A5011621010- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Protease and Inhibitor Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Allergic Rhinitis and Sensitization
- DNA Repair Mechanisms
- Oral microbiology and periodontitis research
- Pleural and Pulmonary Diseases
- Peptidase Inhibition and Analysis
- Pneumothorax, Barotrauma, Emphysema
- Epigenetics and DNA Methylation
- Dermatology and Skin Diseases
- Inflammasome and immune disorders
- Obstructive Sleep Apnea Research
- Pneumonia and Respiratory Infections
- Occupational and environmental lung diseases
- Systemic Lupus Erythematosus Research
- Urticaria and Related Conditions
- RNA modifications and cancer
- Medical Imaging and Pathology Studies
- Gastroesophageal reflux and treatments
- Respiratory Support and Mechanisms
- Esophageal and GI Pathology
- Cytokine Signaling Pathways and Interactions
- Pneumocystis jirovecii pneumonia detection and treatment
First Affiliated Hospital Zhejiang University
2025
China Medical University Hospital
2015-2024
China Medical University
2015-2024
National Yang Ming Chiao Tung University
2015-2024
Chu Shang Show Chwan Hospital
2014-2024
National Defense Medical Center
2018
Asia University
2018
China Medical University
2015-2016
Bridge University
2016
Pulmonary and Critical Care Associates
2015
Background: Treatment options for patients with refractory inflammatory bowel disease (IBD) or concomitant IBD and extraintestinal manifestations (EIM) are often limited. Objective: This study aimed to examine the efficacy safety of combining biologics small molecules in IBD, active EIM, immune-mediated (IMID). Design: was a retrospective multicenter study. Methods: We retrospectively collected demographics characteristics from 47 who received dual-targeted therapy 3 hospitals January 2022...
Background There are several publications reported that obstructive sleep apnea (OSA) was associated with asthma. However, large-scaled, population-based cohort study has been limited. We aimed to examine the risk of OSA among adult patients asthma in an Asian population. Methods conducted a retrospective using data from National Health Insurance (NHI) Taiwan. The included 38,840 newly diagnosed between 2000 and 2010. date diagnosis defined as index date. Each patient randomly matched four...
Several studies have reported an association between chronic obstructive pulmonary disease (COPD) and periodontal diseases. However, a large-scale population-based cohort study was previously absent from the literature. Therefore, we evaluated risk of diseases in patients with COPD nationwide population. From National Health Insurance claims data Taiwan, identified 22,332 who were newly diagnosed during 2000 to 2010. For each case, two individuals without randomly selected frequency matched...
Background: The role of autoimmune pathology in development and progression chronic obstructive pulmonary disease (COPD) is becoming increasingly popular.Our aim was to assess the association between patients with rheumatoid arthritis (RA) subsequent COPD risk a nationwide population.Method: We conducted retrospective cohort study using data from National Health Insurance system Taiwan.The RA included who were newly diagnosed recruited 1998 2008.Each patient randomly frequency-matched for...
The association between type 1 diabetes mellitus (T1DM) and asthma remains controversial has led to new interest in these 2 disorders. purpose of this study was examine the associations among young people with T1DM offer a clinical demonstration balance Th1 Th2 responses.We conducted retrospective cohort by using data from National Health Insurance (NHI) system Taiwan. consisted 3545 cases 14,180 controls established during 1998 2011 period. Of patients, 55.1% were girls 26.5% age group <8...
Background: Several studies discussed the relations between asthma and rheumatoid arthritis (RA) but results were controversial. These either questionnaire based or with small study populations. We aimed to examine risk of among RA patients in a nationwide population. Methods: conducted cohort using data from National Health Insurance system Taiwan. The included 27 602 who newly diagnosed recruited 1998 2008. Each patient was randomly frequency-matched three people without on age group, sex...
Treatment of periodontal diseases has been associated with benefit outcomes for patients chronic obstructive pulmonary disease (COPD). However, no population-based cohort study conducted. We evaluated this relationship by retrospective using a large population data. Using the National Health Insurance claims data Taiwan, we identified 5562 COPD who had received treatment as group. The comparison group was selected at 1:1 ratio matched propensity score estimated age, sex, date diagnosis and...
Lung cancer screening using low-dose computed tomography (CT) has been reported to reduce lung cancer-specific mortality for smokers at high risk. However, despite different characteristics of in Asia, there are few data concerning this specific population screening. We aim analyze the performance with CT concurrent chest radiography Taiwan, reference international experience.During 1-year period from January 2012 December 2012, we conducted a retrospective, single-center population-based...
Background There is a demonstrated association between asthma and irritable bowel syndrome (IBS). In this study, we examined the bidirectional IBS using nationwide database. Methods We conducted two retrospective cohort studies data obtained from National Health Insurance of Taiwan. Study 1 included 29,648 patients newly diagnosed 2000 2010. 2 29,875 patient For each four subjects without were selected, respectively, frequency-matched by sex, age, diagnosis date. All cohorts followed up...
Objective Sleep disorders are prevalent medical in patients with rheumatoid arthritis (RA). However, whether RA at an increased risk of developing obstructive sleep apnoea (OSA) is unclear. Design Using population-based retrospective cohort study to examine the OSA RA. Setting We used claims data National Health Insurance Research Database (NHIRD) Taiwan. Participants identified a 33 418 newly diagnosed 2000–2010 and randomly selected non-RA comparison individuals frequency matched by sex,...
Numerous studies have reported the over-expression of radiation-sensitive protein 51 (RAD51) in various types cancer. However, role RAD51 genotypes lung cancer remains largely unknown. This study aimed to assess impact common variant rs1801320 (G-135C) on risk Taiwan.
Background: Studies have reported an association between asthma and oral diseases, including periodontal diseases. The aim of this retrospective study is to investigate risk diseases for patients with asthma. Methods: Using the claims data National Health Insurance Taiwan without a history 19,206 asthmatic patients, who were newly diagnosed from 2000 through 2010, identified. For each case, four comparison individuals disease randomly selected general population frequency matched...
Background: Clinical and immunological studies have consistently shown a possible link between atopy idiopathic nephrotic syndrome (INS). However, whether allergic diseases occur after INS develops is unknown.Methods: From Taiwan’s National Health Insurance database, 1340 children with newly diagnosed 5360 non-INS matched controls were identified in 2000–2007. By the end of 2008, incidences hazard ratios four (allergic conjunctivitis, rhinitis, atopic dermatitis, asthma) calculated.Results:...
ABSTRACT Objectives: The aim of the study was to systemically investigate risk subsequent irritable bowel syndrome (IBS) in children with antecedent allergic diseases a population‐based case‐control Taiwan. Methods: We evaluated 11,242 (age range: 7–18 years) IBS and 44,968 age‐ sex‐matched control subjects who had been examined between 2000 2008. odds ratios were calculated for diseases, including conjunctivitis, rhinitis, asthma, atopic dermatitis, urticaria, food allergy. Results:...
We aimed to compare the surgical outcomes between hysterectomy by transvaginal natural orifice transluminal endoscopic surgery (vNOTES) and laparoscopic total (LTH).This study is a retrospective chart analysis. From January 1, 2015, December 31, 2017, of 183 patients reproductive age with an indication for due non-prolapsed benign uterine diseases were enrolled. After exclusion, 20 included in vNOTES group, 66 LTH group. Various post-operative such as operative time, blood loss, uterus...
There is increasing evidence that autoimmune disease associated with development of chronic obstructive pulmonary (COPD). We aim to assess the relationship between systemic lupus erythematosus (SLE) and COPD risk in a nationwide population.We conducted retrospective cohort study using catastrophic illness registry Taiwan National Health Insurance Research Database (NHIRD). identified 10,623 patients SLE newly diagnosed 2000 2010. Each patient was randomly frequency-matched four people...