A5047508694- Musculoskeletal pain and rehabilitation
- Systemic Sclerosis and Related Diseases
- Spine and Intervertebral Disc Pathology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Osteoarthritis Treatment and Mechanisms
- Myofascial pain diagnosis and treatment
- Pain Management and Placebo Effect
- Dermatologic Treatments and Research
- Lower Extremity Biomechanics and Pathologies
- Total Knee Arthroplasty Outcomes
- Botulinum Toxin and Related Neurological Disorders
- Shoulder Injury and Treatment
- Complementary and Alternative Medicine Studies
- Clinical practice guidelines implementation
- Dermatological and Skeletal Disorders
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Immune Response and Inflammation
- Inflammatory Myopathies and Dermatomyositis
- Knee injuries and reconstruction techniques
- Transport Systems and Technology
- Autoimmune Bullous Skin Diseases
- Vascular anomalies and interventions
- Immunodeficiency and Autoimmune Disorders
- S100 Proteins and Annexins
Université Paris Cité
2019-2024
Hôpital Cochin
2018-2024
Assistance Publique – Hôpitaux de Paris
2018-2024
Inserm
2018-2024
Centre de Recherche Épidémiologie et Statistique
2018-2024
Sorbonne Paris Cité
2018-2024
Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2024
Hôtel-Dieu de Paris
2024
Délégation Paris 5
2019-2022
Target (United States)
2021
<h3>Importance</h3> Multidisciplinary prehabilitation before total knee replacement (TKR) for osteoarthritis may improve outcomes in the postoperative period. <h3>Objective</h3> To compare multidisciplinary with usual care TKR terms of functional independence and activity limitations after surgery. <h3>Design, Setting, Participants</h3> This prospective, open-label randomized clinical trial recruited participants 50 to 85 years age according American College Rheumatology criteria whom a was...
The purpose of this study was to evaluate the safety and efficacy transient genicular artery embolization (GAE) using an ethiodized oil-based emulsion for treatment knee osteoarthritis (KOA).
Osteopathic manipulative treatment (OMT) is frequently offered to people with nonspecific low back pain (LBP) but never compared sham OMT for reducing LBP-specific activity limitations.To compare the efficacy of standard vs limitations at 3 months in persons subacute or chronic LBP.This prospective, parallel-group, single-blind, single-center, sham-controlled randomized clinical trial recruited participants LBP from a tertiary care center France starting February 17, 2014, follow-up...
Background Resveratrol is a natural compound found in red wine. It has demonstrated anti-inflammatory properties preclinical models. We compared the effect of oral resveratrol new patented formulation to placebo for individuals with painful knee osteoarthritis. Methods and findings ARTHROL was double-blind, randomized, placebo-controlled, Phase 3 trial conducted tertiary care centers France. recruited adults who fulfilled 1986 American College Rheumatology criteria osteoarthritis reported...
Patient-reported outcome measures (PROMs) aimed at assessing people with systemic sclerosis (SSc) have rarely involved the target population in item- and domain-generation stage of instrument construction.To develop a new PROM activities participation SSc.A provisional International Classification Functioning, Disability Health (ICF)-based 65-item questionnaire previously developed from interviews SSc was sent by email to all patients followed internal medicine department Cochin hospital (n...
To develop an International Classification of Functioning, Disability and Health (ICF) core set for SSc to conceive a patient-centred ICF-based questionnaire assessing activities participation in patients with SSc.The construction the ICF followed two steps. In first step, meaningful concepts related were collected using data source triangulation from (n = 18), experts 10) literature 174 articles). second linked best-matching categories by one reviewer according prespecified linking rules....
<h3>Background:</h3> Osteoarthritis (OA) has long been thought to be only of local mechanical origin. However, it shown recently that there is a phenotype OA with inflammatory properties. <h3>Objectives:</h3> We hypothesize circulating neutrophils are involved in disease pathogenesis suggesting systemic involvement this "local" disease. <h3>Methods:</h3> investigated the cytosolic proteome blood from four patients an knee osteoarthritis and compared three healthy controls (HC). Functional...
<h3>Background:</h3> Interleukin-6 (IL-6) is a major inflammatory cytokine involved in pain and potentially osteoarthritis disease progression. PPV-06 an IL-6-derived peptide coupled with carrier protein, CRM197. The goal of the active immunotherapy to induce production anti-IL-6 antibodies buffer its biological activity. conjugate has been shown be safe preclinical studies. We report here results phase 1 clinical trial (First-in-human). <h3>Objectives:</h3> To assess safety, tolerability...