- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Systemic Sclerosis and Related Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Health, Medicine and Society
- Myofascial pain diagnosis and treatment
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Healthcare Systems and Practices
- Orthopaedic implants and arthroplasty
- Spinal Fractures and Fixation Techniques
- Dermatologic Treatments and Research
- Clinical practice guidelines implementation
- Spondyloarthritis Studies and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging and Analysis
- Nerve Injury and Rehabilitation
- Inflammatory Myopathies and Dermatomyositis
- Pain Management and Placebo Effect
- Musculoskeletal Disorders and Rehabilitation
- Medical and Biological Sciences
- Pain Mechanisms and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Université Paris Cité
2015-2024
Hôpital Cochin
2015-2024
Assistance Publique – Hôpitaux de Paris
2015-2024
Inserm
2015-2024
Sorbonne Paris Cité
2011-2024
Toxicologie, Pharmacologie et Signalisation Cellulaire
2015-2024
Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2022-2024
Délégation Paris 5
2012-2022
Université Paris-Saclay
2022
Hôpital Raymond-Poincaré
2022
The objectives of this cross-sectional study conducted in primary care practice France were to describe general practitioners' (GPs) fear-avoidance beliefs about low back pain (LBP), investigate the impact these on their following guidelines for bed rest, physical activities, and sick leave, uncover factors associated with GPs' beliefs. A total 864 GPs completed a 5-part self-administered questionnaire. Parts 1, 2, 3 concerned demographic, professional data, personal history pain,...
In Brief Study Design. Observational prospective study. Objective. To assess the reliability, validity, and responsiveness of French version Fear Avoidance Belief Questionnaire. Summary Background Data. Fear, avoidance attitudes, belief play pivotal roles in disability perceived by patients with chronic low back pain. The Questionnaire is a two-part questionnaire assessing fear, avoidance, beliefs about professional activity physical activity. Methods. was translated use forward backward...
Non-steroidal anti-inflammatory drugs (NSAIDs) are at the cornerstone of treatment for osteoarthritis (OA). In recent years, widespread use oral NSAIDs has been called into question due to appearance significant upper gastrointestinal (GI) complications and cardiovascular (CV) adverse events (AEs). However, non-homogeneous, there noticeable differences between them in AE risk GI CV events. Nevertheless, if properly prescribed can provide an effective safe OA real-life situations. The...
The fear-avoidance beliefs of patients with subacute low back pain (LBP) considered at risk for chronic disabling LBP are not well known. objectives this cross-sectional descriptive survey, conducted in secondary care practice, were to assess about and seek an association between physician or patient characteristics level beliefs. A total 286 rheumatologists completed a self-administered questionnaire assessing physicians' demographic, professional data, personal history pain, (on the...
Abstract Objective To assess high‐sensitivity C‐reactive protein (hsCRP) level as a measure of low‐grade inflammation in relation to Modic vertebral end‐plate marrow signal change on magnetic resonance imaging (MRI) patients with chronic low back pain. Methods All hospitalized for pain our institution were prospectively enrolled this pilot study. Serum hsCRP concentration was measured by immunoturbidimetric assay. MR images evaluated independently panel 2 spine specialists and radiologist....
<h3>Introduction</h3> Imaging of heel enthesopathy in spondyloarthritis (SpA) could potentially be useful for diagnosis and monitoring. The aim this study was to assess the diagnostic capacities MRI power Doppler ultrasonography (PDUS) distinguish patients with SpA from controls between without enthesopathy. <h3>Methods</h3> A cross-sectional single-centre performed 51 (102 heels) definite according Amor9s criteria. Patients degenerative non-inflammatory low back pain (n=24, 48 were included...
Active discopathy is associated with a specific phenotype of chronic low back pain (LBP). Local inflammation has role in active discopathy-associated symptoms.To assess the efficacy single glucocorticoid intradiscal injection (GC IDI) patients LBP discopathy.Prospective, parallel-group, double-blind, randomized, controlled study. (ClinicalTrials.gov: NCT00804531).3 tertiary care centers France.135 on magnetic resonance imaging (MRI).A GC IDI (25 mg prednisolone acetate) during discography (n...
Objective To compare a physical therapy program to usual care of systemic sclerosis (SSc) patients on disability. Methods A 12‐month followup, parallel‐group randomized controlled trial involving modified Zelen design was conducted in 4 tertiary‐care hospitals. Patients were enrolled if they had disability rating ≥0.5 the Health Assessment Questionnaire index (HAQ DI) or symptoms decreased mouth opening limited range motion at least 1 joint. The experimental intervention (n = 112, which 110...
<h3>Importance</h3> Multidisciplinary prehabilitation before total knee replacement (TKR) for osteoarthritis may improve outcomes in the postoperative period. <h3>Objective</h3> To compare multidisciplinary with usual care TKR terms of functional independence and activity limitations after surgery. <h3>Design, Setting, Participants</h3> This prospective, open-label randomized clinical trial recruited participants 50 to 85 years age according American College Rheumatology criteria whom a was...
Background Resveratrol is a natural compound found in red wine. It has demonstrated anti-inflammatory properties preclinical models. We compared the effect of oral resveratrol new patented formulation to placebo for individuals with painful knee osteoarthritis. Methods and findings ARTHROL was double-blind, randomized, placebo-controlled, Phase 3 trial conducted tertiary care centers France. recruited adults who fulfilled 1986 American College Rheumatology criteria osteoarthritis reported...
Objectives. To assess the outcome of subacute low back pain, to identify characteristics patients and physicians which were related evaluate influence rheumatologists’ beliefs about pain on their following guidelines for physical occupational activity.
Objective. The present study was conducted to improve our knowledge of intervertebral disc (IVD) cell biology by comparing the phenotype nucleus pulposus (NP) and annulus fibrosus (AF) cells with that articular chondrocytes (ACs).
To identify clinical, functional and health-related quality of life (HRQoL) correlates clinically significant symptoms anxiety depression in patients with systemic sclerosis (SSc).Three-hundred-and-eighty-one fulfilling the American College Rheumatology and/or Leroy Medsger criteria for SSc were assessed visceral involvement, disability HRQoL (assessed by SF-36). Clinically evaluated Hospital Anxiety Depression Scale (HAD) (defined cut-off≥8).9.2% had limited SSc, 50.5% cutaneous (lcSSc),...
Osteopathic manipulative treatment (OMT) is frequently offered to people with nonspecific low back pain (LBP) but never compared sham OMT for reducing LBP-specific activity limitations.To compare the efficacy of standard vs limitations at 3 months in persons subacute or chronic LBP.This prospective, parallel-group, single-blind, single-center, sham-controlled randomized clinical trial recruited participants LBP from a tertiary care center France starting February 17, 2014, follow-up...