A5002654577- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Polyomavirus and related diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Parvovirus B19 Infection Studies
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Antenna Design and Analysis
- Lipoproteins and Cardiovascular Health
- Clinical Nutrition and Gastroenterology
- Long-Term Effects of COVID-19
- Acute Ischemic Stroke Management
- Poisoning and overdose treatments
- Urticaria and Related Conditions
- Pharmaceutical and Antibiotic Environmental Impacts
- Mitochondrial Function and Pathology
- Case Reports on Hematomas
- Inflammatory mediators and NSAID effects
- Platelet Disorders and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular Issues in Pregnancy
University of Maryland, Baltimore
2018-2024
University of Maryland Medical Center
2018-2024
Thrombocytopenia is common during extracorporeal membrane oxygenation (ECMO), and platelets are sometimes transfused to meet arbitrary goals. We performed a retrospective cohort study of veno-arterial (VA) ECMO patients from single academic medical center explored the relationship between platelet transfusion in-hospital mortality using multivariable logistic regression. One hundred eighty-eight VA were included in study. Ninety-one (48.4%) ECMO. Patients who received had more coronary...
Sensitization remains a barrier to heart transplantation (HT). Perioperative desensitization strategies have been described; however, paucity of evidence exists demonstrate efficacy and safety in HT.This single-center, retrospective study consisted adults who received an HT. was initiated if virtual crossmatch or flow-cytometry positive. Therapy plasmapheresis, intravenous immunoglobulin, rabbit antithymocyte globulin. Historical controls standard immunosuppression induction. The primary...
Advanced liver disease or cirrhosis is associated with an increased risk of infections; however, the impact high pretransplant model for end-stage (MELD) score on cytomegalovirus (CMV) viremia after transplantation unknown.This single-center, retrospective, cohort study evaluated CMV high-risk (CMV immunoglobulin G D+/R-) transplant recipients who received valganciclovir prophylaxis 3 months between 2009 and 2019. Patients were stratified by MELD <35 (low MELD) ≥35 (high MELD). The primary...
Introduction Hypoalbuminemia is predictive of mortality in critically ill patients, especially those with cardiac etiologies illness. The objective this study was to determine the association albumin level pre-cannulation for veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) and important clinical hospital outcomes. Methods This a retrospective, observational cohort levels patients cardiogenic shock requiring V-A ECMO between December 2015 August 2021 single, high-volume center....
Introduction: Pregnancy in patients with advanced heart failure requiring left ventricular assist device (LVAD) support is risky and discouraged, though there are cases of successful deliveries. Hypothesis: A 29-year-old G3P2002 female history embolic cerebrovascular accident, postpartum hemorrhage, peripartum cardiomyopathy status-post HeartMate 3 (HM3) LVAD, became pregnant after intrauterine dislodgement. She elected to continue the pregnancy against advice maternal-fetal medicine (MFM)....
It remains unclear whether patients who will not accept allogeneic blood transfusion can be managed successfully with veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO). The objective of our study was to determine what percentage V-A ECMO were without transfusion.This a retrospective, observational cohort cardiogenic shock requiring between January 2016 and 2019. primary outcome avoidance any transfusion.Of the 206 included, 23 (11.2%) transfusion. Fourteen (60.9%) avoided during...
Approximately 795 000 people in the United States experience stroke annually, with 610 initial and 185 recurrent events.1 The majority of these events (87%) are ischemic nature.1 Stroke ranks fifth among all causes death States, although rates mortality due to have decreased overall by 2.3% between 2005 2015.1 Given aging population it is likely that incidence will continue rise. The management patients acute (AIS) continues evolve, recent publication several trials evaluating...
We previously reported low rates of pump thrombosis and hemorrhagic stroke, but increased bleeding, under our original antithrombosis protocol (P1) in HeartWare recipients. designed implemented a revised (P2) to reduce complexity bleeding. Thrombelastography PFA-100 guide antiplatelet titration. Goals for P2 were altered decrease use anticoagulation intensity. compared the incidence gastrointestinal bleeding (GIB), embolic (eCVA) (hCVA) (PT), total (GIB+hCVA), (eCVA+PT), events between P1...
Background: Patients with severe COVID-19 related respiratory failure may require veno-venous extracorporeal membrane oxygenation (VV ECMO). After decannulation, patients on VV ECMO have historically had high percentages of cannula-associated deep vein thrombosis (CaDVT). Due to their hypercoagulable state and prolonged course ECMO, we hypothesized that would experience a higher rate CaDVT when compared non-COVID-19 counterparts. We also described the association between location size...