A5069989224- Photochemistry and Electron Transfer Studies
- Advanced Fluorescence Microscopy Techniques
- melanin and skin pigmentation
- Receptor Mechanisms and Signaling
- Photoreceptor and optogenetics research
- Foreign Language Teaching Methods
- Photochromic and Fluorescence Chemistry
- Trypanosoma species research and implications
- Nanoplatforms for cancer theranostics
- Computational Drug Discovery Methods
- Bacterial biofilms and quorum sensing
- Educational Technology in Learning
- Developmental and Educational Neuropsychology
- Synthesis and Biological Evaluation
- Health and Medical Education
- Educational Technology and Assessment
- Innovative Educational Technologies
- Aging, Health, and Disability
- Molecular Junctions and Nanostructures
- Ocular Infections and Treatments
- Higher Education and Teaching Methods
- Luminescence and Fluorescent Materials
- Higher Education Teaching and Evaluation
- Educational Innovations and Challenges
- Administrative Law and Governance
Universidad San Pablo CEU
2024-2025
Universidad de Granada
2015-2024
Universidade Federal de São Carlos
2022
Universidade de São Paulo
2022
Instituto de Investigación Biosanitaria de Granada
2016
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
2016
Background/Objectives: Natural killer (NK) cells play a crucial role in tumor surveillance by exerting cytotoxic activity and modulating immune responses. However, tumors employ diverse evasion strategies that limit NK cell effectiveness. This review aims to explore the molecular mechanisms of activation inhibition cancer, influence microenvironment, latest advancements cell-based immunotherapies, including adoptive transfer Chimeric Antigen Receptor-Natural Killer (CAR-NK) therapies....
DPP IV, otherwise known as CD26 lymphocyte T surface antigen, is a transmembrane glycoprotein also found in circulation the blood. It plays an important role several processes like glucose metabolism and T-cell stimulation. Moreover, it overexpressed renal, colon, prostate, thyroid human carcinoma tissues. can serve diagnostic patients with lysosomal storage diseases. The biological clinical importance of having readouts for activity this enzyme, physiological disease conditions, has led us...
A new chloride-sensitive red fluorescent protein derived from Entacmaea quadricolor is described. We found that mBeRFP exhibited moderate sensitivity to chloride and, via site-directed mutagenesis (S94V and R205Y), we increased the affinity by more than an order of magnitude (kd = 106 ± 6 mM) at physiological pH. In addition, cis-trans isomerization chromophore produces a dual emission band with different sensitivities, which allowed us develop ratiometric methodology measure intracellular...
Dyes with near-red emission are of great interest because their undoubted advantages for use as probes in living cells. In-depth knowledge photophysics is essential employment such dyes. In this article, the photophysical behavior a new silicon-substituted xanthene, 7-hydroxy-5,5-dimethyl-10-(o-tolyl)dibenzo[b,e]silin-3(5H)-one (2-Me TM), was explored by means absorption, steady-state, and time-resolved fluorescence. First, near-neutral pH, ground-state acidity constant dye, pKN-A,...
M.J. Muñoz Alférez A. Lozano OrtegaB. Clares NaverosA. Conejo GarcíaO. Cruz LópezE. García FernándezR.J. Giménez MartínezM.C. González GarcíaJ.A. VeraA. Molinero GarcíaA.I. Del Moral GarcíaC. Monteagudo SánchezR. Navarrete CasasF. Ocaña PeinadoJ.M. Paredes MartínezM. Romero PérezB. Rubio RuizM.J. Ruedas RamaM. Sánchez PoloE.M. Talavera RodríguezJ. Valverde PozoR. Castilla RíosC.F. JiménezA. Martínez AvilésA. MuñozL. RoblesJ. Sepúlveda VillodresE.
M.J. Alférez A. Molinero GarcíaB. Clares NaverosA. Conejo GarcíaO. Cruz LópezE. García FernándezR.J. Giménez MartínezM.C. González GarcíaJ.A. VeraA.I. Del Moral GarcíaC. Monteagudo SánchezR. Navarrete CasasF. Ocaña PeinadoJ.M. Paredes MartínezM. Romero PérezB. Rubio RuizM.J. Ruedas RamaM. Sánchez PoloE.M. Talavera RodríguezJ. Valverde PozoR. Castilla RíosC.F. JiménezA. Lozano OrtegaA. Martínez AvilésA. MuñozL. RoblesJ. Sepúlveda VillodresE. Muñoz
This research explores the use of pepN activity fluorescent sensor DCM-Ala in bacterial biofilms, emphasizing its significance due to critical role biofilms various biological processes. Advanced imaging techniques were employed visualize activity, introducing a novel approach examining biofilm maturity. We found that overexpression increases ability
Melanoma is a type of highly malignant and metastatic skin cancer. In situ molecular imaging endogenous levels the melanoma biomarker tyrosinase (TYR) may decrease likelihood mortality. this study we proposed weakly fluorescent probe 1-(4-(2-(4-(dicyanomethylene)-4H-chromen-2-yl)vinyl)phenyl)-3-(4-hydroxybenzyl)urea (DCM-HBU), which releases strong red-shifted signal after TYR-mediated oxidation followed by hydrolysis urea linkage. The large Stokes shift dye owed to recovery intramolecular...
In this work, the spectroscopic properties of Perylene were studied in different solvents, applying Lippert equation. It has been observed that polar solvents have a more significant effect on optical Perylene.
Melanoma is a type of highly malignant and metastatic skin cancer. In situ molecular imaging endogenous levels the melanoma biomarker tyrosinase (TYR) may decrease likelihood mortality. this study, we proposed weakly fluorescent probe 1-(4-(2-(4-(dicyanomethylene)-4H-chromen-2-yl)vinyl)phenyl)-3-(4-hydroxybenzyl)urea (DCM-HBU), which releases strong red-shifted signal after TYR-mediated oxidation followed by hydrolysis urea linkage. The large Stokes shift dye owed to recovery intramolecular...
M.J.M. AlférezB. Clares NaverosA. Conejo GarcíaO. Cruz LópezE. García FernándezR.J. Giménez MartínezM.C. González GarcíaE. MuñozJ.M.. PérezJ.A. VeraA. Molinero GarcíaA.I. Del Moral GarcíaC. Monteagudo SánchezR. Navarrete CasasF. Ocaña PeinadoJ.M. Paredes MartínezM. Romero PérezB. Rubio RuizM.J. Ruedas RamaM. Sánchez PoloJ. Valverde PozoR. Castilla RíosC.F. JiménezA. Lozano OrtegaA. Martínez AvilésA. MuñozL. RoblesJ. Sepúlveda VillodresE.M. Talavera Rodríguez
M.J.M. AlférezB. Clares NaverosA. Conejo GarcíaO. Cruz LópezE. García FernándezR.J. Giménez MartínezM.C. González GarcíaJ.M. PérezJ.A. VeraA. Molinero GarcíaA.I. Del Moral GarcíaC. Monteagudo SánchezR. Navarrete CasasF. Ocaña PeinadoJ.M. Paredes MartínezM. Romero PérezB. Rubio RuizM.J. Ruedas RamaM. Sánchez PoloE.M. Talavera RodríguezJ. Valverde PozoR. Castilla RíosC.F. JiménezA. Lozano OrtegaA. Martínez AvilésA. MuñozL. RoblesJ. Sepúlveda VillodresE. Muñoz
PRELIMINARY WEB DESIGN FOR THE MANAGEMENT OF MULTIMEDIA RESOURCES IN MULTIDISCIPLINARY TEACHING TEAM FACULTY PHARMACY
TUTORIAL ACTION AND ORIENTATION FOR UNIVERSITY STUDENTS DURING THE COVID-19 PANDEMIC AT FACULTY OF PHARMACY GRANADA
A. Domínguez-Martín, M. Gómez-Guzman, J. Díaz-Castro, Moreno-Fernández, Sánchez-Santos, López-Frías, M.J.M. Alférez, López-Viota, Valverde-Pozo, Soriano-Lerma, García-Burgos, M.J. Sáez, M.E. García-Rubiño, I. López AliagaUniversity of Granada. Faculty Pharmacy (SPAIN)