A5100758014- Peroxisome Proliferator-Activated Receptors
- Fatty Acid Research and Health
- Anodic Oxide Films and Nanostructures
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Hair Growth and Disorders
- Eicosanoids and Hypertension Pharmacology
- Cancer, Lipids, and Metabolism
- HIV/AIDS drug development and treatment
- Inflammasome and immune disorders
- Adipokines, Inflammation, and Metabolic Diseases
- melanin and skin pigmentation
- Galectins and Cancer Biology
- Endometriosis Research and Treatment
- Cell Adhesion Molecules Research
- Angiogenesis and VEGF in Cancer
Sun Yat-sen University
2023
University of Louisville
2020-2022
Guangzhou Medical University
2020-2022
Guangdong Medical College
2021
Xuzhou Medical College
2020
Southeast University
2019
Abstract Obesity is associated with increased risk of many types cancer and can be induced by various high-fat diets (HFD) from different fat sources. It remains unknown whether fatty acid composition in HFD influences obesity-associated tumor development. Here we report that consumption either a cocoa butter or fish oil similar obesity mouse models. While the was accelerated mammary growth, uncoupled growth exhibited decrease protumor macrophages. Compared (FA) components both HFDs, n-3 FA...
Abstract The most recent American Dietary Guidelines (2020–2025) recommend shifting dietary fats from solid saturated to unsaturated oils. oils contain different compositions of fatty acids (UFA). Oleic acid (OA) and linoleic (LA) are the common UFA in How individual regulate immune cell function cancer risk remains unclear. Here we demonstrated that high-fat diets (HFD) rich either OA or LA induced a similar degree murine obesity, but LA-rich HFD specifically promoted mammary tumor growth....
The HIV-1 pandemic has persisted for four decades, and poses a major challenge to global public health. Shenzhen, city with large number of migrant populations in China, is suffering epidemic. It necessary continuously conduct the molecular surveillance among newly diagnosed patients these population. In this study, plasma samples ART-naive infections were collected from Shenzhen China. partial genes gag pol amplified sequenced analysis genotype, drug resistance, transmission network....
Highlights•Consumption of fish oil HFD, but not cocoa butter induces murine hair loss•TNF-α signaling in CD207− macrophages mediates HFD-induced loss•E-FABP is essential the n-3 fatty acid-induced ROS/IL-36/TNF-α axis skin macrophages•E-FABP deficiency protects mice from lossSummaryFats are healthy diets, how dietary fats affect immune cell function and overall health well understood. Mimicking human high-fat diets (HFDs), which rich different acid (FA) components, we fed various HFDs fat...
Type 2 diabetes mellitus (T2DM) is thought to be a risk factor for endometrial hyperplasia, but potential links between the two diseases are unknown. This study aims evaluate role of T2DM in progression hyperplasia.Female Sprague-Dawley rats were randomly divided into normal (N) group, hyperplasia (NH) (T) and with (TH) group. Proteomics analysis was performed determine protein profile tissues. Proliferation, migration, invasion cells with/without GLANT2-knockdown assessed....
plasmid and polyethylenimine (PEI).Sepsis was induced via cecal ligation puncture (CLP) 7 days after transfection, .RESULTS: In vitro, suppressed the production of pro-inflammatory cytokines in RAW264.7 macrophage cells lipopolysaccharide (LPS) stimulation.Of these, miR-146a displayed highest suppressive effect, wherein transcriptional activity nuclear factor kappa B (NF-jB) decreased targeting interleukin 1 receptor-associated kinase (IRAK-1) tumor necrosis 6 (TRAF6).In vivo, Treatment with...