Virginia Osborn

ORCID: 0000-0001-8700-4861
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About
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Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • Advanced Radiotherapy Techniques
  • Head and Neck Cancer Studies
  • Advances in Oncology and Radiotherapy
  • Colorectal and Anal Carcinomas
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Management of metastatic bone disease
  • Salivary Gland Tumors Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Glioma Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Head and Neck Surgical Oncology
  • Ear and Head Tumors
  • COVID-19 and healthcare impacts
  • Diversity and Career in Medicine
  • Viral-associated cancers and disorders
  • Cervical Cancer and HPV Research
  • Endometrial and Cervical Cancer Treatments
  • Meningioma and schwannoma management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Healthcare professionals’ stress and burnout
  • Cancer Treatment and Pharmacology

Exeter Hospital
2024

Massachusetts General Hospital
2022

SUNY Downstate Health Sciences University
2015-2021

Elmhurst Hospital Center
2019-2021

Icahn School of Medicine at Mount Sinai
2020-2021

Mount Sinai Queens
2019-2021

Memorial Sloan Kettering Cancer Center
2018-2020

State University of New York
2020

Summit Medical Group (United States)
2020

VA NY Harbor Healthcare System
2015-2018

Objectives/Hypothesis National Cancer Care Network guidelines suggest consideration of adjuvant radiation even for early stage adenoid cystic carcinoma the salivary glands. We used Data Base (NCDB) to analyze practice patterns and outcomes postoperative radiotherapy carcinomas. Study Design Retrospective NCDB review. Methods Patients with nonmetastatic parotid, submandibular, or another major gland from 2004 2012 were identified. Information was collected regarding receipt radiation. The...

10.1002/lary.26516 article EN The Laryngoscope 2017-02-14

Objective Using the National Cancer Database (NCDB), we investigated characteristics, outcomes, and benefits of adjuvant therapy for patients diagnosed with malignant salivary gland tumors between 2004 2012. Study Design Retrospective analysis. Setting NCDB. Subject Methods The cases a nonmetastatic major tumor who underwent resection 2012 were abstracted from Patients further included if they had pT1‐4NX‐1M0 high‐grade disease or pT3‐4NX‐0M0 pT1‐4N1M0 low‐grade disease. identified as having...

10.1177/0194599817717661 article EN Otolaryngology 2017-07-04

Given the paucity of esophageal small cell carcinoma (SCC) cases, there are few large studies evaluating this disease. In study, National Cancer Data Base (NCDB) was utilized to analyze clinical features, treatment, and survival patients with SCC in a large, population-based dataset. We selected diagnosed from 1998 2011. Patients were identified as having no chemotherapy alone, radiation ± sequential chemotherapy, concurrent chemoradiation, esophagectomy and/or radiation. Overall (OS)...

10.1111/dote.12487 article EN Diseases of the Esophagus 2016-11-01

The proportion of female trainees in radiation oncology has generally declined despite increasing numbers medical students; as a result, is among the bottom 5 specialties terms percentage applicants. Recently, social media been harnessed tool to bring recognition underrepresented groups within medicine and other fields. Inspired by wide-reaching campaign #ILookLikeASurgeon promote physicians, members Society for Women Radiation Oncology penned new hashtag launched #WomenWhoCurie on Marie...

10.1016/j.adro.2019.01.003 article EN cc-by-nc-nd Advances in Radiation Oncology 2019-01-30

Although the standard of care for glioblastoma remains maximal safe resection followed by chemoradiation, conflicting reports have emerged regarding importance time interval between these 2 treatments.To assess whether differences in duration surgery and initiation chemoradiation had an impact on overall survival (OS) a large hospital-based database.The National Cancer Database was queried to identify patients diagnosed with 2010 2012 treated chemoradiation. Patients who received biopsy only...

10.1093/neuros/nyx497 article EN Neurosurgery 2017-10-27

Purpose To analyze the utilization and fractionation of extreme hypofractionation via stereotactic body radiotherapy (SBRT) in treatment prostate cancer. Materials Methods Data was analyzed on men diagnosed with localized cancer between 2004–2012 treated definitive-intent radiation therapy, as captured National Cancer Database. This database is a hospital-based registry that collects an estimated 70% all malignancies United States. Results There were 299,186 patients identified, which 4,962...

10.3857/roj.2017.02026 article EN Radiation Oncology Journal 2017-06-30

Preclinical and clinical studies have suggested that aspirin (ASA) may exhibit antineoplastic activity. Particularly in prostate cancer, several reports ASA plays a role improved outcomes. Therefore, we studied the of uniquely African American population, which is known to harbor more aggressive biologically different disease compared general population.We identified 289 men with cancer who were treated definitive radiation therapy dose ≥7560 cGy. The median follow-up was 76 months....

10.5301/tj.5000424 article EN Tumori Journal 2015-09-30

Abstract Background The clinical significance of Epstein‐Barr virus (EBV) and human papillomavirus (HPV) infection in nasopharyngeal carcinoma (NPC) is unclear. Methods Three hundred forty three patients with NPC diagnosed between 1998 2017 treated at our institution were included. Chi‐square was used to identify characteristics associated viral status. Kaplan‐Meier methods estimate overall survival (OS) Cox proportional regression prognostic factors. Results Patients HPV‐associated more...

10.1002/hed.26245 article EN Head & Neck 2020-05-16

Standard of care treatment for anal squamous cell carcinoma (SCC) is concurrent chemoradiation (CRT). However, the necessity CRT over radiation alone T1-2N0 disease less certain.The National Cancer Database (NCDB) was queried to identify patients who received CRT, defined as initiation chemo and RT within 14 days each other, or (without any during initial phase) cT1-2N0M0 SCC anus. The cohort limited than 70 years old with Charlson-Deyo Comorbidity Index 0, receiving a dose range 4,500-5,940...

10.21037/jgo.2019.02.06 article EN Journal of Gastrointestinal Oncology 2019-07-09

Postoperative chemoradiotherapy (CRT) is considered standard of care in patients with locally advanced head and neck cancer positive margins and/or extracapsular extension (ECE).The National Cancer Data Base (NCDB) was queried to identify squamous cell carcinoma the stages III IVB disease or ECE diagnosed between 2004 2012 receiving postoperative radiotherapy (RT). Using univariable multivariable logistic Cox regression, we assessed for predictors CRT use covariables impacting overall...

10.1002/hed.25103 article EN Head & Neck 2018-02-16

Introduction This study aims to analyze the patterns of care, including fractionation and utilization, hypofractionated stereotactic ablative radiotherapy (SABR) in treatment hepatocellular carcinoma (HCC). Methods The National Cancer Database was queried for patients diagnosed with HCC from 2004 2014 treated SABR three, four, or five fractions 15-20Gy, 10-13Gy, 6-12Gy per fraction, respectively. Patients stage IV Charlson-Deyo Comorbidity Index > 0 were excluded order avoid bias...

10.7759/cureus.8675 article EN Cureus 2020-06-17

Purpose It is unknown whether there a benefit to starting androgen deprivation therapy (ADT) prior rather than concurrently with definitive radiation in men high-risk prostate cancer. We studied the National Cancer Data Base determine timing of ADT impacts survival. Methods Men diagnosed adenocarcinoma who received external beam (EBRT) dose 70-81 Gy along from 2004-2011 were included. Those started 42-90 days before EBRT identified as having neoadjuvant hormonal (N-HT) and those 14 their...

10.5301/tj.5000595 article EN Tumori Journal 2017-01-13

There have been numerous studies demonstrating how cancer patients are at an increased risk of mortality. Within New York City, our community hospital emerged as epicenter the first wave pandemic in spring 2020 and serves a unique population that is predominately uninsured, lower income, racially/ethnically diverse. In this single institution retrospective study, authors seek to investigate COVID-19 diagnosis, severity mortality with active diagnosis. Demographic, clinical characteristics,...

10.3390/curroncol29020098 article EN cc-by Current Oncology 2022-02-16

Abstract: Postmastectomy radiation therapy (PMRT) has long been utilized to improve locoregional control versus surgery alone, and recent decades have revealed a survival benefit for many higher risk patients based on tumor or nodal factors. During this time the landscape of cancer treatment evolved towards less invasive surgeries more effective chemotherapy—likewise, precise methods delivering also emerged, drastically reducing significant side effects compared with cruder historical...

10.21037/abs-20-120 article EN cc-by-nc-nd Annals of Breast Surgery 2021-06-16

Abstract Background: An IRB-approved single arm prospective multi-institution trial was designed to determine the efficacy and outcome of fraction 20 Gy intra-operative radiation therapy (IORT) using disposable balloon electronic brachytherapy at time breast conserving surgery for early-stage cancer (women least 40 years old, infiltrating ductal carcinoma [IDC] or in situ [DCIS], lesion no larger than 3 cm, pN0). Ipsilateral tumor recurrences (IBTR) median 5-year follow-up, primary protocol...

10.1158/1538-7445.sabcs23-po2-22-04 article EN Cancer Research 2024-05-02
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