A5025254158- Bat Biology and Ecology Studies
- Viral Infections and Vectors
- Zoonotic diseases and public health
- Yersinia bacterium, plague, ectoparasites research
- Species Distribution and Climate Change
- Primate Behavior and Ecology
- Animal Ecology and Behavior Studies
- Evolution and Paleontology Studies
- Amphibian and Reptile Biology
- Physiological and biochemical adaptations
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Effects of Environmental Stressors on Livestock
- Viral Infections and Outbreaks Research
- Wildlife Ecology and Conservation
- Animal Behavior and Welfare Studies
- Environmental and Biological Research in Conflict Zones
- SARS-CoV-2 and COVID-19 Research
- Vector-borne infectious diseases
- Rabies epidemiology and control
- Avian ecology and behavior
- Animal Behavior and Reproduction
- Parasite Biology and Host Interactions
- Vibrio bacteria research studies
- Child and Animal Learning Development
Bucknell University
2015-2024
Arizona State University
2020-2022
Meise Botanic Garden
2020-2022
EcoHealth Alliance
2021-2022
Research Institute for Nature and Forest
2022
University of Turin
2022
Ronin Institute
2020-2022
University of California, Santa Barbara
2022
Stellenbosch University
2022
American Museum of Natural History
2020-2022
We review developments in the study of stress free-ranging mammals and summarize physiological behavioral components response. Both sympathetic nervous system response regulation reactivity hypothalamic–pituitary–adrenal (HPA) axis are discussed. In particular, we describe how activity HPA at baseline levels follows circadian circannual rhythms ways that allow animals to respond predictable environmental changes, focusing largely on endpoint this axis, glucocorticoid hormones cortisol...
White-nose syndrome (WNS), an emerging infectious disease that has killed over 5.5 million hibernating bats, is named for the causative agent, a white fungus (Geomyces destructans (Gd)) invades skin of torpid bats. During hibernation, arousals to warm (euthermic) body temperatures are normal but deplete fat stores. Temperature-sensitive dataloggers were attached backs 504 free-ranging little brown bats (Myotis lucifugus) in hibernacula located throughout northeastern USA. Dataloggers...
Tissue regenerative potential displays striking divergence across phylogeny and ontogeny, but the underlying mechanisms remain enigmatic. Loss of mammalian cardiac correlates with cardiomyocyte cell-cycle arrest polyploidization as well development postnatal endothermy. We reveal that diploid abundance 41 species conforms to Kleiber's law-the ¾-power law scaling metabolism bodyweight-and inversely standard metabolic rate, body temperature, serum thyroxine level. Inactivation thyroid hormone...
The emerging wildlife disease white-nose syndrome is causing widespread mortality in hibernating North American bats. White-nose occurs when the fungus Geomyces destructans infects living skin of bats during hibernation, but links between infection and are underexplored. We analyzed blood from compared electrolyte levels to wing damage caused by fungus. Sodium chloride tended decrease as increased severity. Depletion these electrolytes suggests that infected may become hypotonically...
White-nose syndrome (WNS) in North American bats is caused by an invasive cutaneous infection the psychrophilic fungus Pseudogymnoascus destructans (Pd). We compared transcriptome-wide changes gene expression using RNA-Seq on wing skin tissue from hibernating little brown myotis (Myotis lucifugus) with WNS to without Pd exposure. found that significant including pathways involved inflammation, wound healing, and metabolism. Local acute inflammatory responses were initiated fungal invasion....
Definitive diagnosis of the bat disease white-nose syndrome (WNS) requires histologic analysis to identify cutaneous erosions caused by fungal pathogen Pseudogymnoascus [formerly Geomyces] destructans (Pd). Gross visual inspection does not distinguish bats with or without WNS, and no nonlethal, on-site, preliminary screening methods are available for WNS in bats. We demonstrate that long-wave ultraviolet (UV) light (wavelength 366-385 nm) elicits a distinct orange-yellow fluorescence...
In August 2012, a wildlife biologist became ill immediately following 6-wk field trip to collect bats and rodents in South Sudan Uganda. After returning the US, was admitted hospital with multiple symptoms including fever, malaise, headache, generalized myalgia arthralgia, stiffness neck, sore throat. Soon after admission, patient developed maculopapular rash oropharynx ulcerations. The remained hospitalized for 14 d. Several suspect pathogens, viral hemorrhagic fever viruses such as Ebola...
An estimated 5.7 million or more bats died in North America between 2006 and 2012 due to infection with the fungus Pseudogymnoascus destructans (Pd) that causes white-nose syndrome (WNS) during hibernation. The behavioral physiological changes associated hibernation leave vulnerable WNS, but persistence of within contaminated regions suggests survival might vary predictably among individuals relation environmental conditions. To investigate variables influencing WNS mortality, we conducted a...
Despite being heavily exploited, pangolins (Pholidota: Manidae) have been subject to limited research, resulting in a lack of reliable population estimates and standardised survey methods for the eight extant species. Camera trapping represents unique opportunity broad-scale collaborative species monitoring due its largely non-discriminatory nature, which creates considerable volumes data on relatively wide range This has potential shed light ecology rare, cryptic understudied taxa, with...
Abstract In 2012, a female wildlife biologist experienced fever, malaise, headache, generalized myalgia and arthralgia, neck stiffness, sore throat shortly after returning to the United States from 6-week field expedition South Sudan Uganda. She was hospitalized, which maculopapular rash developed became confluent. When patient discharged hospital on day 14, arthralgia had improved, oropharynx ulcerations healed, resolved without desquamation, blood counts hepatic enzyme levels were...
White-nose syndrome (WNS) has devastated bat populations in North America, with millions of bats dead. WNS is associated physiological changes hibernating bats, leading to increased arousals from hibernation and premature consumption fat reserves. However, there evidence surviving little brown myotis (Myotis lucifugus) close where the fungus was first detected nearly ten years ago.We examined patterns a population compared them before arrival at peak mortality. Despite infection...
White-nose syndrome (WNS) is a fungal disease responsible for decimating many bat populations in North America. Pseudogymnoascus destructans ( Pd ), the psychrophilic fungus WNS, prospers winter habitat of hibernating species. The immune response that elicits bats not yet fully understood; antibodies are produced to infection by , but they may be protective and indeed harmful. To understand how respond during hibernation, we studied effect inoculation on survival gene expression captive...
Hibernation, the use of prolonged torpor to depress metabolism, is employed by mammals conserve resources during extended periods extreme temperatures and/or resource limitation. Mammalian hibernators arouse euthermy periodically for reasons that are not well understood, and these arousals may facilitate immune processes. To determine whether enable host responses pathogens, we used dual RNA-Seq a paired sampling approach examine gene expression in hibernating bat, little brown myotis...