A5101537643- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Hepatitis Viruses Studies and Epidemiology
- Respiratory and Cough-Related Research
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Immune responses and vaccinations
- Diphtheria, Corynebacterium, and Tetanus
- Academic Writing and Publishing
- Immunodeficiency and Autoimmune Disorders
- Virology and Viral Diseases
- Pediatric health and respiratory diseases
- Social Media in Health Education
- Peripheral Neuropathies and Disorders
- Infectious Encephalopathies and Encephalitis
- COVID-19 and healthcare impacts
- Viral Infections and Immunology Research
- COVID-19 epidemiological studies
- Toxin Mechanisms and Immunotoxins
- Antibiotic Use and Resistance
Zhejiang Center for Disease Control and Prevention
2020-2025
Advanced Materials Enterprises (China)
2019
While parents were traditionally the main reservoir for infant pertussis, transmission sources may have shifted with China's multi-child policy. Our study aimed to investigate household patterns and clinical characteristics of pertussis in infants. We investigated patients (aged ≤ 6 months) diagnosed at a hospital (Children's Hospital Zhejiang University School Medicine) from 1 January May 2024. The laboratory diagnosis was confirmed through bacterial culture. collected basic information...
Following the rollout of a booster campaign to promote immunity against COVID-19 in China, this study aimed assess hesitancy among adults who were fully vaccinated with primary doses across Zhejiang Province. Firstly, modified 5C scale developed by German research team was assessed for reliability and validity via pre-survey Then, 30-item questionnaire established conduct online offline surveys during 10 November 15 December 2021. Demographic characteristics information on previous...
Pertussis is one of the top 10 diseases children under years age, and few vaccine-preventable who on a rise in China recent years; however, true burden pertussis, including age-stratified incidence risk factors severe sequelae, are under-recognised. We aim to estimate health laboratory-confirmed pertussis by age groups, considering setting illness onset (ie, community, outpatient inpatient), Chinese population (~2.23 million total) at two sites. This paper describes study design 1-year,...
This study aimed to determine the level of viral hepatitis knowledge as well self-awareness B virus surface antigen (HBsAg) positive individuals, provide data support for next steps in prevention and control. We conducted a cross-sectional survey assess among general population aged 15–69 years Zhejiang Province, China. A total 3,626 individuals were surveyed with 10 questions. The participants is reflected by scores from survey. Adequate was defined score ≥ 6. rate ratio number adequate...
In 2016, China officially proposed for the first time that infants born to HBsAg-positive mothers should be tested HBsAg and anti-HBs 1-2 months after their third dose of HepB, also known as post-vaccination serological testing programme. This study aimed systematically evaluate implementation influencing factors PVST further reduce HBV infection risk in improve protective effect HepB greatest extent. A prospective observational was conducted investigate interruption MTCT hepatitis B....
This study aimed to investigate the non-prescription use of antibiotics for cough among children under 5 years in China.A community-based cross-sectional survey.A face-to-face interview based on a standard questionnaire community from October December 2019.A total 3102 age were enrolled with probability proportionate size sampling method. The children's caregivers provided responses as their agents.Cough past month, after cough.1211 reported have month. Of these, 40.2% (487/1211) medicated...
Editorials and commentaries (E/C) are common article categories usually solicited by editors in many journals. However, not all experts accept invitation for an E/C essay a variety of reasons. We conducted this study to explore the potential influence factors contributing whether write is accepted specialist.Data invited from journals AME Publishing Company between January 1st, 2018 December 31st, were retrospectively identified consecutively collected. Acceptance writing was recorded as...
Background: Measles and rubella are vaccine-preventable diseases targeted for elimination in most World Health Organization regions, China is considered to have momentum towards measles elimination. Therefore, this study aimed assess the population immunity levels against Zhejiang Province order provide valuable insights informing future public health measures contributing ongoing global campaign these diseases. Materials methods: A cross-sectional serological survey was conducted 2022....
The resurgence of pertussis in China underscores the urgency active surveillance to complement passive system.
Hospitalization is most common for severe pertussis cases and those with serious complications caused by pertussis. In mainland China, the immunization program consists of primary vaccinations at 3, 4, 5 months, followed a booster 18 months DTaP. It remains uncertain whether first dose 3 rather than 6 weeks as WHO recommended, may increase disease burden, delayed lead to lagged protection. This study aimed determine hospitalization rates active surveillance in shedding light on strategies...
To evaluate the cost-effectiveness of post-vaccination serologic testing (PVST) plus active-passive immunoprophylaxis infants born to hepatitis B surface antigen (HBsAg)-positive mothers, a Markov model was constructed by R 4.0.1 compare current strategy (three-dose HepB HBIG) and PVST (post-vaccination strategy) for HBsAg-positive mothers. Costs utility scores were assessed from field survey. Other inputs extracted published literature unpublished data Zhejiang provincial center disease...
Objective: To analyze the willingness of receiving influenza vaccine and its influencing factors among health care workers (HCWs) in Yangtze River Delta region from 2020 to 2021. Methods: Convenient sampling method was adopted. From July March 2021, 76 hospitals Jiangsu, Zhejiang, Anhui Shanghai provinces were selected according hospital level job position, a questionnaire survey conducted on vaccination. Logistic regression model used vaccination intention. Results: A total 1 332 HCWs...
Objective: To analyze the epidemiological characteristics and spatiotemporal clustering of hepatitis A in Zhejiang Province from 2010 to 2019. Methods: The data incidence 2019 were collected infectious disease surveillance system China Information System for Disease Control Prevention. ArcGIS 10.7 software was used spatial autocorrelation analysis. SaTScan 9.6 scanning SPSS 25.0 additional Results: has reported 5 465 cases 2010-2019 years, with an average annual rate 1.00/100 000,...
Abstract Background: Cough is a common symptom in childhood and an important circumstance of inappropriate antibiotic use. This study aimed to investigate the non-prescription use antibiotics for cough among children aged under 5 years. Methods: We conducted community-based survey under-5 Yiwu, China from October November 2019. The subjects were enrolled 14 townships using two-stage stratified sampling procedure. Detailed information was collected through face-to-face interview based on...
Estimating the actual real-world effectiveness of vaccine is an essential part post-marketing evaluation. This regression discontinuity design (RDD) using observational data designed to quantify effect intervention when eligibility for based on a defined cutoff as age, making it suited estimate effects. approach can avoid high cost and ethical issues; overcome difficulties in organization practice process randomized controlled trials, which leads higher level causal inference evidence more...
Background: Sabin inactivated and bivalent oral poliovirus vaccine (sIPV, bOPV) were commonly used in China since 2016. We conducted a continuous open-label, randomised, controlled phase 4 trial to assess immune persistence following sequential immunisation with sIPV or bOPV, immunogenicity safety of booster dose children aged years.Methods: Participants from previous clinical three different schedules (I) bOPV (B) at ages 2, 3, months (Groups I-B-B, I-I-B, I-I-I) 2017 followed-up. The...