A5090062958- COVID-19 Clinical Research Studies
- Appendicitis Diagnosis and Management
- Long-Term Effects of COVID-19
- Thyroid Cancer Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- COVID-19 diagnosis using AI
- Genetic factors in colorectal cancer
- Sarcoidosis and Beryllium Toxicity Research
- Fetal and Pediatric Neurological Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Female Genital Mutilation/Cutting Issues
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Autoimmune and Inflammatory Disorders
- Polyomavirus and related diseases
- Poxvirus research and outbreaks
- Respiratory viral infections research
- Mental Health and Patient Involvement
- Intestinal and Peritoneal Adhesions
- BRCA gene mutations in cancer
- Cancer-related molecular mechanisms research
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Food Allergy and Anaphylaxis Research
Presbyterian Hospital
2020-2024
New York Hospital Queens
2020-2024
NewYork–Presbyterian Hospital
2020-2024
Cornell University
2020-2024
Weill Cornell Medicine
2020-2021
<b><i>Background:</i></b> A novel coronavirus, SARS-CoV-2, was identified in Wuhan, China late 2019. This virus rapidly spread around the world causing disease ranging from minimal symptoms to severe pneumonia, which termed coronavirus (i.e., COVID). Postmortem examination is a valuable tool for studying pathobiology of this new infection. <b><i>Methods:</i></b> We report clinicopathologic findings 32 autopsy studies conducted on patients who...
Molecular testing (MT) of thyroid fine-needle aspiration (FNA)-derived genetic material is commonly used to assess malignancy risk for indeterminate cases. The Bethesda System Reporting Thyroid Cytopathology (TBS) provides limited guidance the appropriate use category III (atypia undetermined significance [AUS]). authors combined MT with cytomorphology monitor AUS diagnoses in a cytopathology laboratory.Neoplasia-associated alterations (NGAs) were determined by preoperative FNA biopsies or...
Tacrolimus is a common immunosuppressant used in solid organ transplant recipients. Although most patients develop diarrheal symptoms, data regarding patterns of injury taking tacrolimus are limited. We performed this study to characterize tacrolimus-related features colonic injury. retrospectively identified samples from 20 receiving monotherapy. Records were reviewed for endoscopic findings, other medications, and infections. None the had gastrointestinal infections or drugs known cause...
Data from previous studies suggest Crohn disease of the appendix accounts for ∼25% granulomatous appendicitis cases. However, we have found that inflammation in appendectomy specimens rarely heralds disease. We suspect appendiceal involvement by is uncommon, even when patients severe ileocolonic inflammation. performed this study to determine prevalence and nature among with reviewed 100 ileocolic strictures fistulizing distribution inflammatory changes compared them appendices on colectomy...
Reactivation of latent varicella zoster virus (VZV) may be limited to a dermatome or involve multiple organs, including the gastrointestinal tract. Although manifestations disseminated have been likened those herpes simplex (HSV), histologic features VZV-related injury tubular gut are not well-documented. We performed this study describe clinicopathologic injury. identified 6 such patients with VZV infection. All involved upper tract, affecting esophagus (n=3), stomach (n=2), both (n=1)....
Few cytologically indeterminate thyroid fine-needle aspirations (FNAs) harbor BRAF V600E. Here, we assess interobserver agreement for The Bethesda System Reporting Thyroid Cytopathology (TBSRTC) category III (atypia of undetermined significance [AUS]) FNAs harboring V600E and contrast their features with those non-BRAF alterations, attention to cytopathology experience.
Lymphoepithelioma-like intrahepatic cholangiocarcinoma is a rare variant of that associated with the Epstein-Barr virus. The intimate relationship between malignant epithelial cells and numerous lymphoid can make diagnosis challenging on limited tissue samples. We present 2 cases in which presence dense hematolymphoid infiltrate served to mask carcinoma initial frozen section biopsy review, respectively. bring awareness this potential diagnostic pitfall offer morphologic immunohistochemical...
Sarcoid-like granulomatosis is a known but rare adverse reaction to immune checkpoint inhibitors and chemotherapy in the treatment of advanced solid tumors. We present case 29-year-old female with pathologically confirmed poorly differentiated invasive ductal carcinoma breast presumed metastases lungs, hilar lymph nodes, liver, spleen. Despite appropriate chemotherapy, patient developed pulmonary lesions that were interpreted on imaging studies as progression malignancy. Autopsy revealed...
Patients with perforated appendicitis are often managed antibiotic therapy followed by a delayed appendectomy. Histologic features of such specimens have been incompletely described, especially in the recent literature.To describe histomorphology interval focus on that could mimic important conditions, as infections, Crohn disease, and mucinous neoplasms.Histologic evaluation 100 appendectomy clinical radiologic correlation.A total 54 patients (54%) had evidence appendiceal perforation, 97%...
Epidermoid cysts are benign of ectodermal origin that most commonly found on the face, trunk, and neck but have been infrequently described in presacral region. Presacral epidermoid seen middle-aged women to our knowledge, only two previous cases reported pediatric population. In this case report, we present a patient who underwent total mass excision with formal coccygectomy for cyst. We describe differential diagnosis clinical, radiographic, histologic work up involved obtaining correct...