A5071346131- Trypanosoma species research and implications
- Dietary Effects on Health
- Gut microbiota and health
- Dermatological diseases and infestations
- Food Safety and Hygiene
- Viral Infections and Immunology Research
- Cardiomyopathy and Myosin Studies
- Gastrointestinal motility and disorders
- Listeria monocytogenes in Food Safety
- Skin Protection and Aging
- Advancements in Transdermal Drug Delivery
- Periodontal Regeneration and Treatments
- Essential Oils and Antimicrobial Activity
- Tendon Structure and Treatment
- Rabies epidemiology and control
- Parasitic Infections and Diagnostics
- Research on Leishmaniasis Studies
- Bartonella species infections research
- Retinoids in leukemia and cellular processes
- Wound Healing and Treatments
- Global Maternal and Child Health
- Radiation Effects and Dosimetry
- RNA regulation and disease
- Nuclear Receptors and Signaling
- Hearing, Cochlea, Tinnitus, Genetics
Universidade de Brasília
2014-2025
Fundação Oswaldo Cruz
2013
Schistosomiasis has expanded to the coast of Pernambuco State, Brazil, where there are frequent reports Biomphalaria glabrata snails and human cases disease. This study analyzes factors related schistosomiasis transmission risk in Porto de Galinhas. A one-year malacological survey was conducted identify biological, abiotic, environmental host snail breeding sites. Data analysis used Excel 2010, GTM Pro, ArcGis 10. total 11,012 B. were captured 36 sites, 11 foci identified. negative...
Introduction Age-related hearing loss (ARHL) is a consequence of aging the auditory system. The best known mechanism cell death in ARHL apoptosis due to increased production reactive oxygen species. In this context, it hypothesized that melatonin, owing its high antioxidant potential and action mitochondria, helps prevent or delay outer hair dysfunction (HCD). Aims To evaluate effect melatonin on prevention HCD process susceptible murine C57BL/6J model. Method animals were divided into two...
Abstract Gut dysbiosis is linked to metabolic and neurodegenerative diseases comprises a plausible link between high‐fat diet (HFD) brain dysfunction. Here we show that gut microbiota modulation by either antibiotic treatment for 5 weeks or brief 3‐day fecal transplantation (FMT) regimen from low‐fat (control) diet‐fed mice decreased weight gain, adipose tissue hypertrophy, glucose intolerance induced HFD in C57BL/6 male mice. Notably, FMT completely reversed impaired recognition memory HFD,...
Background Infection with the protozoan Trypanosoma cruzi manifests in mammals as Chagas heart disease. The treatment available for chagasic cardiomyopathy is unsatisfactory. Methods/Principal Findings To study disease pathology and its inhibition, we employed a syngeneic chicken model refractory to T. which chickens hatched from inoculated eggs retained parasite kDNA (1.4 kb) minicircles. Southern blotting EcoRI genomic DNA digests revealed main 18 20 kb bands by hybridization radiolabeled...
The human skin aging process is a complex mechanism that can be induced both by intrinsic and extrinsic factors. Observations include decrease in the biosynthetic proliferative capacity of cells, increased expression matrix metalloproteinases, reduction collagen type I expression, progressive disappearance elastic tissue papillary dermis. L-arginine, substrate nitric oxide synthesis, involved angiogenesis cell proliferation, as well an indirect precursor synthesis via proline pathway. aim...
Previous studies have discussed the low prevalence of psoriasis among indigenous peoples South America. The state Roraima, Brazil, where present study was performed, is crossed by equator line. It likely that key factors for absence in this population include genetic factors, a lack environmental triggers and high sun exposure.
Trypanosoma cruzi circulates in sylvatic habitats, mainly through blood-feeding triatomines, although other routes also contribute to its dispersion. Sexual transmission of T. is an understudied topic, especially among wild mammals. Because the difficulties inherent field work, experimentally infected mice are frequently used evaluate cruzi.This study aimed sexual acutely mice.Male and female acute phase Chagas disease were mated with naïve partners. Then, parasitological tests,...
Listeria monocytogenes é um patógeno relevante veiculado por alimentos. Sua identificação precisa importante para a correta determinação do risco associado à ingestão alimento. O objetivo deste trabalho foi verificar ocorrência das espécies de spp. em amostras salsichas tipo hot dog e carne moída bovina, comercializadas granel no Distrito Federal. Foram analisadas 162 amostras, sendo 127 35 bovina. isolamento gênero foram feitos metodologia convencional distinção verificada kit bioquímico...
Background: Tungiasis is a disease associated with extreme poverty. We aimed to evaluate the prevalence of tungiasis in six different settlements Sanumás indigenous community remote area Auaris region, Yanomami territory, Brazil. Methods: conducted an observational study detect clinical and epidemiological factors using cross-sectional strategy multivariate logistic regression. Soil analysis was performed by visual microscopic methods. Results: examined 555 persons, 45 whom had active...
Chondrocytes obtained from stifle joint of New Zealand White rabbits were cultivated. Half cells maintained in culture for later implantation and the others frozen during six months to evaluate viability. A circular osteochondral defect was created right other twenty seven rabbits. The control group (CG) received no treatment. thawed (TH) fresh (FH) heterologous groups received, respectively, an implant cultivated or chondrocytes associated with platelet rich plasma (PRP). CG showed greatest...
Background: The success of tungiasis treatment is highly dependent on adequate environmental control. Methods: This a real-world observational cohort study designed to monitor the effectiveness topical dimethicone together with One Health approach for control in Sanumás communities, Amazon rainforest, Brazil. We followed up 562 indigenous people and 81 domestic dogs 1.5 years 3-month interval. A new molecular method large-scale soil evaluation was also tested. independently conducted by...