A5002678057- Renal Diseases and Glomerulopathies
- Collembola Taxonomy and Ecology Studies
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Hemiptera Insect Studies
- Gastrointestinal disorders and treatments
- Neuroendocrine Tumor Research Advances
- Metastasis and carcinoma case studies
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Colorectal and Anal Carcinomas
- Immunodeficiency and Autoimmune Disorders
- Medical Imaging and Pathology Studies
- Lung Cancer Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Surgical Treatments
- Autoimmune Bullous Skin Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Electrolyte and hormonal disorders
- Nephrotoxicity and Medicinal Plants
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pharmacological Effects of Natural Compounds
Kumamoto University
2011-2024
Port and Airport Research Institute
2023
Kobe Children's Hospital
2020
Kobe University
2020
Akita Industrial Technology Center
2016-2020
Creative Research Enterprises (United States)
2017
Niigata University
1981-2017
Niigata University Medical and Dental Hospital
2017
Niigata Cancer Center Hospital
2017
Kyoto University
2015
The endoscopic Congo red test combined with dyeing methylene blue was performed in 85 patients early gastric cancer (94 lesions). Results revealed that bleached the and sprayed over their surface this appeared sharp contrast to red-colored mucosa of unaffected areas. Grossly, polypoid flat types, histologically differentiated adenocarcinomas dyes more frequently intensely than depressed undifferentiated adenocarcinomas. Thus spread cancerous growth could be judged rather accurately so target...
The purpose of these studies was to investigate the effects melatonin on production steroids (progesterone, testosterone, and estradiol) cAMP by preovulatory follicles examine changes in concentrations ovary during estrous cycle. Adult cyclic hamsters were used this study. Melatonin ovary, pineal gland, serum measured at mid-light mid-dark Effects steroidogenesis follicles, thecae, granulosa cells examined, its effect also investigated. (0.1-10 ng/ml) had no steroid absence hCG, but...
A survey of untoward reactions, especially central nervous system after the administration a newly introduced measles, mumps and rubella (MMR) vaccine in Gunma Prefecture, Japan, was initiated soon 4 patients were hospitalized for aseptic meningitis. Thirty-five, 6 2 children developed meningitis, convulsive disorders parotitis, respectively, within months MMR vaccination during 8-month period extending from April to November, 1989. The time lag between meningitis ranged 14 28 days 35 cases...
The values of the cytologic features individual cells and cellular patterns in aspirated materials diagnosis 49 hepatocellular carcinomas (HCC) were investigated. Excellent specimens obtained by percutaneous aspiration biopsy with a heparinized fine 22-gauge needle. In well-differentiated type HCC, correct malignancy was difficult from because their resemblance to normal hepatocytes. contrast, moderately differentiated poorly types easily made cells, but there little or no evidence hepatic...
The cytologic picture of small cell carcinoma primarily arising from the esophagus was studied with 7 cases which were confirmed by histologic examination. Cytomorphologic characteristics are as follows: arrangement groups tumor cells is irregular and overlapping indistinct boundaries. cytoplasm small, or sometimes absent. nuclei round, oval occasionally spindle shaped. Nuclear borders thin. chromatin finely granular pattern has increased evenly distributed.
A procedure was developed for obtaining both cytologic and histologic specimens from patients suspected of having hepatic malignancy at the time ultrasonically guided liver aspiration biopsy using a 22-gauge needle 0.4 mm inner diameter. The fine syringe used were heparinized before use to avoid blood coagulation in materials obtained. With it possible centrifuge obtained make good smears containing abundant tumor cells, obtain small tissue specimens. Histologic with fixed 2.5%...
Hamartomatous polyps in the stomach have been described as gastric lesions of familial polyposis coli.Four cases multiple hamartomatous not associated with coli were encountered.Histologically, all these consisted normal oxyntic glands numerous cystic dilatations glandular lumens various sizes.Endoscopically, located acid secreting area and had an function, which was revealed by endoscopic Congo red test.Cnncer 45818-823.1980. HERE HAVE BEEN MANY reports about gastricT co1i.1s~24~23Two main...
The levels of carcinoembyronic antigen (CEA) in the serum and gastric juice 58 patients with cancer were determined by radioimmunoassay. level CEA was not a satisfactory indicator cancer: it elevated only 19.4% cases advanced unresectable 4.5% early examined. However, significantly higher than normal subjects or benign diseases: increased concentrations outputs observed 54.5% 40.1%, respectively, cancer, 52.9% 50.0%, cancer. gross type had no influence on level, but tended to be high when...
Diagnostic accuracy of the cytologic examination or CEA measurement in pancreatic fluid obtained by percutaneous fine-needle aspiration biopsy under ultrasonic guidance, was investigated 26 patients with histologically proven carcinoma pancreas, and incidence positive results cytology assay were compared endoscopic cannulation ampulla Vater same 19 patients. Positive findings observed 88.5% carcinoma. The location cancer had no influence on cytology, but more frequent distant metastases than...
The effects of gastrin on the histopathology glandular stomach and incidence gastric carcinoma induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) were investigated in inbred Wistar (W) rats. Prolonged administration after treatment with MNNG significantly reduced adenocarcinomas stomach. In addition, atypical proliferations less frequent smaller, marked mucosal atrophy was both antral oxyntic gland mucosae. Both hyperplasia are precursors cancers; prolonged to rats suppressed development...
Percutaneous aspiration biopsy of the pancreas using a heparinized 22-gauge fine needle was performed under ultrasonic guidance in five patients with benign pancreatic diseases and 18 cancer. Using syringe, it possible to make good smears containing abundant tumor cells obtain small tissue specimens. egg albumin as binding material, new cell-block technic developed conveniently histologic In this way, correct diagnosis made cytologically all 23 suspected having malignancy. Histologic...
The relation of gastric acid-secreting function to the gross and histological types locations carcinomas was examined in 53 patients with early carcinomas. Studies were made by endoscopic Congo red test developed this clinic. Results indicated a close correlation between carcinoma extent area. In general, when area large, ulcerated histologically undifferentiated, they chiefly located nonacid-secreting areas adjacent areas, or sometimes surrounded areas. On contrary, there little no polypoid...
In order to find the characteristics of gastric cancer cell, tissues from 23 patients and benign mucosae 16 were observed both with light electron microscopes. cell a mucus containing sac was observed, which tentativel named intracellular microcyst. Light microscopically microcyst is as vacuole confirmed on serial sections provided microvilli its internal surface, surrounded by filaments. Microcyst had characteristic structure in undifferentiated gastic cell. It never found normal mucosa or...
The distribution of intestinal metaplasia in relation to the acid-secreting are was investigated 66 patients not suffering from gastroduodenal diseases. Studies were made via endoscopic Congo Red test combination with methylene blue staining method. In this test, area is identified as a "discolored" which turns red blue-black, and areas observed methylen blue. A close relationship found between metaplasia; general, tended be more extensive frequent when small. It also that increased age....
The diagnostic accuracies of measurement carcinoembryonic antigen (CEA) and analysis the cytologic characters pure pancreatic juice were assessed in 16 control subjects, 20 patients with pancreatitis 22 cancer. Pure was collected from duct by endoscopic cannulation using a duodenofiberscope after intravenous administration secretin. fluid centrifuged supernatant used for CEA assay, while cell pellet examined cytologically. Abnormally high levels significantly more frequent cancer; an...
AIMTo assess the clinical significance of prophylactic lateral pelvic lymph node dissection (LPLND) in stage Ⅳ low rectal cancer. METHODSWe selected 71 consecutive cancer patients who underwent primary tumor resection, and enrolled 50 these without LPLN metastasis.The had distant metastasis such as liver, lung, peritoneum, paraaortic LN.Clinical was defined LN with a maximum diameter
Key clinical message Pseudohypoaldosteronism (PHA) carries a good prognosis if treated early and appropriately, but some cases can have life‐threatening events. We underscored the need to consider secondary PHA as one of differential diagnoses hyponatremia hyperkalemia in infancy. Abstract type 1 has two classifications; primary type, caused by genetic abnormalities that develop during neonatal infancy periods, urinary tract malformation infection. Secondary PHA, prognosis; however, present...