A5041112612- Nutritional Studies and Diet
- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Nutrition, Genetics, and Disease
- Fatty Acid Research and Health
- GDF15 and Related Biomarkers
- Protein Hydrolysis and Bioactive Peptides
- Diet, Metabolism, and Disease
- Renal Diseases and Glomerulopathies
- Autoimmune Bullous Skin Diseases
- Phytoestrogen effects and research
- Obesity, Physical Activity, Diet
- Meat and Animal Product Quality
- Consumer Attitudes and Food Labeling
- Nutrition and Health in Aging
- Vasculitis and related conditions
- Biochemical Analysis and Sensing Techniques
Agroscope
2021-2023
Wageningen University & Research
2020-2023
Colorado State University
2018-2022
Federal Department of Economic Affairs, Education and Research
2021
Federal Office for Agriculture
2021
Abnormal cholesterol in childhood predicts cardiovascular disease (CVD) risk adulthood. Navy beans and rice bran have demonstrated efficacy regulating blood lipids adults children; however, their effects on modulating the child plasma metabolome has not been investigated warrants investigation. A pilot, randomized-controlled, clinical trial was conducted 38 children (10 ± 0.8 years old) with abnormal cholesterol. Participants consumed a snack for 4 weeks containing either: no navy bean or...
Humans have a long history of consuming fermented foods. However, their prevalence in human diets remains largely undetermined, and there is lack validated dietary assessment tools assessing the intake different products. This study aimed to identify foods consumed The Netherlands determine relative validity food frequency questionnaire (FFQ) compared multiple 24-h recalls for estimating intake.The validation population consisted 809 participants (53.1 ± 11.9 years) from Dutch observational...
Identification of food intake biomarkers (FIBs) for fermented foods could help improve their dietary assessment and clarify associations with cardiometabolic health. We aimed to identify novel FIBs in the plasma urine metabolomes 246 free-living Dutch adults using nontargeted LC-MS GC-MS. Furthermore, between identified metabolites several risk factors were explored. In total, 37 corresponding intakes coffee, wine, beer (none cocoa, bread, cheese, or yoghurt intake). While some these...
Milk-derived free fatty acids (FFAs) may act as both biomarkers of intake and metabolic effect. In this study we explored associations between different types dairy consumption, a selection milk-derived acids, cardiometabolic disease (CMD) risk factors.Sixty-seven FFAs were quantified in the plasma 131 free-living Dutch adults (median 60 years) using gas chromatography-flame ionization detector. Intakes foods groups assessed food frequency questionnaire. Twelve CMD factors analyzed. Multiple...
Blood lipids have served as key biomarkers for cardiovascular disease (CVD) risk, yet emerging evidence indicates metabolite profiling might reveal a larger repertoire of small molecules that reflect altered metabolism, and which may be associated with early risk. Inadequate micronutrient status also drive or exacerbate CVD risk factors emerge during childhood. This study aimed to understand relationships between serum lipid levels, the plasma metabolome, in 38 children (10 ± 0.8 years) at...
Studies examining associations between self-reported dairy intake and health are inconclusive, but biomarkers hold promise for elucidating such relationships by offering objective measures of dietary intake. Previous human intervention studies identified several foods in blood urine using non-targeted metabolomics. We evaluated the robustness these a free-living cohort Netherlands both single- multi-marker approaches. Plasma from 246 participants (54 ± 13 years) who completed food frequency...
Dietary exposure biomarkers are needed for advancing knowledge on healthy foods. This study examined navy beans and rice bran in children adults. Plasma, urine, stool, foods from dietary intervention studies were analyzed by metabolomics. A total of 38 49 adults assessed after consuming and/or 2-, 4-, 6-, or 12 weeks. From the 138-175 metabolites modulated diet, 11 targeted quantification. Trigonelline pipecolate concentrations increased adult plasma 4 weeks compared to baseline. Increased...
All living creatures need to eat. Eating a variety of different healthy foods in moderate amounts is important. How do we know which are healthy? Researchers can compare the consumed by and unhealthy people asking what how much they Unfortunately, cannot always remember eat, makes it difficult figure out healthy. Recently, researchers discovered that group research tools called omics could help. When building blocks food broken down into small compounds metabolites. With laboratory...