A5101859043- HIV Research and Treatment
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- vaccines and immunoinformatics approaches
- Energy, Environment, Economic Growth
- HIV/AIDS drug development and treatment
- Climate Change Policy and Economics
- RNA Interference and Gene Delivery
- Viral gastroenteritis research and epidemiology
- Cytomegalovirus and herpesvirus research
- Virus-based gene therapy research
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Respiratory viral infections research
- Monoclonal and Polyclonal Antibodies Research
- T-cell and B-cell Immunology
- Retinoids in leukemia and cellular processes
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Research and Interventions
- Fiscal Policy and Economic Growth
- Environmental Sustainability in Business
China University of Mining and Technology
2022-2024
Sun Yat-sen University
2020-2023
: A safe and effective vaccine against COVID-19 has become a public health priority. However, little is known about the willingness to accept future in China. This study aimed understand determinants for acceptance of among Chinese adults.
The HIV-1 pandemic has persisted for four decades, and poses a major challenge to global public health. Shenzhen, city with large number of migrant populations in China, is suffering epidemic. It necessary continuously conduct the molecular surveillance among newly diagnosed patients these population. In this study, plasma samples ART-naive infections were collected from Shenzhen China. partial genes gag pol amplified sequenced analysis genotype, drug resistance, transmission network....
Latent viral reservoir is recognized as the major obstacle to achieving a functional cure for HIV infection. We previously reported that arsenic trioxide (As2O3) combined with antiretroviral therapy (ART) can reactivate and delay rebound after ART interruption in chronically simian immunodeficiency virus (SIV)-infected macaques. In this study, we further investigated effect of As2O3 independent SIV-infected found As2O3-only treatment significantly increased CD4/CD8 ratio, improved...
The persistence of cells latently infected with HIV-1, named the latent reservoir, is major barrier to HIV-1 eradication, and formation maintenance reservoir might be exacerbated by activation immunoinhibitory pathway dysfunction CD8+ T during infection. Our previous findings demonstrated that prophylactic vaccination combined PD-1 blockade generated distinct immune response profiles conferred effective control highly pathogenic SIVmac239 infection in rhesus macaques. However, our surprise,...
HIV-1 CRF07_BC-p6Δ7, a strain with seven amino acid deletion in the p6 region of Gag protein, is becoming dominant HIV transmission among men who have sex (MSM) China. Previous studies demonstrated that patients infected by CRF07_BC-p6Δ7 had lower viral load and slower disease progression than those CRF07_BC wild-type strain. However, underlying mechanism for this observation not fully clarified yet. In study, we constructed recombinant DNA plasmid adenovirus type 2 (Ad2) vector-based...