A5087450728- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gastroesophageal reflux and treatments
- Meningioma and schwannoma management
- Eosinophilic Esophagitis
- Lung Cancer Treatments and Mutations
- Esophageal and GI Pathology
- Neuroblastoma Research and Treatments
- Obesity, Physical Activity, Diet
- Cardiovascular Health and Risk Factors
- Cardiovascular Effects of Exercise
- Health Systems, Economic Evaluations, Quality of Life
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Breast Implant and Reconstruction
- Neurofibromatosis and Schwannoma Cases
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- Microscopic Colitis
- COVID-19 Clinical Research Studies
- Liver Diseases and Immunity
- MicroRNA in disease regulation
- Venous Thromboembolism Diagnosis and Management
- Anesthesia and Pain Management
University Hospitals of Cleveland
2019-2024
University Health System
2020-2024
Center for Clinical Research (United States)
2022-2024
Case Western Reserve University
2019-2024
University School
2019-2024
University of Pennsylvania
2024
Bridge University
2024
Central Brain Tumor Registry of the United States
2019-2022
Richmond University Medical Center
2021
Case Comprehensive Cancer Center
2021
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with Centers for Disease Control and Prevention National Cancer Institute, is largest population-based registry focused exclusively on primary brain other central nervous system (CNS) tumors (US) represents entire US population. This report contains most up-to-date data available supersedes all previous reports terms completeness accuracy. All rates are age-adjusted using 2000 standard population presented per...
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with Centers for Disease Control (CDC) and National Cancer Institute (NCI), is largest population-based registry focused exclusively on primary brain other central nervous system (CNS) tumors (US) represents entire US population. This report contains most up-to-date data (malignant non-malignant) supersedes all previous CBTRUS reports terms completeness accuracy. All rates (incidence mortality) are age-adjusted...
Abstract Brain and other central nervous system (CNS) tumors are among the most fatal cancers account for substantial morbidity mortality in United States. Population‐based data from Central Tumor Registry of States (a combined set National Program Cancer Registries [NPCR] Surveillance, Epidemiology, End Results [SEER] registries), NPCR, Vital Statistics System SEER program were analyzed to assess contemporary burden malignant nonmalignant brain CNS (hereafter brain) by histology, anatomic...
Introduction Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may trigger autoimmune disease (AD) through initial innate immune activation with subsequent aberrations in adaptive cells leading to AD. While there are multiple reports of incident AD diagnosed after COVID-19, the risk context key circulating strains is unknown. Methods TriNetX, a global, federated, health research network providing access electronic medical records across 74 healthcare organizations, was utilized...
Background Breast implant illness (BII) after aesthetic breast augmentation remains a poorly defined syndrome encompassing wide spectrum of symptoms. While previously published series have observed overall symptomatic improvement removal, 1–3 there is lack studies evaluating changes in specific symptoms over time. The purpose this study was to gain an understanding associated with BII, and evaluate how these change removal implants total capsulectomy (explantation). We hypothesized that...
Background People with HIV (PWH) are at higher risk of complications from acute COVID-19, but their subsequent post-acute sequelae SARS-CoV2 (PASC) remains unclear. Although vaccination is protective PASC among survivors in the general population, its effectiveness PWH has not been explored. Methods We used TriNetX health research database to identify patients and without aged ≥18 years confirmed SARS-CoV-2 between January 1, 2020 July 20, 2023. employed 1:1 propensity score matching balance...
Abstract Background Gliomas are the most common type of malignant brain and other CNS tumors, accounting for 80.8% primary tumors. They cause significant morbidity mortality. This study investigates intersection between age sex to better understand variation incidence survival glioma in United States. Methods Incidence data from 2000 2017 were obtained CBTRUS, which obtains NPCR SEER, CDC’s NPCR. Age-adjusted rate ratios (IRR) per 100 000 generated compare male-to-female by group. Cox...
Abstract Background Limited population-based data exist for the brainstem gliomas children ages ≤19 years, which includes high-grade aggressively growing tumors such as diffuse intrinsic pontine glioma (DIPG). We examined overall incidence and survival patterns in with (HGG) by age, sex, race ethnicity. Methods used from Central Brain Tumor Registry of United States (CBTRUS), obtained through use agreements Centers Disease Control (CDC) National Cancer Institute (NCI) 2000 to 2017, CDCs...
The NIH Revitalization Act, implemented 29 years ago, set to improve the representation of women and minorities in clinical trials. In this study, we investigate progress made all phase therapeutic trials for neuroepithelial CNS tumors stratified by demographic-specific age-adjusted disease incidence mortality. Additionally, identify workforce characteristics associated with meeting established accrual benchmarks.Registry study published World Health Organization defined between January 2000...
Goals: The purpose of our study was to evaluate trends hospitalization, acute kidney injury (AKI) and mortality in cirrhotic patients with spontaneous bacterial peritonitis (SBP). Background: SBP is a frequent infection leading increased morbidity mortality. Materials Methods: A total 4,840,643 hospitalized cirrhosis from 2005 2014 were identified using the Nationwide Inpatient Sample database, which 115,359 (2.4%) had SBP. We examined annual used multivariable mixed-effects logistic...
There are over 100 histologically distinct types of primary malignant and nonmalignant brain other central nervous system (CNS) tumors. Our study presents recent trends in the incidence these tumors using an updated histology recode that incorporates major diagnostic categories listed 2016 World Health Organization Classification Tumours CNS.We used data from SEER-21 registries for patients all ages diagnosed 2000-2017. We calculated age-adjusted rates fitted a joinpoint regression to...
Understanding sex-based differences in patients with glioblastoma is necessary for accurate personalized treatment planning to improve patient outcomes. Our purpose was investigate sex-specific molecular, clinical, and radiologic tumor parameters, as well survival outcomes glioblastoma, isocitrate dehydrogenase-1 wild-type (IDH1-WT), grade 4. Retrospective data of 1832 IDH1-WT comprehensive information on parameters acquired from the Radiomics Signatures Precision Oncology Glioblastoma...
Gliomas are the most common type of primary malignant brain tumor in adults, representing one third all and central nervous system (CNS) tumors 80% diagnosed Western world. Epidemiological data indicate that overall incidence mortality cancer is higher males, while females have a better prognosis. The goal this study to determine whether there sex differences time treat clinical outcomes patients with glioma.Glioblastoma (GB) Lower Grade Glioma (LGG) were defined per Central Brain Tumor...
The effect of emergency medicine (EM) residents on the clinical efficiency attending physicians is controversial. authors hypothesized that implementing a new EM residency program would result in an increase relative value units (RVUs) generated per hour by and decrease staffing requirements.This was retrospective observational analysis department before, during, after establishment program. We analyzed change RVUs billed, patients seen, hours worked physicians, midlevel providers (MLPs),...
To evaluate the 1- and 2-year patency reintervention rates with Zilver PTX drug-eluting stent (DES) in long complex femoropopliteal disease.A retrospective review was conducted of 89 consecutive patients (mean age 68.7±9.8 years; 86 men) occlusive disease (Rutherford category 2-6) treated between December 2012 2013. Mean lesion length for entire cohort 24.2±11.3 cm (median 24.0, range 4-48). The patient population dichotomized into a short (≤20 cm) group (n=41; mean 13.3±5.6 full DES jacket...
An elevation of serum inflammatory biomarkers in achalasia patients compared with controls recently was demonstrated. It has not been determined whether the cytokines is unique to or occurs other diseases involving esophagus. The primary aim our study compare differences plasma immunological profiles (TNF- α receptor, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23) achalasia, eosinophilic esophagitis (EoE), gastroesophageal reflux disease (GERD). A secondary this classify these same cytokine...
Vestibular schwannomas (VS) are nonmalignant tumors of the eighth cranial nerve and most common sheath tumor. This study provides comprehensive current analysis VS epidemiology in United States.Incidence data were obtained from Central Brain Tumor Registry States, 2004 to 2016 for VS. Age-adjusted incidence rates (AAIRs), rate ratios (AAIRRs), prevalence (AAPRs) per 100 000 analyzed by age, sex, race ethnicity, laterality. Additional analyses performed assess differences treatment,...
The Central Brain Tumor Registry of the United States (CBTRUS) uses a histology grouping model based on World Health Organization (WHO) classifications to group records for clinically relevant statistical reporting. Newly identified genetic markers more accurately stratify patients than alone and were incorporated into 2016 update WHO Classification. CBTRUS consulting neuropathologists reviewed aligned groupings with update. "Obsolete" (terms not currently in use) nomenclature along their...