A5022276754- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- T-cell and Retrovirus Studies
- Long-Term Effects of COVID-19
- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Animal Disease Management and Epidemiology
- Dementia and Cognitive Impairment Research
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Stroke Rehabilitation and Recovery
- Systemic Lupus Erythematosus Research
- Neurological Disease Mechanisms and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Neurological Disorders and Treatments
- Vector-Borne Animal Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Blood Pressure and Hypertension Studies
- Global Public Health Policies and Epidemiology
- Venous Thromboembolism Diagnosis and Management
- Climate Change and Health Impacts
- Nutrition and Health in Aging
- Atherosclerosis and Cardiovascular Diseases
- Heat shock proteins research
- Retinal and Optic Conditions
Western University
2016-2025
Ghaem Hospital
2013-2023
Mashhad University of Medical Sciences
2014-2023
London Health Sciences Centre
2016-2021
Robarts Clinical Trials
2021
Thrombosis and Atherosclerosis Research Institute
2019
The University of Texas Health Science Center at San Antonio
2018
Wayne State University
2018
Dr. Everett Chalmers Regional Hospital
2017
Dalhousie University
2017
The relative contributions of vascular and degenerative pathology to dementia are unknown. We aim quantify the proportion explained by potentially preventable lesions.We systematically searched for population-based cohorts before February 2017 reporting clinicopathological data individuals with without dementia. calculated summary absolute risk comparing subjects pathology.We identified 10 studies comprising 2856 subjects. Vascular-type mixed respectively two three times more likely in...
Oxidative stress is thought to play an important role in atherogenesis. The statin group of cholesterol-lowering drugs have been shown reduce cardiovascular events and possess antioxidant properties. We aimed assess the effects simvastatin on a novel measure prooxidant-antioxidant balance (PAB) dyslipidemic patients. PAB assay can prooxidant burden capacity simultaneously one assay, thereby giving redox index. treated 102 individuals with simvastatin, or placebo double-blind, cross-over,...
BackgroundThe interaction between coronavirus disease 2019 (COVID-19) and non-communicable diseases may increase the global burden of disease. We assessed association COVID-19 with ageing diseases.MethodsWe extracted data regarding disease, particularly cardiovascular deaths, disability-adjusted life years (DALYs), healthy expectancy (HALE) from Global Burden Disease Study (GBD) 2017. obtained confirmed cases, tests Our World in Data database as May 28, 2020. Potential confounders pandemic...
Background Hypertension ( HTN ) is a risk factor for stroke, renal failure, and cardiovascular disease. The association between biochemical hematological parameters with high blood pressure may provide more precise approach to prediction conferred by in these patients. Objective aim of current study was explore whether are associated cohort 7‐year follow‐up. Materials Methods A total 9808 individuals were enrolled recruited as part the Mashhad Stroke Heart Atherosclerotic Disorders MASHAD...
Measurement of total-plaque-area (TPA) is important for determining long term risk stroke and monitoring carotid plaque progression. Since delineation plaques required, a deep learning method can provide automatic segmentations TPA measurements; however, it requires large datasets manual annotations training with unknown performance on new datasets. A UNet++ ensemble algorithm was proposed to segment from 2D ultrasound images, trained three small (n = 33, 34 subjects) tested 44 subjects the...
Vessel-wall-volume (VWV) is an important three-dimensional ultrasound (3DUS) metric used in the assessment of carotid plaque burden and monitoring changes atherosclerosis response to medical treatment. To generate VWV measurement, we proposed approach that combined a voxel-based fully convolution network (Voxel-FCN) continuous max-flow module automatically segment media-adventitia (MAB) lumen-intima boundaries (LIB) from 3DUS images. Voxel-FCN includes encoder consisting general 3D CNN...
Human T-lymphotropic virus type 1 (HTLV-I) is an important global health problem in the world mainly endemic areas of HTLV-I infection. It was previously reported that Mashhad, northeastern Iran, a new region HTLV-I. The aim this study to examine prevalence and phylogenetic analysis Sabzevar, located southeast Mashhad. In cross-sectional 1445 individuals were selected by multistage cluster sampling. Serum samples screened for anti-HTLV-I antibody using enzyme-linked immunosorbent assay...
The prevalence of metabolic syndrome (MetS) is increasing globally. It associated with a significant risk developing type 2 diabetes mellitus and cardiovascular disease.The relationship between adherence to several different dietary patterns the presence MetS was explored in an Iranian population sample 5764 subjects.We observed that 13% 18% men women, respectively. There were three main patterns: first pattern characterized by protein, carbohydrate, starch, glucose, fructose, sucrose,...
Abstract Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors represent a novel approach for reducing cholesterol and, accordingly, the burden of atherosclerosis. However, limited data are available regarding possible effects PCSK9 on atherosclerotic plaque. To evaluate efficacy in carotid plaque progression individuals with high‐risk disease. We used total area (TPA) to assess Ultrasound imaging was acquired before and after initiation inhibitor therapy. selected cases...
Objective The global prevalence of metabolic syndrome (MetS) appears to be increasing and the impact this condition on potential comorbidities such as cardiovascular disease is high. Chronic kidney (CKD) also a comorbidity MetS but method screening for somewhat controversial. Thus, predictive markers that can predict risk developing CKD are warranted identification patients with at an increased risk. Research methods/patients We investigated occurrence in 6492 individuals, either or without...
Generalized anxiety disorder (GAD) in elderly people is common, but few systematic studies regarding the best treatments have been performed. The aim of present study was to evaluate efficacy and safety sertraline buspirone treatment patients with GAD.Based on selection criteria, 46 were recruited who met DSM-IV criteria for GAD. Patients randomly assigned (50-100 mg/day) or (10-15 8 weeks a single-blind trial. primary outcome measure used Hamilton Rating Scale Anxiety (HRSA).Both had...