A5049507000- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Gastric Cancer Management and Outcomes
- Breast Cancer Treatment Studies
- Cancer Risks and Factors
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Oral Health Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Head and Neck Cancer Studies
- Genetic factors in colorectal cancer
- Oral microbiology and periodontitis research
- Mobile Health and mHealth Applications
- Hepatitis B Virus Studies
- Technology Use by Older Adults
- Diverticular Disease and Complications
- Radiomics and Machine Learning in Medical Imaging
- Breast Lesions and Carcinomas
- Hepatitis C virus research
- Cervical Cancer and HPV Research
- COVID-19 epidemiological studies
- Dental Health and Care Utilization
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Gastrointestinal disorders and treatments
Chang Gung University
2014-2024
Kaohsiung Chang Gung Memorial Hospital
2017-2024
National Chengchi University
2024
Northwestern Medicine
2024
National Taiwan University
2008-2021
Ministry of Health and Welfare
2015-2020
University of Sheffield
2020
Taipei Medical University
2016
Kainan University
2016
Tainan Municipal Hospital
2016
To estimate the long-term (29-year) effect of mammographic screening on breast cancer mortality in terms both relative and absolute effects.This study was carried out under auspices Swedish National Board Health Welfare. The board determined that, because randomization at a community level to invitation screening, informed verbal consent could be given by participants when they attended examination. A total 133 065 women aged 40-74 years residing two counties were randomized into group...
The effectiveness of fecal immunochemical testing (FIT) in reducing colorectal cancer (CRC) mortality has not yet been fully assessed a large, population-based service screening program.A prospective cohort study the follow-up approximately 5 million Taiwanese from 2004 to 2009 was conducted compare CRC for an exposed (screened) group and unexposed (unscreened) targeting community residents Taiwan who were 50 69 years old. Given clinical capacity, this nationwide program first rolled out...
Abstract Background Women and their health care providers need a reliable answer to this important question: If woman chooses participate in regular mammography screening, then how much will choice improve her chances of avoiding death from breast cancer compared with women who choose not participate? Methods To question, we used comprehensive registries for population, screening history, incidence, disease‐specific data defined population Dalarna County, Sweden. The annual incidence was...
Although mass eradication of Helicobacter pylori has been proposed as a means to eliminate gastric cancer, its long-term effects remain unclear.Mass H. infection was launched in 2004 and continued until 2018 for high-risk Taiwanese population aged 30 years or older dwelling on Matsu Islands with prevalent infection. Test positives the 13C-urea breath test underwent therapy. We evaluated effectiveness reducing two main outcomes, incidence mortality rates end 2016 2018, respectively.After six...
Background Previously, the risk of death from breast cancer was analyzed for women participating versus those not in last screening examination before diagnosis. Consecutive attendance patterns may further refine estimates. Purpose To estimate effect participation successive mammographic examinations on mortality. Materials and Methods Participation data Swedish eligible mammography nine counties 1992 to 2016 were linked with registries regional centers diagnosis, cause, date (Uppsala...
Abstract Background: We aimed to quantitatively assess the effect of baseline breast density on incidence, stage, and mortality, also natural course disease, considering sensitivity mammography clarify its causal or masking effect. Methods: In total, 15,658 women ages 45 59 years from Kopparberg randomized controlled trial in Sweden were prospectively followed 1977 until 2004 ascertain cancer incidence death. Dense tissue collected at beginning study was defined as pattern IV V by Tabár...
It is desirable to have a strategy for evaluation of breast cancer service screening programs years before the long-term mortality data are available. Since successful mammography has significant impact on two components TNM (tumor size, node status, presence or absence distant metastases) classification system, tumor size and we investigated effect randomized trials incidence advanced stage disease subsequent death rate. In that achieved 20% greater reduction in disease, there was an...
Background & AimsWe investigated whether 2 quantitative fecal immunochemical tests (FITs) with the same cutoff concentration of hemoglobin perform equivalently in identifying patients colorectal cancer (CRC).MethodsA total 956,005 Taiwanese subjects, 50 to 69 years old, participated a nationwide CRC screening program compare results from FITs; 78% were tested using OC-Sensor (n = 747,076; Eiken Chemical Co, Tokyo, Japan) and 22% HM-Jack 208,929; Kyowa Medex Co Ltd, Japan), 2004 through 2009....
<h3>Background & Aims</h3> In patients with positive results from a fecal immunochemical test (FIT), failure to receive timely follow-up colonoscopy may be associated higher risks of colorectal cancer (CRC) and advanced-stage CRC. We evaluated the prevalence any CRC delays in colonoscopies for FIT. <h3>Methods</h3> collected data 39,346 (age, 50–69 years) who participated Taiwanese Nationwide Screening Program 2004 through 2012 had completed more than 1 month after result Risks (stage...
Objective To measure the effects of faecal immunochemical test (FIT) for colorectal cancer (CRC) screening on overall and site-specific long-term effectiveness population-based organised service screening. Design A prospective cohort study Taiwanese nationwide biennial FIT was performed. total 5 417 699 eligible subjects were invited to attend from 2004 through 2009 followed up until 2014. We estimated adjusted relative rates (aRRs) reducing advanced-stage CRC (stage II+) death by Bayesian...
<h3>Importance</h3> Different screening strategies for breast cancer are available but have not been researched in quantitative detail. <h3>Objective</h3> To assess the benefits and harms of risk-based universal mammography comparison with annual clinical examination (CBE). <h3>Design</h3> Population-based cohort study comparing incidences stage II+ disease death from across 3 strategies, adjustment a propensity score participation based on risk factors overdetection between January 1999...
<h3>Objectives</h3> Interval colorectal cancer (CRC) after colonoscopy may affect effectiveness and cost-effectiveness of screening programmes. We aimed to investigate whether how faecal haemoglobin concentration (FHbC) immunochemical testing (FIT) affected the risk prediction interval (IC) caused by inadequate quality in a FIT-based population programme. <h3>Design</h3> From 2004 2009, 29 969 subjects underwent complete positive FIT Taiwanese Nationwide CRC Screening Program. The IC rate...
To assess the effect of an incremental increase in faecal haemoglobin (f-Hb) concentration on colorectal cancer (CRC) mortality and all-cause death.We conducted observational study cohorts over time based two population-based CRC screening programmes.Two cities Taiwan.1233 individuals with (217 prevalent cases 1016 incident cases) 2640 adenoma (1246 1394 found 59 767 125 976 apparently healthy individuals, aged 40 years above, who had been invited to participate since 2001 2003,...
To what extent the risk for colorectal cancer (CRC) death among noncompliers of colonoscopy is elevated following positive fecal immunological testing and whether varies with hemoglobin concentration (f-Hb) location CRC have not been researched.We used data on 59 389 individuals (4.0%) 1 489 937 Taiwanese screenees age 50 to 69 years f-Hb 20 μg or more per gram feces from 2004 2009. They were classified into 41 995 who received 10 778 no confirmatory examination; latter was categorized three...
Public access defibrillation (PAD) programs have been implemented globally over the past decade. Although PAD can substantially increase survival of cardiac arrest, use remains low. This study aimed to evaluate whether drawing upon successful experiences dispatcher-assisted cardiopulmonary resuscitation would in programs.
We investigated the association between type 2 diabetes mellitus (T2DM) and periodontal disease (PD) in context of current aetiology model.In total, 14,747 community residents aged 35-44 years were invited to a community-based PD survey 2003 2006 using index. Significant factors modifying T2DM ascertained. further assessed risk for PD, within strata significant effect modifiers, after controlling other putative factors.The prevalence rate was 10% higher subjects with than those without....
Asian women have a younger age at onset of breast cancer and lower body mass index (BMI) than Western women. The link between obesity risk in is still elusive. We aimed to investigate the effect BMI on incident Taiwanese A total 1 393 985 who had been cancer-free before recruitment attended nation-wide cancer-screening program 1999 2009 were enrolled using prospective cohort study. Obesity other relevant variables (such as menopause status biochemical markers) collected through in-person...
Vascular access (VA) is the cornerstone for carrying out hemodialysis, yet it may bring in complications and leads to hemodialysis quality decline. This study aimed explore impact of vascular types, including arteriovenous shunts central venous catheter on all-cause mortality after adjustment other risk factors. Total 738 ESRD patients aged over 40 year old receiving regular therapies were recruited between January 2001 December 2010 from a single center northern Taiwan. We ascertained...
Background Advances in voice technology have raised new possibilities for apps related to daily health maintenance. However, the usability of such technologies older users remains unclear and requires further investigation. Objective We designed evaluated two innovative mobile voice-added food intake reporting, namely voice-only reporting (VOR) voice-button (VBR). Each app features a unique interactive procedure intake. With VOR, verbally report main contents each dish, while VBR provides...
Early detection of oral premalignant lesions (OPMLs) by visual inspection with toluidine blue has not been addressed. We conducted a community-based randomized controlled trial to assess whether using as an adjunctive tool for screening had higher rate OPMLs and could further reduce the incidence cancer. In 2000, in Keelung, we randomly assigned total 7975 individuals, aged 15 years or older high-risk habits, either toluidine-blue-screened (TBS) group group. Results showed 5% more 79%...
Combined information on single nucleotide polymorphisms and prostate specific antigen offers opportunities to improve the performance of screening by risk stratification. We aimed predict cancer based together with polymorphism information.We performed a prospective study 20,575 men testing 4,967 polygenic score for 66 from Finnish population trial 5,269 samples 7 DNA study. A Bayesian predictive model was built estimate sequentially combining genetic compared alone in subjects limited those...