A5101900054- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Pharmacogenetics and Drug Metabolism
- Fibroblast Growth Factor Research
- Cardiovascular Health and Risk Factors
- Pharmaceutical studies and practices
- Magnesium in Health and Disease
- Gastroesophageal reflux and treatments
- Complement system in diseases
- Viral Infections and Outbreaks Research
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Pain Management and Opioid Use
- Healthcare Systems and Reforms
- Platelet Disorders and Treatments
- COVID-19 and healthcare impacts
- Dialysis and Renal Disease Management
- Potassium and Related Disorders
- Medication Adherence and Compliance
- Helicobacter pylori-related gastroenterology studies
- Opioid Use Disorder Treatment
- Acute Kidney Injury Research
- Cardiovascular Function and Risk Factors
- Advances in Oncology and Radiotherapy
- Esophageal and GI Pathology
Optum (United States)
2020-2023
National Institute of Neurological Disorders and Stroke
2023
University of California, Davis
2023
University of Minnesota
2013-2023
University of Mississippi Medical Center
2023
University of North Carolina at Chapel Hill
2023
Jackson Memorial Hospital
2023
Mayo Clinic in Arizona
2017-2021
University of Glasgow
2016-2017
Centers for Disease Control and Prevention
2017
Noninvasive quantification of myocardial fibrosis in end-stage renal disease is challenging. Gadolinium contrast agents previously used for cardiac magnetic resonance imaging (MRI) are contraindicated because an association with nephrogenic systemic fibrosis. In other populations, increased native T1 times on MRI have been shown to be a surrogate marker We applied this method 33 incident hemodialysis patients and 28 age- sex-matched healthy volunteers who underwent at 3.0T. Native relaxation...
Studies on the association between proton pump inhibitor (PPI) use and dementia report mixed results do not examine impact of cumulative PPI use. We evaluated associations current risk incident in Atherosclerosis Risk Communities (ARIC) Study.
The Joint External Evaluation (JEE), a consolidation of the World Health Organization (WHO) International Regulations 2005 (IHR 2005) Monitoring and Framework Global Security Agenda country assessment tool, is an objective, voluntary, independent peer-to-peer multisectoral country's health security preparedness response capacity across 19 IHR technical areas. WHO approved standardized JEE tool in February 2016. process wholly transparent; countries request are encouraged to make its findings...
Hepatocyte growth factor (HGF) is positively associated with ischemic and hemorrhagic stroke risk factors. However, understanding the relation between HGF in its infancy. Therefore, we sought to examine association of circulating incident using data from MESA (Multi-Ethnic Study Atherosclerosis). We hypothesized that would be an increased stroke.
Variation in the CYP2D6 gene may affect response to opioids both poor and ultrarapid metabolizers, but data demonstrating such associations have been mixed, impact of variants on toxicity-related symptoms (e.g., nausea) is unclear. Therefore, we examined association between phenotype pain control or other adverse related use a sample primary care patients.We identified all patients Mayo Clinic RIGHT Protocol who were prescribed an opioid medication July 01, 2013 June 30, 2015, categorized...
<h3>Objective</h3> To determine if hepatocyte growth factor (HGF), a promising biomarker of coronary heart disease (CHD) given its release into circulation in response to endothelial damage, is associated with subclinical and clinical CHD racial/ethnic diverse population. <h3>Methods</h3> HGF was measured 6738 participants the Multi-Ethnic Study Atherosclerosis (MESA). Highest mean values (pg/mL) were observed Hispanic, followed by African, non-Hispanic white, then Chinese Americans....
We investigated the association between adverse events (AEs) suspected to be immune-related and health care resource utilization, costs, mortality among patients receiving programmed cell death 1/programmed ligand 1 immune checkpoint inhibitor (ICI) monotherapy for urothelial carcinoma, renal non-small lung cancer, or Merkel carcinoma.We conducted a retrospective cohort study using medical pharmacy claims enrollment information from U.S. commercial Medicare Advantage with Part D enrollees in...
Objective. Previous studies have speculated that the higher stroke incidence rate (IR) in blacks compared with whites may be due, part, to risk factors exerting a more adverse effect among than whites. To determine whether such racial differences exist we prospective associations between novel, traditional, and emerging whites.Design. Baseline characteristics on factor levels were obtained 15,407 participants from Atherosclerosis Risk Communities Study. Stroke was ascertained 1987 2008....
Goals: The goal of this study was to evaluate whether proton pump inhibitor (PPI) use is cross-sectionally associated with hypomagnesemia and mediates the prospective association between PPIs cardiovascular disease (CVD) risk. Background: Use has been hypomagnesemia, primarily in case reports or within insurance databases. Both PPI low serum magnesium (Mg) have modestly higher CVD Yet, interrelation Mg relation risk unclear. Study: 4436 Atherosclerosis Risk Communities participants without...
BACKGROUND: Chemotherapy-induced neutropenia increases the risk of febrile (FN) and infection with resultant hospitalizations, substantial health care resource utilization (HCRU) costs. Granulocyte-colony stimulating factor (GCSF) is recommended as primary prophylaxis for chemotherapy regimens having more than a 20% FN. Yet, intermediate-risk (10%-20%) regimens, it should be considered only patients 1 or clinical factors (RFs) It unclear whether FN being optimally implemented. OBJECTIVE: To...
Abstract Background The cellular adhesion pathway has been suggested as playing an important role in the pathogenesis of atrial fibrillation (AF). However, prior studies that have investigated proteins risk AF limited number were studied and ethnic racial diversity study population. Therefore we aimed to associations fifteen with incident a large, diverse Methods Multi-Ethnic Study Atherosclerosis participants from four races/ethnicities (n = 2504) protein levels measured followed for 253)....
Total (or near total) thyroidectomy (TE) followed by radioiodine ((131)I) ablation (RIA) of residual thyroid tissue is considered to be the ideal treatment for differentiated carcinoma. However, actual guideline DGN (German Society Nuclear Medicine) recommends so-called papillary micro-carcinoma (PMC) no further therapeutic strategy (no complete TE, (131)I-ablation remaining lobe). PMC has been defined as carcinoma measuring 1 cm (T1) in maximal diameter according World Health Organization...
Introduction: Although there is substantial evidence that physical activity reduces risk of cardiovascular disease (CVD), the few studies included African Americans offer inconclusive and did not study stroke heart failure separately. Objective: We examined, in Caucasians Atherosclerosis Risk Communities (ARIC), association with CVD incidence (n=1,039) its major components - (n=350), (n=633), coronary (n=442) over a follow-up period 21 years. Methods: ARIC population-based biracial cohort...
Introduction: Proton pump inhibitors (PPIs) are used by an estimated 29 million Americans. PPIs increase the levels of asymmetrical dimethylarginine, a known risk factor for cardiovascular disease (CVD). Data from select population patients with CVD suggest that PPI use is associated increased stroke, heart failure, and coronary disease. The impact on incident largely unknown in general population. Hypothesis: We hypothesized users have higher total CVD, disease, failure compared to...