahrekord University of Medical Sciences
2022

Imam Reza Hospital
2017

Abstract Background Previous studies have reported insulin resistance (IR) to be associated with hyperuricemia. In this study, we aimed assess the possible associations between empirical dietary index for IR (EDIR), lifestyle (ELIR), and non-insulin-based surrogates (triglyceride–glucose (TyG) index, triglyceride-to-high-density-lipoprotein-cholesterol (TG/HDL-C) ratio, metabolic score (METS-IR) TyG body mass (TyG-BMI)) hyperuricemia in an Iranian population. Methods cross-sectional 6457...

10.1186/s12937-023-00904-2 article EN cc-by Nutrition Journal 2024-01-03

Urbanization is expanding in Iran, leading to the emergence of three distinct socio-geographical areas: urban, rural, and suburban areas. These different areas may exhibit significant variations dietary patterns. This study investigates association between people's place residence their consumption food groups. utilized data from Iran's Food Nutrition Surveillance System (FNS). A total 1697 participants were randomly recruited rural (N = 568), urban 561) regions across Iran. Their intake was...

10.1186/s12889-024-21211-3 article EN cc-by-nc-nd BMC Public Health 2025-01-15

Following up with recovered coronavirus disease 2019 (COVID-19) patients is necessary. Given the importance of psychological function accompanied by significant effects food quality, we want to examine association between quality score (FQS) and mental disorders among COVID-19 patients. This case-control study was performed on 246 eligible adults. A validated frequency questionnaire (FFQ) used evaluate dietary intake. We using Depression Anxiety Stress Scales, Insomnia Severity Index,...

10.7762/cnr.2025.14.1.17 article EN Clinical Nutrition Research 2025-01-01

Abstract A randomized clinical trial high‐density lipoprotein (HDL) cholesterol uptake capacity (CUC) is reduced in patients with metabolic syndrome (MetS). We have assessed the effect of crocin supplementation on HDL CUC MetS. Forty‐four subjects MetS were randomly allocated to one two groups: group received placebo and other at a dose 30 mg (two tablets 15 per day) for 8 weeks. Serum biochemical parameters measured using an AutoAnalyzer BT3000 (BioTechnica). The modified method cell free,...

10.1002/biof.1783 article EN BioFactors 2021-10-05

The efficiency of high-density lipoprotein (HDL) to efflux cholesterol contributes the reverse transport (RCT) pathway as one HDL's proposed functions and depends on ability HDL uptake cholesterol. We aimed investigate capacity (CUC) by a newly developed assay in samples from MASHAD (Mashhad Stroke Heart Atherosclerotic Disorders) cohort study.The study population comprised 153 individuals CVD diagnosed specialist cardiologist, over 6 years follow-up, 350 subjects without CVD. used modified...

10.1002/jcla.23770 article EN Journal of Clinical Laboratory Analysis 2021-05-24

Diabetes mellitus (DM) is a major health problem with an increasing global prevalence. It usually associated imbalance between pro-oxidant mechanisms and antioxidant defenses, contributing to oxidative-stress, this leads increased susceptibility endothelial dysfunction, atherosclerosis, insulin-resistance impaired-pancreatic β-cell function.We have assessed the Prooxidant-antioxidant balance (PAB) anti-hemolytic effect of Thuja orientalis L using PAB assay analysis hematological markers.The...

10.2174/1874467210666170404112211 article EN Current Molecular Pharmacology 2017-04-06

The pathogenesis of metabolic syndrome (MetS) complications involves the excessive production of<br />reactive oxygen species, inflammation, and endothelial dysfunction. Due to Lycopene, a highly unstable structure and<br />its significant effects on modulating system, there is strong need for formula that can increase its<br />stability. aim this study was develop an approach encapsulating Lycopene investigate its on<br />inflammatory markers, oxidative stress, liver enzymes in patients...

10.22074/cellj.2023.2006158.1353 article EN PubMed 2023-12-31

The Angiopoietin-like 3 (ANGPTL3) gene has been reported to be associated with cardiovascular risk. This study is designed compare the genetic variant (rs1748195) of ANGPTL3 and presence a coronary artery occlusion >50% in Iranian nation.

10.1002/mgg3.2105 article EN cc-by-nc Molecular Genetics & Genomic Medicine 2022-11-23

Abstract Background Loss‐of‐function (LOF) variants of the angiopoietin‐like 3 (ANGPTL3) gene are reported to be associated with serum triglyceride (TG) and high‐density lipoprotein cholesterol (HDL‐C) concentrations thereby affect risk cardiovascular disease (CVD). Objective In present study, we examined association rs10789117 in ANGPTL locus CVD group people who were part Mashhad‐Stroke Heart‐Atherosclerotic‐Disorders (MASHAD) cohort. Methods One thousand two healthy individuals enrolled...

10.1002/mgg3.2418 article EN cc-by-nc-nd Molecular Genetics & Genomic Medicine 2024-04-01

Metabolic syndrome (Mets) is a common metabolic disorder in which hypoadiponectinemia one of the consequences for body caused by inflammation, and vitamin D may help improve inflammatory symptoms. LncRNAs (long non-coding RNA) play several different regulatory roles body. The goal this study was to see how adding milk affected levels adiponectin lncRNAs serum people with Mets.This clinical trial conducted on staff students between ages 30 50 at Mashhad University Medical Sciences met...

10.1186/s13098-023-00979-1 article EN cc-by Diabetology & Metabolic Syndrome 2023-01-18

Coronavirus disease (COVID-19) is an infectious that can spread very rapidly with important public health impacts. The prediction of the factors related to patient's diseases helpful care workers. aim this research was select critical feature relationship between demographic, biochemical, and hematological characteristics, in patients without COVID-19 infection.A total 13,170 participants age range 35-65 years were recruited. Decision Tree (DT), Logistic Regression (LR), Bootstrap Forest...

10.1186/s12879-023-08676-0 article EN cc-by BMC Infectious Diseases 2023-12-21

Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with therapy referring to heart clinic of Birjand recruited. Patients classified examined LDL-C values proportion reaching targets according American Association Clinical Endocrinologists guideline. Three patterns use (high/moderate/low-intensity therapy) in all attainments groups have been demonstrated. Over...

10.1038/s41598-021-90228-0 article EN cc-by Scientific Reports 2021-05-24

We have investigated the association between markers of renal function [serum urea nitrogen, creatinine, and estimated glomerular filtration rate (eGFR)] age lipid profile in an Iranian population sample 4,567 subjects.Serum creatinine together with anthropometric parameters were determined all subjects. eGFR was calculated using modification diet disease formula.Serum nitrogen increased (p < .05), this relationship also more pronounced men compared to women. Increased levels these...

10.3109/19390211.2016.1155686 article EN Journal of Dietary Supplements 2016-04-14

Metabolic syndrome (MetS) is a common clustering of cardiovascular risk factors associated with increased inflammation. Long non-coding RNA (LncRNA) are involved in many the body's metabolic activities, including Vitamin D may play vital role preventing factors. This study aimed to evaluate status inflammation and expression LncRNA their relationship serum vitamin levels patients syndrome.This cross-sectional included staff Mashhad University Medical Sciences students between 30 50 years old...

10.1002/mnfr.202200144 article EN Molecular Nutrition & Food Research 2022-11-01

Background: Premature Ovarian Insufficiency (POI) is associated with infertility. Little known about the potential circulating biomarkers that could be used to predict POI. We have investigated possible association between white and red blood cells, platelet indices, eight established single nucleotide polymorphisms (SNPs) POI risk. Methods: 117 women premature menopause (PM) 183 healthy without a history of before age 40 were recruited for this study. The tetra-primer amplification...

10.2174/011871529x297081240613075328 article EN Cardiovascular & Haematological Disorders - Drug Targets 2024-06-01
Coming Soon ...