A5045591391- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Advanced Neuroimaging Techniques and Applications
- Glioma Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
- Alzheimer's disease research and treatments
- Neural dynamics and brain function
- Mental Health Research Topics
- Advanced MRI Techniques and Applications
- Energetic Materials and Combustion
- Nonlinear Optical Materials Research
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- Motor Control and Adaptation
- Memory and Neural Mechanisms
- Combustion and Detonation Processes
- Neurological Disease Mechanisms and Treatments
- Thermal and Kinetic Analysis
- Parkinson's Disease Mechanisms and Treatments
- Spatial Cognition and Navigation
- Schizophrenia research and treatment
- Neuroscience and Neuropharmacology Research
- Health, Environment, Cognitive Aging
Nanjing Medical University
2018-2025
Zhongda Hospital Southeast University
2013-2025
Nanjing Drum Tower Hospital
2022-2025
Nanjing University
2022-2025
Shandong Academy of Agricultural Sciences
2025
Chinese Academy of Sciences
2023-2025
Aerospace Information Research Institute
2025
Nanjing University of Science and Technology
2020-2024
Nanjing Brain Hospital
2018-2024
Artificial Intelligence in Medicine (Canada)
2024
Nitrate electroreduction (NO3RR) holds promise as an energy-efficient strategy for the removal of toxic nitrate to restore natural nitrogen cycle and mitigate adverse impacts caused by overfertilization from suboptimal agricultural practices. However, existing catalysts suffer limited electrocatalytic activity, poor selectivity, inadequate durability, low scalability. To address this quadrilemma, in study, we developed a cost-effective layered double hydroxide (LDH) electrocatalyst with...
Abstract The recent successful growth of MoSi 2 N 4 and WSi monolayers led to the discovery a new class two‐dimensional (2D) MA Z materials with no known 3D layered allotropes, which renders great possibilities integrate diverse properties by proper design sandwiched “MZ ” building blocks “A−Z” passivation layers. In this work, dynamic stability, electronic properties, surface reactivity family, in M is Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, A refers Si or Ge, N, P As, theoretically probed. Among...
BACKGROUNDMajor depressive disorder (MDD) and posttraumatic stress (PTSD) are highly comorbid exhibit strong correlations with one another. We aimed to investigate mechanisms of underlying relationships between PTSD 3 kinds phenotypes, namely, MDD, depressed affect (DAF), depression (DEP, including both MDD the broad definition depression).METHODSGenetic phenotypes were tested using linkage disequilibrium score regression. Polygenic overlap analysis was used estimate shared trait-specific...
Subjective cognitive decline (SCD) and amnestic mild impairment (aMCI) are known as the preclinical early stage of Alzheimer's disease (AD). The dorsal attention network (DAN) is mainly responsible for "top-down" process. However, previous studies focused on single functional modality limited structure. This study aimed to investigate multimodal alterations DAN in SCD aMCI assess their diagnostic value early-stage AD.Resting-state magnetic resonance imaging (MRI) was carried out measure...
Alzheimer's disease (AD) is a prevalent form of dementia that affects an estimated 32 million individuals globally. Identifying early indicators vital for screening at-risk populations and implementing timely interventions. At present, there urgent need sensitive biomarkers to screen at risk AD. Among all sensory biomarkers, olfaction currently one the most promising Olfactory dysfunction signifies decline in ability detect, identify, or remember odors. Within spectrum AD, impairment...
Abstract Objective The objective of this study was to investigate underlying mechanisms long‐term effective weight loss after laparoscopic sleeve gastrectomy (LSG) and effects on the medial orbitofrontal cortex (mOFC) cognition. Methods A total 18 individuals with obesity (BMI ≥ 30 kg/m 2 ) underwent LSG. Clinical data, cognitive scores, brain magnetic resonance imaging scans were evaluated before LSG 12 months We employed voxel‐based morphometry analysis seed‐based resting‐state functional...
Background: The early progression continuum of Alzheimer's disease (AD) has been considered to advance through subjective cognitive decline (SCD), non-amnestic mild impairment (naMCI), and amnestic (aMCI). Altered functional connectivity (FC) in the default mode network (DMN) is regarded as a hallmark AD. Furthermore, DMN can be divided into two subnetworks, anterior posterior subnetworks. However, little known about distinct disruptive patterns subsystems across preclinical AD spectrum....
Background Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia. Amnestic MCI (aMCI) non-amnestic are the two subtypes of with former having a higher risk for progressing to Alzheimer's disease (AD). Compared healthy elderly adults, individuals have specific functional alterations in salience network (SN). However, no consistent results documenting these changes. This meta-analysis aimed investigate SN aMCI. Methods: We systematically searched PubMed,...
Background States of depression are associated with increased sensitivity to negative events. For this novel study, we have assessed the relationship between number depressive episodes and dysfunctional processing emotional facial expressions. Methodology/Principal Findings We used a visual oddball paradigm manipulate information while event-related brain potentials were recorded in 45 patients first episode major (F-MD), 40 recurrent (R-MD), 46 healthy controls (HC). Compared HC group, F-MD...
Abstract Altered function of the medial temporal lobe (MTL) is a valuable indicator conversion from amnestic mild cognitive impairment (aMCI) to Alzheimer’s disease. This study delineate functional circuitry multiple subdivisions parahippocampal gyrus and hippocampus (HIP) examine how this knowledge contributes more principled understanding contributions its subregions memory in aMCI. The connectivity (FC) analysis was performed 85 aMCI 129 healthy controls. demonstrated distinct disruptive...
Hippocampal subregions (HIPsub) and their network connectivities are generally aberrant in patients with subjective cognitive decline (SCD). This study aimed to investigate whether repetitive transcranial magnetic stimulation (rTMS) could ameliorate HIPsub connectivity by modulating one node of SCD. In the first cohort, functional (FC) three (i.e., hippocampal emotional, cognitive, perceptual regions: HIPe, HIPc, HIPp) were analyzed so as identify alterations associated Afterwards, a support...
Abstract Objective This study aimed to investigate the characteristic of brain structural connections in glioma patients and further evaluate relationship between changes white matter tracts cognitive decline. Methods retrospective included a total 35 subjects with 14 demographically matched healthy controls, who underwent diffusion tensor imaging scans formal neuropsychological assessment tests. Fractional anisotropy (FA) values were derived from atlas‐based analysis compare group...
We aimed to investigate the genetic mechanisms associated with coronavirus disease of 2019 (COVID-19) outcomes in host and evaluate possible associations between smoking drinking behavior three COVID-19 outcomes: severe COVID-19, hospitalized infection. described genomic loci risk genes outcomes, followed by functional analyses genes. Then, a summary data-based Mendelian randomization (SMR) analysis, transcriptome-wide association study (TWAS) were performed for dataset. A two-sample (MR)...