A5080560941- Prostate Cancer Treatment and Research
- COVID-19 Clinical Research Studies
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Lymphoma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Neuroblastoma Research and Treatments
- Blood groups and transfusion
- Blood Coagulation and Thrombosis Mechanisms
- Cancer Genomics and Diagnostics
- Muscle and Compartmental Disorders
- Chronic Lymphocytic Leukemia Research
- Colorectal Cancer Treatments and Studies
- Forensic Toxicology and Drug Analysis
- Molecular Biology Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Cancer, Hypoxia, and Metabolism
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hemophilia Treatment and Research
- Blood transfusion and management
- T-cell and B-cell Immunology
- Blood properties and coagulation
Cornell University
2020-2025
LabCorp (United States)
2025
New York Hospital Queens
2020-2024
NewYork–Presbyterian Hospital
2020-2024
Presbyterian Hospital
2020-2024
Weill Cornell Medicine
2020-2023
New York Proton Center
2022
Uniformed Services University of the Health Sciences
1995
<b><i>Background:</i></b> A novel coronavirus, SARS-CoV-2, was identified in Wuhan, China late 2019. This virus rapidly spread around the world causing disease ranging from minimal symptoms to severe pneumonia, which termed coronavirus (i.e., COVID). Postmortem examination is a valuable tool for studying pathobiology of this new infection. <b><i>Methods:</i></b> We report clinicopathologic findings 32 autopsy studies conducted on patients who...
IDH1 and IDH2 mutational status is a critical biomarker with diagnostic, prognostic, treatment implications in glioma. Although p.R132H-specific immunohistochemistry available, it unable to identify other mutations IDH1/2. Next-generation sequencing can accurately determine IDH1/2 but suffers from long turnaround time when urgent planning initiation medically necessary. The Idylla assay detect unstained formalin-fixed paraffin-embedded (FFPE) slides as little few hours. In clinical...
Abstract The association of mortality with early humoral response to SARS-CoV-2 infection within the first few days after onset symptoms (DAOS) has not been thoroughly investigated partly due a lack sufficiently sensitive antibody testing methods. Here we report two and automated testing-on-a-probe (TOP) biosensor assays for viral specific total antibodies (TAb) surrogate neutralizing (SNAb), which are suitable clinical use. TOP employ an RBD-coated quartz probe using...
371 Background: SBRT is a treatment option for men with prostate cancer. PREPARE-SBRT (NCT03663218) clinical trial testing the safety of neoadjuvant MRI-guided high-risk localized We leveraged paired samples from pre-treatment biopsy (Bx) and irradiated prostatectomy (RP) specimens to evaluate immune-related transcriptomic changes in tumors at acute timepoints following SBRT. Methods: Transcriptomic profiles were generated using Decipher GRID (Veracyte, Inc). Differences transcriptional...
375 Background: Pre-Prostatectomy MRI-Guided Stereotactic Body Radiotherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT; NCT03663218) is an ongoing clinical trial testing the safety of preoperative MRI-guided SBRT men with clinically localized high-risk prostate cancer. We sought to compare transcriptomic profiles biopsy (Bx) specimens acutely irradiated radical prostatectomy (RP) specimens. Methods: Biopsy and post-irradiated RP from 10 subjects were examined. The median interval...
Abstract Inflammation perturbs evolutionary dynamics of hematopoietic stem cell (HSC) clones in clonal hematopoiesis and myeloid neoplasms. We studied HSCs, progenitors immune cells from patients with myeloproliferative neoplasm (MPN) at baseline following interferon-⍺ (IFN⍺) treatment, the only MPN therapy to deplete cells. focused on essential thrombocythemia, an informative model early-phase neoplastic hematopoiesis. integrated somatic genotyping, transcriptomes, immunophenotyping,...
[The] goal is to provide a readable account of the most common drugs abuse—what they are, how work, therapeutic uses, potential for abuse, and laboratories test them. Enough practical information included so that readers can understand interpret results drug tests. —William E. Schreiber, preface An Introduction Testing Drugs Abuse not only meets goals as stated in its but exceeds them—keeping mind book intended an “introduction” topic does claim be compendium. Undeniably, there ample...