A5058671980- COVID-19 epidemiological studies
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 Pandemic Impacts
- COVID-19 and healthcare impacts
- Breast Cancer Treatment Studies
- Data-Driven Disease Surveillance
- COVID-19 Digital Contact Tracing
- Gastric Cancer Management and Outcomes
- Cancer Risks and Factors
- COVID-19 impact on air quality
- Health disparities and outcomes
- Diverticular Disease and Complications
- Long-Term Effects of COVID-19
- COVID-19 Impact on Reproduction
- COVID-19 diagnosis using AI
- Helicobacter pylori-related gastroenterology studies
- Poxvirus research and outbreaks
- Travel-related health issues
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- COVID-19 and Mental Health
- Influenza Virus Research Studies
National Taiwan University
2014-2024
Taichung Hospital
2021-2024
National Taiwan University of Science and Technology
2023
Taipei Medical University
2023
Taipei City Hospital
2014-2020
National Taipei University
2020
National Taipei University of Nursing and Health Science
2019
Baylor College of Medicine
2018
Low infection and case-fatality rates have been thus far observed in Taiwan. One of the reasons for this major success is better use big data analytics efficient contact tracing management surveillance those who require quarantine isolation.We present here a unique application among Taiwanese people had with more than 3000 passengers that disembarked at Keelung harbor Taiwan 1-day tour on January 31, 2020, 5 days before outbreak coronavirus disease (COVID-19) Diamond Princess cruise ship...
Colorectal cancer(CRC) is one of the most prevalent malignancies in Asia-Pacific region, and many countries this region have launched population CRC service screening. In study, screening key indicators, including FIT(fecal immunochemical test) rate (or participation rate) undergoing colonoscopy after positive FIT 2019 2020, were surveyed individual region. The impact pandemic on effectiveness was simulated given different rates assuming would persist or remain poorly controlled for a long...
Background Previously, the risk of death from breast cancer was analyzed for women participating versus those not in last screening examination before diagnosis. Consecutive attendance patterns may further refine estimates. Purpose To estimate effect participation successive mammographic examinations on mortality. Materials and Methods Participation data Swedish eligible mammography nine counties 1992 to 2016 were linked with registries regional centers diagnosis, cause, date (Uppsala...
<h3>Background & Aims</h3> In patients with positive results from a fecal immunochemical test (FIT), failure to receive timely follow-up colonoscopy may be associated higher risks of colorectal cancer (CRC) and advanced-stage CRC. We evaluated the prevalence any CRC delays in colonoscopies for FIT. <h3>Methods</h3> collected data 39,346 (age, 50–69 years) who participated Taiwanese Nationwide Screening Program 2004 through 2012 had completed more than 1 month after result Risks (stage...
Objective To measure the effects of faecal immunochemical test (FIT) for colorectal cancer (CRC) screening on overall and site-specific long-term effectiveness population-based organised service screening. Design A prospective cohort study Taiwanese nationwide biennial FIT was performed. total 5 417 699 eligible subjects were invited to attend from 2004 through 2009 followed up until 2014. We estimated adjusted relative rates (aRRs) reducing advanced-stage CRC (stage II+) death by Bayesian...
To date, 1841 cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection have been reported worldwide, with 652 deaths. We used a publically available case line list to explore the effect relevant factors, notably underlying comorbidities, on fatal outcome (MERS) up end October 2016. A Bayesian Weibull proportional hazards regression model was assess comorbidity, age, epidemic period and sex fatality rate MERS its variation across countries. The crude 32.1% (95% credibility...
<h3>Importance</h3> Different screening strategies for breast cancer are available but have not been researched in quantitative detail. <h3>Objective</h3> To assess the benefits and harms of risk-based universal mammography comparison with annual clinical examination (CBE). <h3>Design</h3> Population-based cohort study comparing incidences stage II+ disease death from across 3 strategies, adjustment a propensity score participation based on risk factors overdetection between January 1999...
Vaccine is supposed to be the most effective means prevent COVID-19 as it may not only save lives but also reduce productivity loss due resuming pre-pandemic activities. Providing results of economic evaluation for mass vaccination paramount importance all stakeholders worldwide.
Background: It has been asserted that mammography screening preferentially benefits those with less aggressive cancers, lesser or no impact on more rapidly progressing and therefore life-threatening tumors.Methods: We utilized data from the Swedish Two-County Trial, which randomized 77,080 women ages 40 to 74 invitation 55,985 for usual care. tabulated cancers by histologic grade then compared mortality specific between invited control group using Poisson regression, interest in effect 3...
Household transmission is responsible for the subsequent outbreak of community-acquired COVID-19. The aim this study was to elucidate household mode and further estimate effective basic reproductive number with without non-pharmaceutical interventions (NPIs).
The outbreak of COVID-19 on the Diamond Princess Cruise Ship provides an unprecedented opportunity to estimate its original transmissibility with basic reproductive number (R0) and effectiveness containment measures. We developed ordinary differential equation-based Susceptible-Exposed-Infected-Recovery (SEIR) model Bayesian underpinning main parameter R0 determined by transmission coefficients, incubation period, recovery rate. Markov Chain Monte Carlo (MCMC) estimation method was used...
The trajectories of all-cause deaths linked to omicron infections are rarely studied, especially in relation the efficacy booster shots. For assessing three epidemiological death trajectories, including dying from COVID-19, with and non-COVID-19 death, we offer a new COVID-19-and-death competing risk model that deals primary pathway (e.g., COVID-19) two other pathways. We applied this track trajectories: directly COVID-19 as contributing factor, indirect deaths. study used data Taiwanese...
To evaluate the time trends of colorectal cancer (CRC) affected by a Nationwide Colorectal Cancer Screening (NCCS) programme with biennial faecal immunochemical testing (FIT) and Healthcare Insurance (NHI).Data from national registries on death in Taiwan were separated into years 1984-1993, 1994-2003 2004-2013 based implementations NHI (starting 1995) NCCS 2004). The adult population was divided three age groups (young, 30-49; middle-aged, 50-69; old, 70-84 years); only middle-aged eligible...
A “Public Health Emergency of International Concern (PHEIC)” monkeypox outbreak was declared by the World Organization on 23 June 2022. More than 16,000 cases were reported in more 75 countries across six regions as July 25. The Bayesian SIR (Susceptible–Infected–Recovered) model with directed acyclic graphic method used to estimate basic/effective reproductive number (R0/Re) and assess epidemic spread globe. maximum estimated R0/Re 1.16 (1.15–1.17), 1.20 (1.20–1.20), 1.34 (1.34–1.35), 1.33...
To explain apparent differences among mammography screening services in Sweden using individual data on participation and with breast cancer-specific survival as an outcome.We analysed cancer from the Swedish Cancer Register cases nine counties diagnosed women eligible for screening. Data were available 38,278 cancers 4312 deaths. Survival to death was estimated Kaplan-Meier estimate, all each county, separately of participating not their last invitation Formal statistical comparisons made...
There is a serious concern over the variation of case fatality COVID-19 patients that reflects preparedness medical care system in response to surge pneumonia patients. We aimed quantify disease spectrum on which we are based develop key indicator probability progression from acute respiratory syndrome (ARDS) for fatal COVID-19. The retrospective cohort 12 countries have already experienced epidemic with available open data conformed cases detailed information mild (MRD), pneumonia, ARDS,...
Abstract Background: Despite age and sex differences in fecal hemoglobin (f-Hb) concentrations, most immunochemical test (FIT) screening programs use population-average cut-points for positivity. The impact of age/sex-specific threshold on FIT accuracy colonoscopy demand colorectal cancer are unknown. Methods: Using data from 723,113 participants enrolled a Taiwanese population-based with single between 2004 2009, sensitivity specificity were estimated various f-Hb thresholds This included...
Objectives To summarize debate and research in the Swedish Two-County Trial of mammographic screening on key issues trial design, endpoint evaluation, overdiagnosis, from these to infer promising directions for future. Methods A cluster-randomized controlled offer breast cancer Sweden, with a single screen control group at end phase forms setting historical review investigations analysis, interpretation results trial. Results There has been considerable commentary closure group,...
Background . To differentiate the risk of breast cancer death in a longitudinal cohort using imaging biomarkers tumor extent and biology, specifically, mammographic appearance, basal phenotype, histologic distribution, conventional attributes. Methods Using prospective study design, 498 invasive patients diagnosed between 1996 1998 were used as test to assess independent effects other predictors on death. External validation was performed with 848 2006 2010. Results Mammographic appearance...
Implementing and lifting social distancing (LSD) is an urgent global issue during the COVID-19 pandemic, particularly when travel ban lifted to revive international businesses economies. However, whether LSD can be considered subject spread of SARS-CoV-2, recovery rate, case-fatality rate. It imperative provide real-time assessment three factors guide LSD.
Background and Study Aims: The population-based colorectal cancer screening program with fecal immunochemical test (FIT) from the inaugural period to rolling-out may create a higher demand for colonoscopies, but such change has not been quantified. We intended assess in compliance rate waiting time (WT) colonoscopy associated geographic institutional variations across 2 periods. Materials Methods: Data Taiwanese nationwide were analyzed. data included total of 46,235 FIT-positive cases...
Abstract While the recent study on compassionate use of remdesivir for COVID-19 patients has shown a 68% clinical improvement 7 it is one-arm that renders evaluation efficacy in reducing death and length stay hospitalization intractable due to lacking control group. We came up with two-arm controlled design simulate treated untreated (control group) group by applying two respective transition models empirical data dynamics disease severity (Figure 2 original article ) are classified into...
Efficient evaluation with an early surrogate endpoint, taking into account the process of disease evolution, may not only clarify inconsistent or underpowered results but also provide a new insight exploration antiviral therapy for treating COVID-19 patients. We assessed dynamics spectrum, commencing from low-risk (no low oxygen supplement), medium-risk (non-invasive ventilator high and high-risk (extracorporeal membrane oxygenation invasive ventilator) risk state on enrollment, then...
Elucidating whether and how long-term survival of breast cancer is mainly due to cure after early detection effective treatment therapy or overdiagnosis resulting from the widespread use mammography provides a new insight into role plays in screening, surveillance, cancer. Given information on modes, impact screening was quantitatively assessed by applying zero (cured overdiagnosis)-inflated model design analysis 15-year follow-up cohort Dalarna, Sweden. The probability for non-progressive...