- Endometrial and Cervical Cancer Treatments
- Reproductive Health and Contraception
- NF-κB Signaling Pathways
- Cell death mechanisms and regulation
- Blood Pressure and Hypertension Studies
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Testicular diseases and treatments
- Cholesterol and Lipid Metabolism
- Chronic Kidney Disease and Diabetes
- Ectopic Pregnancy Diagnosis and Management
- Ovarian cancer diagnosis and treatment
- Immune Cell Function and Interaction
- Flavonoids in Medical Research
- Atherosclerosis and Cardiovascular Diseases
- Nitric Oxide and Endothelin Effects
- Biochemical and Molecular Research
Hangzhou Normal University
2013-2022
Hebei North University
2005-2020
Nankai University
2012
Endothelial dysfunction in kidney vasculature is the initial and key element for nephropathy diabetes mellitus. Accumulating evidence suggests protective role of Rho kinase inhibitors endothelial via modulating eNOS activity NO production. However, diabetes-related relevant mechanisms remain unknown. We assessed whether pharmacological inhibition attenuates intrarenal arteries from type 1 diabetic rats. Fasudil, a inhibitor effectively decreased phosphorylated level MYPT1 without affecting...
Human epididymis protein 4 (HE4) is a novel cancer biomarker. This study evaluates the prognostic role of HE4 in determining survival endometrial patients.Literature search was conducted electronic databases (Embase, Ovid, PubMed, Scopus, and Web Science). Studies were selected if they reported relationship between patients. Random-effects meta-analyses performed to achieve estimates baseline serum levels, 5-year with high low levels/expression, hazard ratios (HRs) patients levels.9 studies...
Objective Study the clinical significance of HBX gene detection, sequence analysis in peripheral blood mononuclear cell(PBMC) chronic hepatitis B(CHB) patients with serum HBV DNA negative conversion after treatment by nucleoside analogues(NAs). Methods Detected and analyzed real time PCR PBMC 60 CHB including some cirrhosis or hepatocellular carcinoma(HCC), all had turned NAs, explore gene. Results HBX genes were detected 37 cases(61.67%, 37/60). positive rates HCC higher than...