A5048072937- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Breast Lesions and Carcinomas
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Endometrial and Cervical Cancer Treatments
- Breast Implant and Reconstruction
- Ovarian cancer diagnosis and treatment
- Cancer, Lipids, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Microbial Inactivation Methods
- Radiation Therapy and Dosimetry
- Radiation Effects and Dosimetry
- BRCA gene mutations in cancer
- Renal cell carcinoma treatment
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Radiopharmaceutical Chemistry and Applications
- Economic and Financial Impacts of Cancer
- Genital Health and Disease
- Urologic and reproductive health conditions
- Inflammatory Biomarkers in Disease Prognosis
Memorial Sloan Kettering Cancer Center
2024-2025
Cornell University
2014-2024
Weill Cornell Medicine
2016-2024
Presbyterian Hospital
2014-2024
New York Hospital Queens
2014-2024
NewYork–Presbyterian Hospital
2014-2024
M. P. Shah Medical College
2021
The University of Texas MD Anderson Cancer Center
2008-2011
Houston Methodist
2004
Methodist Hospital
2004
Stereotactic body radiotherapy is a hypofractionated, cost-effective treatment option for localized prostate cancer.To characterize US national trends and the clinical socioeconomic factors associated with use of stereotactic in cancer.This retrospective cohort study used data collected by National Cancer Database to assess among 106 926 men diagnosed as having cancer from 2010 2015 who underwent definitive this therapy. The initial analysis was performed between January February 2018, final...
Abstract Mast cells and macrophages infiltrate healing myocardial infarcts may play an important role in regulating fibrous tissue deposition extracellular matrix remodelling. This study examined the time‐course of macrophage mast cell accumulation studied histological characteristics protease expression profile a canine model experimental infarction. Although were more numerous than infarct granulation tissue, density decreased during maturation scar, whereas numbers remained persistently...
TPS4604 Background: The treatment for patients with metastatic RCC is evolving. current standard of care presenting de novo disease combination immunotherapy (IO)-based treatment. At the time this shift in systemic strategy, role immediate cytoreductive nephrectomy has also been flux. For disease, there a towards initiation upfront rather than nephrectomy. SABR highly focused radiation technique that delivers high dose over limited number fractions. SAMURAI trial seeks to evaluate as an...
24 Background: The number of prostate cancer cases globally is projected to double from 2020 2040. However, significant global variation exists in incidence and mortality. A more specific understanding health system levers may inform planning. Therefore, we used data the World Health Organization (WHO), Bank, Directory Radiotherapy Centres (DIRAC), United Nations Development Programme (UNDP), International Agency for Research on Cancer (IARC) evaluate predictors outcomes globally. Methods:...
352 Background: The incidence of regional lymph node metastases at diagnosis is approximately 15%. Androgen deprivation therapy (ADT) with radiotherapy (RT) remains a standard treatment option, but long-term effects and outcomes are understudied. Methods: Data was retrospectively collected from 304 subjects radiographic node-positive prostate cancer treated RT 2014-2024. Covariates include use androgen receptor signaling inhibitors (ARSI), brachytherapy boost to primary disease in prostate,...
387 Background: Level 1 evidence supports treatment of high-risk and node positive PCa using 4-9 weeks radiotherapy (RT) combined with 18-36 months androgen deprivation therapy (ADT) or without abiraterone acetate plus prednisone (AAP). While effective, some cancers recur, this prolonged is associated inconvenience variable morbidity. We aimed to determine whether the biological synergy stereotactic body (SBRT) a 6-month combination ADT, AAP, PARP inhibitor niraparib, could enable shorter...
Introduction: Acromioclavicular joint (ACJ) injuries are prevalent among young, active individuals and account for a significant proportion of shoulder girdle collision sports injuries. The Rockwood classification system categorizes these from Type I to VI, guiding treatment conservative management surgical intervention. Despite various techniques, including the Fiber-loop Endobutton method, failure rates, complications remain concern, particularly in cases post-operative instability. Case...
Importance Initial management of intermediate-risk prostate cancer is evolving, with no clear recommendation for treatment. Data on utilization active surveillance patients newly diagnosed may help clarify emerging trends. Objective To further characterize US national trends initial cancer. Design, Setting, and Participants This cohort study included from January 1, 2010, to December 31, 2020. Eligible were in hospitals the National Cancer Database; Comprehensive Network risk stratification...
Abstract Background In a recent phase III randomized control trial, delivering focal radiotherapy (RT) boost to tumors visible on MRI was shown improve disease-free survival and regional/distant metastasis-free for patients with prostate cancer—without increasing toxicity. The aim of this study assess how widely technique is being applied in current practice, as well physicians’ perceived barriers toward its implementation. Methods We invited radiation oncologists complete an online...
Optimal treatment of intermediate risk prostate cancer remains unclear. National Comprehensive Cancer Network® guidelines recommend active surveillance, prostatectomy or radiotherapy. Recent trials demonstrated no difference in specific mortality for men undergoing surveillance low compared to The use is less clear. In this study we characterize U.S. national trends demographic, clinical and socioeconomic factors associated with cancer.
This retrospective study uses data from the National Cancer Database of new cancer diagnoses across US to examine trends in proportional diagnosis rates and management patients with high-risk prostate cancer.
Abstract Purpose To develop a deep learning model to generate synthetic CT for MR‐only radiotherapy of prostate cancer patients treated with 0.35 T MRI linear accelerator. Materials and Methods A U‐NET convolutional neural network was developed translate TRUFI into electron density map using novel cost function equalizing the contribution various tissue types including fat, muscle, bone, background air in training. The impact training time, dataset size, image standardization, data...
Magnetic resonance-guided radiation therapy (MRgRT) utilization is rapidly expanding worldwide, driven by advanced capabilities including continuous intrafraction visualization, automatic triggered beam delivery, and on-table adaptive replanning (oART). Our objective was to describe patterns of 0.35Tesla(T)-MRgRT (MRIdian) in the United States (US) among early adopters this novel technology.Anonymized administrative data from all US MRIdian treatment systems were extracted for patients...
The primary objective was to compare the overall diagnostic performance, presented as detection rate of 68Ga-PSMA-HBED-CC positron emission tomography/magnetic resonance imaging (PSMA PET/MRI) versus conventional, multiparametric MRI (mpMRI) in a population patients with biochemically recurrent prostate cancer. In conjunction this analysis, secondary objectives included evaluation stratified by PSA levels and treatment modality.A total 165 PSMA PET were performed from April 2018 May 2021,...