- Advanced Radiotherapy Techniques
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Management of metastatic bone disease
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Endometrial and Cervical Cancer Treatments
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Ovarian cancer diagnosis and treatment
- Lung Cancer Treatments and Mutations
- Head and Neck Cancer Studies
- Advances in Oncology and Radiotherapy
- Endometriosis Research and Treatment
- Esophageal and GI Pathology
- Prostate Cancer Treatment and Research
- Esophageal Cancer Research and Treatment
- Cervical Cancer and HPV Research
- Prostate Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Climate Change and Health Impacts
- Gastric Cancer Management and Outcomes
- Glioma Diagnosis and Treatment
- Pelvic and Acetabular Injuries
Orlando Health
2013-2024
University of Florida Health
2014-2020
UF Health Cancer Center
2014-2020
The University of Texas MD Anderson Cancer Center
2010-2013
SUNY Downstate Health Sciences University
2008-2010
State University of New York
2010
The objective of this study was to analyze the impact on overall survival (OS) from addition postoperative radiation with or without chemotherapy after esophagectomy, using a large, hospital-based dataset.Previous retrospective studies have suggested an OS advantage for chemoradiation over surgery alone, although prospective data are lacking.The National Cancer Data Base queried select patients diagnosed stage pT3-4Nx-0M0 pT1-4N1-3M0 esophageal carcinoma (squamous cell adenocarcinoma) 1998...
Given the paucity of esophageal small cell carcinoma (SCC) cases, there are few large studies evaluating this disease. In study, National Cancer Data Base (NCDB) was utilized to analyze clinical features, treatment, and survival patients with SCC in a large, population-based dataset. We selected diagnosed from 1998 2011. Patients were identified as having no chemotherapy alone, radiation ± sequential chemotherapy, concurrent chemoradiation, esophagectomy and/or radiation. Overall (OS)...
Objective: To utilize the Surveillance, Epidemiology, and End Results Database to analyze clinical features, treatment, survival outcomes of patients with small cell carcinoma bladder in a large population-based sample. Because its rarity, prior reports are primarily limited single-institution studies. Methods: We identified any age who were diagnosed between 1988 2007. Kaplan-Meier Cox regression analysis used compare overall (OS) urinary bladder-specific survival. Results: A total 663...
Magnetic resonance-guided radiation therapy (MRgRT) utilization is rapidly expanding worldwide, driven by advanced capabilities including continuous intrafraction visualization, automatic triggered beam delivery, and on-table adaptive replanning (oART). Our objective was to describe patterns of 0.35Tesla(T)-MRgRT (MRIdian) in the United States (US) among early adopters this novel technology.Anonymized administrative data from all US MRIdian treatment systems were extracted for patients...
Despite advances in endocrine therapy (ET), metastatic estrogen receptor positive breast cancer (BrCA) remains incurable. Though the mechanisms of resistance to ET have been studied extensively, anatomic pattern disease progression poorly characterized. The purpose this study was characterize for patients receiving BrCA. records 108 with BrCA who progressed on were reviewed. Progression characterized as follows: diffuse progression, greater than 3 sites; oligoprogression, fewer sites prior...
With the implementation of MR-LINACs, real-time adaptive radiotherapy has become a possibility within clinic. However, process adapting patient's plan is time consuming and often requires input from entire clinical team, which translates to decreased throughput limited patient access. In this study, authors propose simulate workflow address these inefficiencies in staffing throughput. Two physicians, three radiation therapists (RTT), research fellow each adapted bladder bowel contours for 20...
Prior studies have suggested that men with prostate cancer and psychiatric disorders (+Psy) worse outcomes compared those without (-Psy), particularly due to delayed diagnosis or reduced access definitive treatment. In the current study, toxicity of who were primarily diagnosed through prostate-specific antigen screening underwent treatment external beam radiation was investigated. The charts 469 from 2003 2010 reviewed. presence +Psy based on a Diagnostic Statistical Manual Mental...
Postoperative chemoradiotherapy (CRT) is considered standard of care in patients with locally advanced head and neck cancer positive margins and/or extracapsular extension (ECE).The National Cancer Data Base (NCDB) was queried to identify squamous cell carcinoma the stages III IVB disease or ECE diagnosed between 2004 2012 receiving postoperative radiotherapy (RT). Using univariable multivariable logistic Cox regression, we assessed for predictors CRT use covariables impacting overall...
The aim of the following study is to analyze long-term results veterans treated with dose escalated radiation therapy for prostate cancer.This retrospective analyzed 469 patients who were between 2003 and 2010 a minimum 7560 cGy cancer at New York Harbor Department Veterans Affairs. Biochemical failure-free survival (bFFS) distant metastatic-free (DMFS) compared using Kaplan-Meier method. Univariate multivariate Cox Regression used measure impact covariates on biochemical control.The median...
We analyzed outcomes of patients with prostate cancer undergoing either radical retropubic prostatectomy (RRP) +/- salvage radiation or definitive therapy (RT) androgen deprivation.From 2003-2010 there were 251 who underwent RRP and 469 received RT (≥7,560 cGy) for cancer. Kaplan-Meier analysis was performed the log-rank test to compare biochemical control (bCR), distant metastatic-free survival (DMPFS), cancer-specific (PCSS) between two groups.The median follow-up 70 months 61.3% men...