A5101666975- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Inflammatory mediators and NSAID effects
- Musculoskeletal pain and rehabilitation
- Rheumatoid Arthritis Research and Therapies
- Orthopaedic implants and arthroplasty
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Spine and Intervertebral Disc Pathology
- Musculoskeletal Disorders and Rehabilitation
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Systemic Sclerosis and Related Diseases
- Hip disorders and treatments
- Shoulder Injury and Treatment
- Clinical practice guidelines implementation
- Medical and Biological Sciences
- Healthcare Systems and Practices
- Cell Adhesion Molecules Research
- Hip and Femur Fractures
- Tendon Structure and Treatment
- Dermatologic Treatments and Research
- Pain Mechanisms and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Spondyloarthritis Studies and Treatments
- Delphi Technique in Research
Hôpital Cochin
2016-2025
Assistance Publique – Hôpitaux de Paris
2016-2025
Université Paris Cité
2016-2025
Inserm
2016-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2025
Université Clermont Auvergne
2025
Sorbonne Paris Cité
2013-2024
Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale
2008-2022
Institute of Rheumatology
2022
Délégation Paris 5
2012-2021
The European Society for Clinical and Economic Aspects of Osteoporosis Osteoarthritis (ESCEO) published a treatment algorithm the management knee osteoarthritis (OA) in 2014, which provides practical guidance prioritization interventions. Further analysis real-world data OA additional evidence support pharmacological interventions, terms pain function, avoidance adverse events, disease-modifying effects long-term outcomes, e.g., delay total joint replacement surgery, pharmacoeconomic factors...
<h3>Objectives</h3> To compare the effects of an intermediate molecular weight (MW) intra-articular hyaluronic acid (HA) with a low MW product on knee osteoarthritis (OA) symptoms. <h3>Methods</h3> Patients symptomatic OA were enrolled inarandomised, controlled, double-blind, parallel-group, non-inferiority trial possibility to shift superiority. randomised GO-ON(MW 800–1500 kD, 25 mg/2.5 ml) or Hyalgan(MW 500–730 20 mg/2 injected at 3-weekly intervals. The primary outcome was 6-month change...
Topical non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in international and national guidelines as an early treatment option for the symptomatic management of knee hand osteoarthritis (OA), may be used ahead oral NSAIDs due to their superior safety profile. The European Society Clinical Economic Aspects Osteoporosis Osteoarthritis (ESCEO) algorithm recommends topical OA addition pharmacological background slow-acting (SYSADOAs) rescue analgesia with paracetamol...
To assess the construct validity of Cochin Hand Function Scale (CHFS) and relevance using aggregate scores for scleroderma Health Assessment Questionnaire (sHAQ) Medical Outcomes Study 36-Item Short Form Survey (SF-36) in systemic sclerosis (SSc).We evaluated 50 patients with SSc (mean +/- SD age disease duration 54 12 years 9 8 years, respectively), which 26 had limited cutaneous (lcSSc) 23 diffuse (dSSc). Quality life was assessed by SF-36, global disability (HAQ) sHAQ, hand CHFS....
The European Society for Clinical and Economic Aspects of Osteoporosis Osteoarthritis (ESCEO) treatment algorithm recommends intra-articular (IA) hyaluronic acid (HA) management knee osteoarthritis (OA) as second-line in patients who remain symptomatic despite use non-steroidal anti-inflammatory drugs (NSAIDs). This recommendation is based upon accumulating evidence that IA HA provides a significant benefit OA. There good injections reduce pain increase function OA, the benefits are...
Background: Some guidelines recommend splinting for base-of-thumb osteoarthritis, despite lack of evidence efficacy. Objective: To assess the efficacy and acceptability a splint osteoarthritis. Design: Multicenter, randomized trial. Randomization was computer-generated, allocation concealed by faxing centralized treatment assignment to investigators at time enrollment. Patients were not blinded assignment, patients self-reported outcomes. Setting: 2 tertiary care hospitals in France....
Purpose To identify the views of patients and care providers regarding management knee osteoarthritis (OA) to reveal potential obstacles improving health strategies. Methods We performed a qualitative study based on semi-structured interviews stratified sample 81 (59 women) 29 practitioners (8 women, 11 general [GPs], 6 rheumatologists, 4 orthopedic surgeons, 8 [4 GPs] delivering alternative medicine). Results Two main domains patient were identified: one about patient–physician relationship...
Objective. To estimate the prevalence of inadequate pain relief (IPR) among patients with symptomatic knee OA prescribed analgesic therapy and to characterize IPR.
<h3>Objective:</h3> To develop and assess the reliability construct validity of a scale assessing disability involving mouth in systemic sclerosis (SSc). <h3>Methods:</h3> We generated 34-item provisional from mailed responses patients (n = 74), expert consensus 10) literature analysis. A total 71 other SSc were recruited. The test–retest was assessed using intraclass coefficient correlation divergent Spearman coefficient. Factor analysis followed by varimax rotation performed to factorial...
The purpose of this study was to evaluate the safety and efficacy transient genicular artery embolization (GAE) using an ethiodized oil-based emulsion for treatment knee osteoarthritis (KOA).