Lihong Wang

ORCID: 0000-0001-8750-6714
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About
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Research Areas
  • Effects and risks of endocrine disrupting chemicals
  • Microplastics and Plastic Pollution
  • Toxic Organic Pollutants Impact
  • Plant Stress Responses and Tolerance
  • Liver Disease Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • RNA modifications and cancer
  • Nuclear Structure and Function
  • Per- and polyfluoroalkyl substances research
  • Autoimmune Bullous Skin Diseases
  • Mental Health Research Topics
  • Traditional Chinese Medicine Studies
  • Growth Hormone and Insulin-like Growth Factors
  • Functional Brain Connectivity Studies
  • Thyroid Disorders and Treatments
  • Nanoparticles: synthesis and applications
  • Acute Ischemic Stroke Management
  • Birth, Development, and Health
  • Hepatitis B Virus Studies
  • Dietary Effects on Health
  • Protease and Inhibitor Mechanisms
  • Prenatal Substance Exposure Effects
  • Indian History and Philosophy
  • Heme Oxygenase-1 and Carbon Monoxide
  • Aluminum toxicity and tolerance in plants and animals

Army Medical University
2023-2025

West China Medical Center of Sichuan University
2025

Gansu Provincial Center for Disease Control and Prevention
2025

Zoucheng People's Hospital
2023

Fudan University
2006-2023

Second Affiliated Hospital of Harbin Medical University
2011-2022

Harbin Medical University
2011-2022

First Affiliated Hospital of Jinan University
2021

Dali University
2020

State Key Laboratory of Food Science and Technology
2012-2019

Per- and polyfluoroalkyl substances (PFAS) are persistent ubiquitous environmental contaminants with well-documented hepatotoxicity. However, the mechanistic linkage between PFAS exposure non-alcoholic fatty liver disease (NAFLD) remains largely elusive.This study aimed to explore PFAS-to-NAFLD link relevant molecular mechanisms.The cross-sectional analyses using National Health Nutrition Examination Survey (NHANES) data were conducted investigate association NAFLD. A combination of in...

10.1016/j.envint.2023.108138 article EN cc-by-nc-nd Environment International 2023-08-01

Background— Although pharmacological studies suggest that the transient receptor potential vanilloid type 1 (TRPV1) channels expressed in sensory nerve fibers innervating heart may exert a cardioprotective effect, definitive evidence supporting such notion is lacking. In addition, function and regulation of neuropeptides, namely, calcitonin gene–related peptide (CGRP) substance P (SP), face challenges induced by cardiac injury presence or absence TRPV1 are largely unknown. Methods Results—...

10.1161/circulationaha.105.556274 article EN Circulation 2005-11-29

Summary This study retrospectively collected the clinical and laboratory data of 114 patients with Castleman disease ( CD ) from a single medical centre. Clinical classification identified 62 (54·4%) unicentric 52 (45·6%) multi‐centric disease. Pathological revealed 68 cases (59·6%) hyaline vascular variant, 16 (14·1%) mixed cellular variant (Mix) 30 (26·3%) plasmacytic variant. complications occurred in 69 patients, including 37 paraneoplastic pemphigus PNP 25 renal complications....

10.1111/bjh.13378 article EN British Journal of Haematology 2015-03-30

Bisphenol A (BPA) is an important industrial raw material. Because of its widespread use and increasing release into environment, BPA has become a new environmental pollutant. Previous studies about BPA's effects in plants focus on certain growth stage. However, the plant's response to pollutants varies at different stages. Therefore, this work, soybean roots stages were investigated by determining reactive oxygen species levels, membrane lipid fatty acid composition, peroxidation,...

10.1038/srep23782 article EN cc-by Scientific Reports 2016-03-31

Bisphenol A (BPA) is ubiquitous in the environment because of its continual application plastics and epoxy resin industry. Cadmium (Cd) a highly toxic heavy metal element mainly used smelting, electroplating, plastic dye manufacturing. Pollution as result BPA Cd exists simultaneously many agricultural regions. However, little information available regarding combined effects on plants. The photosynthesis, chlorophyll fluorescence, content soybean seedlings were investigated using noninvasive...

10.1002/etc.2720 article EN Environmental Toxicology and Chemistry 2014-08-12

To investigate alterations in resting-state spontaneous brain activity patients with major depressive disorder (MDD) experiencing multiple episodes.Between May 2007 and September 2014, 24 recurrent 22 remitted diagnosed MDD the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), 69 healthy controls matched age, sex, educational level participated this study. Among them, 1 control was excluded due to excessive head motion. The fractional amplitude of low-frequency fluctuation...

10.4088/jcp.15m10022 article EN The Journal of Clinical Psychiatry 2017-03-13

This study aims to evaluate the association of energy and macronutrient intake at dinner versus breakfast with disease-specific all-cause mortality in people diabetes.A total 4,699 diabetes who enrolled National Health Nutrition Examination Survey from 2003 2014 were recruited for this study. Energy was measured by a 24-h dietary recall. The differences (Δ) between (Δ = - breakfast) categorized into quintiles. Death information obtained Index until 2015. Cox proportional hazards regression...

10.2337/dc19-2289 article EN Diabetes Care 2020-04-30

Non-: alcoholic fatty liver disease (NAFLD) is prevalent worldwide, especially in patients with type 2 diabetes. Liver enzymes are the main warning signs of injury and insulin resistance (IR) critical to NAFLD. This study was aimed investigate association between diabetes Data from 212 NAFLD were analyzed, including 118 males 94 females who received care 2014 2015. The divided into three groups by severity (mild n=87, moderate n=89, severe n=36). All underwent standard clinical laboratory...

10.1055/a-0603-7899 article EN Hormone and Metabolic Research 2018-05-01

Abstract Bisphenol A (BPA), an emerging pollutant in the environment, has potential toxic effects on plants. The toxicity mechanism, however, remains largely unknown. antioxidant system plays important role protecting plants against damage of stress. present study investigated BPA (superoxide dismutase [SOD], peroxidase [POD], catalase [CAT], ascorbic acid [AsA], proline, reduced glutathione [GSH]), reactive oxygen species (ROS; hydrogen peroxide [H 2 O ], superoxide anion [O – ])...

10.1002/etc.2904 article EN Environmental Toxicology and Chemistry 2015-02-04

Abstract Context Nonalcoholic fatty liver disease (NAFLD) is a multisystem disease, associated with fibrosis and an increased risk of type 2 diabetes mellitus (T2DM) chronic kidney (CKD). Objective This work aimed to investigate the association NAFLD development CKD in aged patients T2DM. Methods cross-sectional study enrolled 13 915 participants. A further 1734 individuals who had been followed annually for 5 years comprised retrospective cohort study. Noninvasive markers, score (NFS),...

10.1210/clinem/dgac382 article EN The Journal of Clinical Endocrinology & Metabolism 2022-06-29

Previous studies of imaging predictors on acute treatment response in late-life depression (LLD) demonstrated that poor to selective serotonin reuptake inhibitors (SSRIs) is associated with pre-treatment low functional connectivity (FC) within executive control network and high FC default-mode including the ventromedial prefrontal cortex (vmPFC). However, there less research regional resting-state activity explains changes related SSRI response.Thirty-six older major depressive disorder...

10.1002/gps.5079 article EN International Journal of Geriatric Psychiatry 2019-02-14

Bisphenol A (BPA) is a ubiquitous chemical in the environment and potentially harmful to plants. However, relevant studies of effects BPA on plants are relatively scarce. In present work, biomass (fresh wt dry wt), absorptive function (activity area), mineral element levels soybean (Glycine max L.) seedling roots treated with 1.5 mg L(-1) , 3.0 6.0 12.0 24.0 48.0 96.0 were investigated. Treatment increased nitrate other elements (P, K, Mg, Mn, Zn, Mo) roots, whereas treatments at higher...

10.1002/etc.2770 article EN Environmental Toxicology and Chemistry 2014-10-15

Zearalenone (ZEA) is widely present in feedstuffs and raw materials, causing reproductive disorders animals.In this study, Bacillus licheniformis CK1 was used to detoxify ZEA feed for alleviating its effect Tibetan piglets.A total of 18 weaned female piglets were randomly divided into 3 groups: control group (Control, ZEA-free basal diet); treatment 1 (T1, ZEA-contaminated 2 (T2, but pre-fermented by diet).There no significant differences average daily intake (ADFI), gain (ADG), efficiency...

10.1093/jas/sky301 article EN Journal of Animal Science 2018-08-30
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