A5001993231- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Bowel Disease
- Rheumatoid Arthritis Research and Therapies
- Head and Neck Cancer Studies
- Spondyloarthritis Studies and Treatments
- Microscopic Colitis
- Chronic Disease Management Strategies
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Systemic Lupus Erythematosus Research
- Biosimilars and Bioanalytical Methods
- Autoimmune and Inflammatory Disorders Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pharmaceutical Practices and Patient Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Psoriasis: Treatment and Pathogenesis
- Maternal and fetal healthcare
- Healthcare Policy and Management
- Topic Modeling
- Cancer Diagnosis and Treatment
- Computational and Text Analysis Methods
- Maternal and Perinatal Health Interventions
- Frailty in Older Adults
- Sports injuries and prevention
Merck & Co., Inc., Rahway, NJ, USA (United States)
2016-2025
Marie Curie Hospice
2018-2023
University of Oklahoma Health Sciences Center
2022
University of Oklahoma
2018-2022
Rutgers, The State University of New Jersey
2018-2021
Indiana University – Purdue University Indianapolis
2021
Belfast Health and Social Care Trust
2019
NHS Ayrshire and Arran
2018
NHS Education for Scotland
2016
Zealand University Hospital
2016
Objective. To estimate the prevalence of inadequate pain relief (IPR) among patients with symptomatic knee OA prescribed analgesic therapy and to characterize IPR.
Background & aimsThe burden of ulcerative colitis (UC) in relation to disease severity is not well documented. This study quantitatively evaluated the relationship between activity and quality life (QoL), as health care utilization, cost, work-related impairment associated with UC an Australian population.
This study examines gender differences in post-traumatic stress symptoms (PTSS) and PTSS risk/protective factors among soldiers deployed to Iraq. We pay special attention two potentially modifiable military factors, preparedness unit cohesion, which may buffer the deleterious psychological effects of combat. Longitudinal data were collected on 922 New Jersey National Guard (91 women) Iraq 2008. Anonymous surveys administered at pre- post-deployment included PTSD Checklist (PCL), Unit Support...
Objectives: We examined rheumatologists' motivation for prescribing biosimilars, assessed their treatment preferences in relation to behavior and explored patient attitudes biosimilars. Methods: Data were taken from the Adelphi Real World Biosimilars Programme, a real-world, cross-sectional study undertaken with German rheumatologists patients rheumatoid arthritis, ankylosing spondyloarthritis or psoriatic arthritis 2015–2016. Rheumatologists provided data on toward biosimilars invited next...
Despite well-documented postdeployment readjustment problems affecting veterans of Operations Enduring Freedom (OEF) and Iraqi (OIF), few studies have explored the possible relationship stressors to recent increase in military suicide. This study examined associations between suicidal ideation using cross-sectional population-based survey data from 1665 National Guard members who recently returned Iraq. The findings suggested that are widespread, with 45% endorsing one or more financial...
Background: Rugby union will enter the Olympic arena as Sevens in 2016. Purpose: To investigate injury rate, type, and nature of injuries sustained an amateur American rugby sevens tournament series. Study Design: Descriptive epidemiology study. Methods: The demographics, characteristics were evaluated 1536 players, from 128 sides, competing 4 1-day tournaments a USA local area union. Results: Forty-eight occurred over tournaments, for rate 55.4 per 1000 playing hours. Head neck most common...
The diagnostic process for patients presenting with cognitive decline and suspected dementia is complex. Physicians face challenges distinguishing between normal aging, mild impairment, Alzheimer's disease, other dementias. Although there some evidence improving attitudes towards the importance of prompt diagnosis, limited information describing how physicians approach this challenge in practice. This was explored present study. Across-sectional survey primary care specialist physicians, 5...
Prior studies have identified numerous barriers to the prompt diagnosis of patients with suspected Alzheimer's disease (AD). The aim study was evaluate physician's perceptions importance previously diagnosis, but a specific focus on presentation mild cognitive impairment (MCI), which may be indicative neurodegenerative disorders such as AD. A second how perspective primary care physicians (PCPs) differ from that specialists. cross-sectional online survey PCPs and specialists who routinely...
This study examined gastroenterologists' motivation for prescribing biosimilars, assessed their treatment preferences in relation to behaviour, and explored patient attitudes biosimilars.Data were taken from the Adelphi Real World Biosimilars Programme, a real-world, cross-sectional undertaken 2015-2016 with German gastroenterologists patients ulcerative colitis or Crohn's disease. Gastroenterologists provided data on behaviour towards invited next eight eligible consecutive consulting...
Current information is scarce regarding comorbid conditions, treatment, survival, institutionalization, and health care utilization for Alzheimer's disease (AD) patients.Compare all-cause mortality, rate of economic burden between treated untreated newly-diagnosed AD patients.Patients aged 65-100 years with ≥1 primary or ≥2 secondary diagnoses (ICD-9-CM:331.0] continuous medical pharmacy benefits ≥12 months pre-index ≥6 post-index date (first diagnosis date) were identified from Medicare...
The objective of this study was to evaluate long-term health-related quality life outcomes among patients who had a colectomy within the previous 10 years. A cross-sectional survey administered consecutive ≥18 years age with ulcerative colitis last from centers in Canada, Australia, and United Kingdom. Data were extracted medical chart reviews confirm selected self-reported patient characteristics. Of 351 respondents, 49 % male median 40 (interquartile range 30–52). Respondents diagnosed UC...
Ensuring effective identification and management of sepsis is a healthcare priority in many countries. Recommendations for primary care have been produced, but complex systems, an in-depth understanding current system interactions functioning often essential before improvement interventions can be successfully designed implemented. A structured participatory design approach to model was employed hypothesise gaps between work as intended delivered inform implementation priorities...
Background: A long-term horizon is necessary when the socioeconomic consequences and potential effects of interventions in Alzheimer’s disease (AD) are estimated. Objectives: To illustrate societal costs AD across continuum to cost-effectiveness a hypothetical intervention with modifying treatment (DMT). Methods: Based on Swedish dementia registry, Markov model was used simulate virtual cohort 100,000 people mild cognitive impairment (MCI) due (AD-MCI) Sweden for 40 years starting at age 60....
The programmed death-1 (PD-1) immune checkpoint inhibitor pembrolizumab is currently approved in the US for first-line (1L) treatment of recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), either alone combination with platinum 5-fluorouracil (5-FU). However, toxicity 5-FU has motivated study alternate combinations that replace a taxane. objective current was to describe baseline characteristics, patterns sequences, real-world outcomes individuals receiving + taxane as...
Background/Objectives To analyse the relationship between caregiver burden and severity of patients’ cognitive impairment. Design Data were drawn from cross-sectional 2015/2016 Adelphi Real World Dementia Disease-Specific Programme. Setting This research was multi-national studied physicians their consulting patients with Participants 1,201 caregivers completed self-assessment forms. Measurements Validated instruments wellbeing (EQ-5D-3L questionnaire, EQ-VAS, Zarit Burden Interview, Work...
To describe the real-world use of adalimumab for maintenance treatment ulcerative colitis (UC) and associated healthcare costs in English hospitals.Retrospective cohort study.Analysis NHS Hospital Episode Statistics linked with pharmacy dispensing data hospitals.Adult UC patients receiving ≥240mg during induction, subsequently maintained on adalimumab.Frequency pattern dose escalation (prescriptions hospital visits).191 completed induction. 83 (43.46%) escalated by ≥100% (equivalent to...
In the US, growing demand for precision medicine, particularly in oncology, continues to put pressure on availability of genetic counselors meet that demand. This is especially true certain geographic locations due uneven distribution throughout US. To assess these disparities, access all specialties explored by geography, cancer type, and social determinants health. Geospatial technology was used combine analyze counselor incidence at county level across with a particular focus tumors...