A5001541620- Neural dynamics and brain function
- Cell Image Analysis Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience and Neuropharmacology Research
- Advanced Electron Microscopy Techniques and Applications
- Axon Guidance and Neuronal Signaling
- Cellular Mechanics and Interactions
- Single-cell and spatial transcriptomics
Center for Excellence in Brain Science and Intelligence Technology
2022-2023
Chinese Academy of Sciences
2022-2023
University of Chinese Academy of Sciences
2023
The morphology and spatial distribution of axon arbors boutons are crucial for neuron presynaptic functions. However, the principles governing their whole-brain organization at single-neuron level remain unclear. We developed a machine-learning method to separate from passing axons in reconstruction fluorescence micro-optical sectioning tomography imaging data obtained 62,374 that displayed distinct morphology, patterns, scaling laws dependent on types targeted brain areas. Focusing thalamus...