A5075575530- Glycosylation and Glycoproteins Research
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Cancer Immunotherapy and Biomarkers
- Enzyme Structure and Function
- Selenium in Biological Systems
- Transcranial Magnetic Stimulation Studies
- Circadian rhythm and melatonin
- Muscle activation and electromyography studies
- Cancer Research and Treatments
- Neurological disorders and treatments
- Lung Cancer Treatments and Mutations
- Stress Responses and Cortisol
- Mercury impact and mitigation studies
- Lung Cancer Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Cancer, Hypoxia, and Metabolism
- Light effects on plants
- Arsenic contamination and mitigation
- Barrier Structure and Function Studies
- Caveolin-1 and cellular processes
- Angiogenesis and VEGF in Cancer
- Studies on Chitinases and Chitosanases
- Toxoplasma gondii Research Studies
Hunan Normal University
2025
Hunan Provincial People's Hospital
2025
Sichuan University
2012-2024
Hong Kong Polytechnic University
2023-2024
Union Hospital
2024
Wenzhou Medical University
2024
Huazhong University of Science and Technology
2024
West China Hospital of Sichuan University
2023
Beijing National Laboratory for Molecular Sciences
2022
Peking University
2022
High tumor mutational burden (TMB-H) is correlated with enhanced objective response rate (ORR) and progression-free survival (PFS) for certain cancers receiving immunotherapy. This study aimed to investigate the safety efficacy of toripalimab, a humanized programmed death-1 (PD-1) antibody, in advanced gastric cancer (AGC), predictive benefit TMB PD-L1.
<title>Abstract</title> For half a century, cervical auscultation has been proposed as novel method for screening aspiration in patients with dysphagia. Most of the previous studies focused on effects food consistency, volume, and head-neck position swallowing sounds. However, standardized liquid viscosity texture sounds are not fully understood due to lack uniform bolus preparation. Currently, there is insufficient guidance literature appropriate liquids foods training, also using acoustic...
A consensus treatment strategy for esophageal squamous cell carcinoma (ESCC) patients who recur after definitive radiochemotherapy/radiotherapy has not been established. This study compared the outcomes in ESCC underwent salvage surgery, chemoradiation (CRT) or best supportive care (BSC) local recurrence. Ninety-five with clinical stage I to III had completely responded initial radiochemotherapy radiotherapy alone and developed recurrence were enrolled this study. Fifty-one of them received...
To investigate the knowledge, attitudes and practices surrounding occupational blood-borne pathogen exposure amongst dental students at two Chinese schools, as well important factors that are associated with their career choice towards infected patients.The study was conducted using a student self-administered questionnaire from March to June 2013 schools. Chi-square tests multivariable logistic regression were used compare categorical variables identify related attitudes.One hundred...
Podosomes and tight junctions (TJs) are subcellular compartments that both exist in endothelial cells localize at cell surfaces. In contrast to the well-characterized role of TJs maintaining cerebrovascular integrity, specific function podosomes remains unknown. Intriguingly, we discovered cross-talk between human brain cells. Tight junction scaffold proteins ZO-1 ZO-2 response phorbol-12-myristate-13-acetate treatment. We found ZO essential for podosome formation function. Rather than being...
Abstract The ventricular zone (VZ) is made up of adult neural stem cells (NSCs) and multi-ciliated ependymal (EPCs). Both NSCs EPCs are derived from radial glial (RGCs). To date, the transcriptomic dynamics molecular mechanisms guiding cell fate commitment during differentiation remain poorly understood. In this study, we analysed developing VZ at single-cell resolution identified three distinct cellular states RGCs: bipotent progenitor (bGPCs), neonatal NSC-neuroblasts (nNSC-NBs) (nEPCs)....
Abstract Decontamination of the toxic selenium compound, selenite (Se(IV)) and selenate (Se(VI)), from wastewater is imperative for environmental protection. Efficient approaches to remove Se(IV) Se(VI) are in urgent needs. In this work, an accessible adsorbent Fe–OOH–bent was prepared applied removal wastewater. The batch experimental results demonstrate that exhibits high adsorption capacities 5.01 × 10 −4 2.28 mol/g respectively, which higher than most reported bentonite based materials,...
Expansions of ATTTT and ATTTC pentanucleotide repeats in the human genome are recently found to be associated with at least seven neurodegenerative diseases, including spinocerebellar ataxia type 37 (SCA37) familial adult myoclonic epilepsy (FAME) types 1, 2, 3, 4, 6, 7. The formation non-B DNA structures during some biological processes is thought as a causative factor for repeat expansions. Yet, structural basis these pyrimidine-rich expansions remains elusive. In this study, we...
Abstract Dexamethasone is widely used for treating pregnant diseases. However, lots of studies have confirmed that prenatal dexamethasone exposure (PDE) could increase the risk offspring multiple The purpose this study was to elucidate intrauterine epigenetic mechanism adrenal developmental programming, and explore early warning marker in peripheral blood mononuclear cells (PBMC). We found morphological functional changes before after birth PDE male rats, which were performed as decreases...