A5101974793- Neurogenetic and Muscular Disorders Research
- Bone health and treatments
- Acute Myeloid Leukemia Research
- Peripheral Nerve Disorders
- Glutathione Transferases and Polymorphisms
- Muscle metabolism and nutrition
- Fatty Acid Research and Health
- Gastrointestinal Bleeding Diagnosis and Treatment
- Aquatic life and conservation
- Retinoids in leukemia and cellular processes
- Genomics, phytochemicals, and oxidative stress
- PI3K/AKT/mTOR signaling in cancer
- Vitamin D Research Studies
- Psychosomatic Disorders and Their Treatments
- Epigenetics and DNA Methylation
- Protein Degradation and Inhibitors
- Silymarin and Mushroom Poisoning
- Eosinophilic Disorders and Syndromes
- Cardiac pacing and defibrillation studies
- Redox biology and oxidative stress
- Voice and Speech Disorders
- Gastrointestinal disorders and treatments
- Muscle Physiology and Disorders
- Sports Performance and Training
- Phytochemical and Pharmacological Studies
Mansoura University
2010-2024
Armed Forces Hospital
2024
University of Tabuk
2024
Saint Joseph Hospital
2024
Delta University for Science and Technology
2024
Cairo University
2022-2023
Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein modulating versican/platelet derived growth factor (PDGF) axis HCC.HCC was experimentally induced male Sprague-Dawley rats then treated 25 or 75 mg/kg genistein. Antioxidant activities assessed by measuring the gene expression Nrf2 hepatic levels malondialdehyde (MDA), superoxide dismutase (SOD) reduced...
Background and objectives Hepatocellular carcinoma (HCC) is a highly aggressive malignant tumor with poor prognosis. It currently the second most common cause of cancer-related mortality. Arctiin, compound found in plants commonly used as vegetable Asian countries an ingredient traditional European dishes, possesses various properties, including anti-proliferative, anti-senescence, anti-oxidative, anti-tumor, toxic, anti-adipogenic, anti-bacterial effects. Our study aims to investigate...
Fucoidan is sulfated polysaccharide of brown seaweed. It offers various pharmacological actions like anti-inflammatory, anti-bacterial and anti-tumor activities. Therefore, we aimed to investigate the effect targeting microRNA-143 inflammatory pathway by on experimentally induced hepatocellular carcinoma (HCC) in rats. HCC Sprague Dawley thioacetamide. Rats were treated with 100 mg/kg 200 Fucoidan. Hepatic sections stained hematoxylin/esosin for investigation cell integrity. Moreover,...
Acute myeloid leukemia (AML) shows multiple chromosomal translocations & point mutations which can be used to refine risk-adapted therapy in AML patients. Ecotropic viral integration site-1 (EVI-1) myocyte enhancer factor 2 C gene (MEF2C) are key regulatory transcription factors hematopoiesis and leukemogenesis both drive immune escape. This prospective study involved 80 adult de novo patients recruited from Oncology Center, Mansoura University, between March 2019 July 2021. The MEF2C EVI1...
The current trial investigates the impacts of replacing fish meal (FM) with corn gluten (CGM) on tilapia fish's productive performance and economic efficacy. A 12-week feeding experiment was conducted to examine impact substituting FM CGM 360 fingerlings Nile (with initial weight = 3.01 ± 0.01 g). experimental were randomly divided into six equal groups, triplicates in each group (20 per replicate). control administered FM-based diets (CGM0) 20% FM. Whereas, employed substitute 20%, 40%,...
Diverticular bleeding is the leading cause of lower gastrointestinal bleeding, affecting 3-5% patients with diverticulosis. Current management protocols include resuscitation, diagnosis via direct visualization, computed tomography imaging, endoscopic interventions, angioembolization, and surgery when needed. However, predictive factors for outcomes optimal interventions remain ambiguous.
Abstract To compare the efficacy and safety between trabeculectomy (TE) canaloplasty (CP) either as standalone or combined with phacoemulsification (PTE PCP). Nine databases were searched for studies reporting of TE/PTE CP/PCP. Efficacy endpoints included postoperative intraocular pressure (IOP), complete, qualified success, while failure, revision surgery, complications. STATA was used to pool crude mean difference (MD) log odds ratio (logOR) continuous categorical outcomes, respectively....
Abstract Background Acute myeloid leukemia (AML) with advancing age represents a therapeutic challenge. The tools used for comprehensive geriatric assessment (CGA) in elderly AML are not uniform. Methods This is retrospective study that included 226 patients (≥60 years), identified from the electronic database and followed till end of 2021. Comorbidities were assessed using Charlson Comorbidity Index (CCI), Cumulative Illness Rating Scale-Geriatric (CIRS-G), Hematopoietic cell...
Breast cancer is the most prevalent diagnosed malignancy among women worldwide [1]. It also major cause of malignancy-related death [2]. In Egypt, breast commo...