Zhiping Chen

ORCID: 0000-0002-3351-5831
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About
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Research Areas
  • Contact Dermatitis and Allergies
  • Gastric Cancer Management and Outcomes
  • Allergic Rhinitis and Sensitization
  • Respiratory viral infections research
  • Occupational exposure and asthma
  • Viral Infections and Immunology Research
  • Adaptive optics and wavefront sensing
  • Food Allergy and Anaphylaxis Research
  • Cell Adhesion Molecules Research
  • Viral Infections and Vectors
  • Liver Disease Diagnosis and Treatment
  • Catalytic Processes in Materials Science
  • Radio Astronomy Observations and Technology
  • Optical Systems and Laser Technology
  • Hepatitis B Virus Studies
  • Antenna Design and Optimization
  • Solar and Space Plasma Dynamics
  • Viral gastroenteritis research and epidemiology
  • Radiomics and Machine Learning in Medical Imaging
  • Geophysics and Gravity Measurements
  • Catalysis and Oxidation Reactions
  • Ionosphere and magnetosphere dynamics
  • Platelet Disorders and Treatments
  • Stellar, planetary, and galactic studies
  • Spacecraft Design and Technology

Jiangxi University of Technology
2025

East China University of Technology
2020-2025

Ministry of Natural Resources
2022-2025

China Geological Survey
2025

Nankai University
2025

Zhejiang Center for Disease Control and Prevention
2014-2024

Sixth Affiliated Hospital of Sun Yat-sen University
2021-2024

Sun Yat-sen University
2021-2024

Shandong University
2024

First Affiliated Hospital of Jiangxi Medical College
2022-2024

The firm adhesion and transplatelet migration of leukocytes on vascular thrombus are both dependent the interaction leukocyte integrin, Mac-1, a heretofore unknown platelet counterreceptor. Here, we identify counterreceptor as glycoprotein (GP) Ibα, component GP Ib-IX-V complex, von Willebrand factor (vWf) receptor. THP-1 monocytic cells transfected that express Mac-1 adhered to Ibα–coated wells. Inhibition studies with monoclonal antibodies or receptor ligands showed involves I domain...

10.1084/jem.192.2.193 article EN The Journal of Experimental Medicine 2000-07-10

Evidence of whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes disease 2019 (COVID-19), can be transmitted as an aerosol (ie, airborne) has substantial public health implications.To investigate potential transmission routes SARS-CoV-2 infection with epidemiologic evidence from a COVID-19 outbreak.This cohort study examined community outbreak in Zhejiang province. On January 19, 2020, 128 individuals took buses (60 [46.9%] bus 1 and 68 [53.1%] 2) on...

10.1001/jamainternmed.2020.5225 article EN JAMA Internal Medicine 2020-09-01

AMP-activated protein kinase (AMPK) is a metabolic stress-sensing responsible for coordinating metabolism and energy demand. In rodents, exercise accelerates fatty acid metabolism, enhances glucose uptake, stimulates nitric oxide (NO) production in skeletal muscle. AMPK phosphorylates inhibits acetyl-coenzyme A (CoA) carboxylase (ACC) GLUT-4 translocation. It has been reported that human muscle malonyl-CoA levels do not change response to exercise, suggesting other mechanisms besides...

10.1152/ajpendo.2000.279.5.e1202 article EN AJP Endocrinology and Metabolism 2000-11-01

C-reactive protein (CRP), an acute-phase reactant long considered merely innocent bystander in the inflammatory process, is now recognized as a powerful predictor of cardiovascular events. Emerging vitro evidence suggests that CRP may have direct proinflammatory and prothrombotic effects on monocytes endothelial cells. To determine whether directly modulates vascular cell function vivo, we subjected wild-type mice, which do not express CRP, human CRP-transgenic (CRPtg) mice to 2 models...

10.1161/01.cir.0000085568.13915.1e article EN Circulation 2003-07-22

Leukocyte-platelet interactions are critical in the initiation and progression of atherosclerosis as well restenosis. Although leukocyte integrin Mac-1 (alphaMbeta2, CD11b/CD18) has been implicated firm adhesion transmigration leukocytes at sites platelet deposition, precise alphaMbeta2 counterligand responsible for mediating adhesion-strengthening between neutrophils platelets vivo not previously identified.Our previous studies have established P201-K217 sequence alphaMI domain binding site...

10.1161/circulationaha.105.571315 article EN Circulation 2005-11-01

Adhesion and signaling by integrins require their dynamic association with nonintegrin membrane proteins. One such protein, the glycolipid-anchored urokinase receptor (uPAR), associates modifies function of β<sub>2</sub>-integrin Mac-1 (CD11b/CD18). In this study, a critical non-I-domain binding site for uPAR on CD11b (M25; residues 424–440) is identified homology phage display peptide known to bind uPAR. Recombinant soluble cells expressing bound immobilized M25, being promoted blocked but...

10.1074/jbc.275.14.10228 article EN cc-by Journal of Biological Chemistry 2000-04-01

10.1016/s0091-6749(98)70188-5 article EN Journal of Allergy and Clinical Immunology 1998-01-01

The Tianlai Dish Pathfinder Array is a radio interferometer designed to test techniques for 21~cm intensity mapping in the post-reionization universe as means measuring large-scale cosmic structure. It performs drift scans of sky at constant declination. We describe design, calibration, noise level, and stability this instrument based on analysis about $\sim 5 \%$ 6,200 hours on-sky observations through October, 2019. Beam pattern determinations using drones transit bright sources are good...

10.1093/mnras/stab1802 article EN Monthly Notices of the Royal Astronomical Society 2021-07-05

Postoperative infected wound complications caused by residual tumor cells, bacterial biofilms, and drug-resistant bacteria have become the main challenge in postsurgical skin regeneration. Herein, a bionic cellulose nanocrystal (CNC)-based situ intelligent dressing with near-infrared (NIR)-, temperature-, pH-responsive functions was designed using NIR-responsive CNC as network skeleton, dynamic imine bonds between dialdehyde nanocrystals doxorubicin, chitosan oligosaccharide switch,...

10.1021/acsami.2c13203 article EN ACS Applied Materials & Interfaces 2022-11-14

We have previously reported that 5 days of a high-fat diet followed by 1 day high-carbohydrate intake (Fat-adapt) increased rates fat oxidation and decreased muscle glycogenolysis during submaximal cycling compared with consumption an isoenergetic (HCHO) for 6 (Burke et al. J Appl Physiol 89: 2413-2421, 2000; Stellingwerff Am Endocrinol Metab 290: E380-E388, 2006). To determine potential mechanisms underlying shifts in substrate selection, eight trained subjects performed Fat-adapt HCHO. On...

10.1152/japplphysiol.90540.2008 article EN Journal of Applied Physiology 2008-09-19

Polymorphisms of genes encoding components the vitamin D pathway including receptor (VDR) and binding protein (DBP) have been widely investigated because complex role played by in cancer tumorogenesis. In this study, we association between VDR DBP gene polymorphisms HBV-related HCC risk a Chinese population.Study subjects were divided into three groups: 184 HBV patients with HCC, 296 without 180 healthy controls. The rs2228570, rs3782905 rs7041 genotyped using PCR-RFLP rs11568820...

10.1371/journal.pone.0116026 article EN cc-by PLoS ONE 2014-12-26

Abstract Insights into the relationship between crystal planes of metal oxides and catalytic activity oxygen evolution reaction (OER), reduction (ORR), hydrogen (HER) are essential for developing efficient renewable energy technologies. Herein, spinel Co 3 O 4 nanomaterials were synthesized controllably with specified morphologies nanocubes, nanosheets, nanoplates different exposed {100}, {110}, {111}, respectively. The effects on OER, ORR, HER subsequently investigated in alkaline media....

10.1002/celc.201701302 article EN ChemElectroChem 2018-01-22
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