Salvador Cruz‐Flores
A5076579473- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Palliative Care and End-of-Life Issues
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- Cardiac Arrest and Resuscitation
- Neurological Disease Mechanisms and Treatments
- Peripheral Neuropathies and Disorders
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- Neurological and metabolic disorders
- Neurological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Neurological disorders and treatments
- Cardiac Imaging and Diagnostics
- Blood Coagulation and Thrombosis Mechanisms
- Coronary Interventions and Diagnostics
- Autoimmune Neurological Disorders and Treatments
- Cardiovascular Syncope and Autonomic Disorders
Texas Tech University Health Sciences Center
2016-2025
Texas Tech University
2016-2025
The University of Texas at El Paso
2019-2024
University of Miami
2010-2023
University of California, San Francisco
2021-2023
Medical University of South Carolina
2021-2023
The University of Texas Southwestern Medical Center
2021-2023
Wake Forest University
2023
University of Southern California
2023
University of Alabama at Birmingham
2023
Our goal is to describe the effect of race and ethnicity on stroke epidemiology, personal beliefs, access care, response treatment, participation in clinical research. In addition, we seek determine state knowledge main factors that may explain disparities with identifying gaps guide future The intended audience includes physicians, nurses, other healthcare professionals, policy makers.Members writing group were appointed by American Heart Association Stroke Council Scientific Statement...
Induced hypothermia is a promising neuroprotective therapy. We studied the feasibility and safety of thrombolysis after acute ischemic stroke.Intravenous Thrombolysis Plus Hypothermia for Acute Treatment Ischemic Stroke (ICTuS-L) was randomized, multicenter trial intravenous tissue plasminogen activator in patients treated within 6 hours stroke. Enrollment stratified to treatment time windows 0 3 hours. Patients presenting symptom onset received standard dose alteplase were randomized...
Background and Purpose— To determine the hospital mortality rates associated with elective surgical clipping endovascular coiling of unruptured intracranial aneurysms. Methods— We identified a cohort patients electively admitted to US hospitals diagnosis aneurysm from National Inpatient Sample database for years 2000 through 2006. Patient demographics, hospital-associated complications, in-hospital were compared among treatment groups. A multivariate logistic regression analysis was used...
Background and Purpose— Patients with intracerebral hemorrhage intraventricular have a reported mortality of 50% to 80%. We evaluated clot lytic treatment strategy for these patients in terms mortality, ventricular infection, bleeding safety events, its effect on the rate lysis. Methods— Forty-eight were enrolled at 14 centers randomized 3 mg recombinant tissue-type plasminogen activator (rtPA) or placebo. Demographic characteristics, severity factors, outcomes (mortality, bleeding),...
Therapeutic hypothermia is a potent neuroprotectant approved for cerebral protection after neonatal hypoxia-ischemia and cardiac arrest. acute ischemic stroke safe feasible in pilot trials. We designed study protocol to provide safer, faster therapeutic patients.Safety procedures 4°C saline infusions cooling were added the ICTuS trial (Intravascular Cooling Treatment of Stroke) protocol. A femoral venous intravascular catheter intravenous recombinant tissue-type plasminogen activator...
The purpose of this study was to evaluate the mortality rates associated with cerebral venous-sinus thrombosis in a large national sample.A cohort patients identified from National Inpatient Sample database for years 2000 2007. According International Classification Diseases, 9th Revision, Clinical Modification codes, is categorized into pyogenic and nonpyogenic groups. Multivariate logistic regression analysis used assess covariates hospital mortality.Among 3488 patients, overall rate...
Hemicraniectomy and Durotomy Upon Deterioration From Infarction-Related Swelling Trial (HeADDFIRST) was a randomized pilot study to obtain information necessary design Phase III trial evaluate the benefit of surgical decompression for brain swelling from large supratentorial cerebral hemispheric infarction.All patients with stroke were screened eligibility (age 18-75 years, National Institutes Health Stroke Scale≥18 Item 1a<2 [responsive minor stimulation], CT demonstrating unilateral,...
In 1974, Dr. Balfour Mount introduced the term "palliative" from Latin word palliare—"to wrap in comfort"—as a description of an approach that supports patients by focusing on improving their quality life through symptom control, both physical and psychological, rather than diagnosis treatment underlying disease. He sought to separate this part supportive care emerging hospice movement, which was focused solely end life. minds many physicians as well lay public, palliative is often seen...
<b>Objective: </b> We sought to demonstrate that isolated episodes of vertigo can be the only manifestation vertebrobasilar ischemia. Background: Isolated persistent is classically ascribed labyrinthine disorders and rarely considered reflect Methods: retrospectively analyzed all records Saint Louis University Stroke Registry between January 1, 1992 September 1993. set out identify those patients discharged with a diagnosis transient ischemic attack (TIA) in system. reviewed their clinical...
Background. Despite the proven efficacy of acyclovir (ACV) therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality. Among patients with HSE treated ACV, mortality rate is approximately 14%–19%. survivors, 45%–60% have neuropsychological sequelae at 1 year. Thus, improving therapeutic approaches remains a high priority. Methods. Following completion standard course intravenous 87 adult (confirmed by positive polymerase chain reaction [PCR] for virus...
Background and Purpose— Inflammatory biomarkers predict incident recurrent cardiac events, but their relationship to stroke prognosis is uncertain. We hypothesized that high-sensitivity C-reactive protein (hsCRP) predicts ischemic after recent lacunar stroke. Methods— Levels of Markers in the Treatment Stroke (LIMITS) was an international, multicenter, prospective ancillary biomarker study nested within Secondary Prevention Small Subcortical Strokes (SPS3), a phase III trial patients with...