Abstract Extracts from five Antarctic lichens (L3, Stereocaulon alpinum ; L5, Ramalina terebrata L6, Caloplaca sp.; L8, Lecanora and L17, regalis ) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentration (MIC) of each extract was determined a broth dilution method. L3, L6 L8 active two Gram(+) strains. B. subtilis more sensitive to lichen extracts (except L5) than S. aureus . MIC observed 36.7 ± 0.3 953.8...

Abstract Background Several plants are reported to be produced various biological active compounds. Lichens from the extreme environments such as high altitude, UV, drought and cold believed synthesized unique types of secondary metabolites than other one. human pathogenic bacteria fungi have been muted into drug resistant strains. Various synthetic antioxidant compounds posed carcinogenic effects. This phenomenon needs further research for new effective drugs natural origin. manuscript...

Piper longum L. is a tropical and subtropical medicinal plant that has been used as antidiabetic, diarrhea, stomachache, cough, asthma, bronchitis since ancient times. The in vitro-grown callus from the leaf, however, not tested utilized for any of these conditions. Thus, this research pursues to assess comparative study antioxidant, antibacterial, antidiabetic activities various parts longum-grown wild. antioxidant activity crude extracts fractions were determined by DPPH...

The development of new antibacterial compounds is an urgent issue to meet the evolution resistivity pathogenic bacteria against available drugs. objective this study was investigate from Antarctic lichen species Ramalina terebrata. A total fi ve compounds, usnic acid, usimine A, B, C, and ramalin, were isolated by bioactivity guided-fractionation methanol extract R. terebrata after several chromatographic procedures. qualitative activities crude determined disk diffusion method while minimum...

Several lichen species are reported to be used tradiationally in many theraupatic practices. Many as sources of several bioactive natural compounds. Nepal so far chemically unexplored.

A total of twenty four lichen species belonging to six families were collected from mountainous region Nepal.The methanol extracts each tested for antimicrobial and antioxidant activities in vitro.It was found that one active against B. subtilis seven S. aureus.Similarly, DPPH assay, three Peltigera sp., Cladonia Canoparmelia sp.showed comparable activity with commercial standard, BHA.In ABTS + Parmoterma Ramalina sp. stronger than ascorbic acid.The observed data after comparison previously...

Streptomyces species are prolific sources of bioactive secondary metabolites known especially for their antimicrobial and anticancer activities.This study sought to isolate characterize antioxidant molecules biosynthesized by sp. KTM18. The potential an isolated compound its toxicity were accessed.The was purified using bioassay-guided chromatography techniques. Nuclear magnetic resonance (NMR) experiments carried out structure elucidation. the determined DPPH free radical scavenging assay....

Abstract Antioxidant agents counter reactive oxygen species (ROS) and can be used in cosmetic medicinal applications. The goal of this study was to evaluate the antioxidant activity an Antarctic moss from King George Island (Antarctica), tentatively designated as KSJ‐M5. On basis morphological characteristics, KSJ‐M5 identified Sanionia uncinata (Hedw.) Loeske (Amblystegiaceae). identification confirmed by comparing partial sequence ITS (internal transcribed spacer) region with that GenBank....

Antioxidant agents against reactive oxygen species can be used for several cosmetic and medicinal applications. This study’s objective was to evaluate the antioxidant activities of Polytrichastrum alpinum (Hedw.) G. L. Sm. (Polytrichaceae), an Antarctic moss collected from King George Island (Antarctica). The identifi cation performed on basis morphological characteristics molecular sequencing 18S rRNA gene. Two benzonaphthoxanthenones: ohioensins F G, were isolated extract after...

Plants have a pivotal role in ethnopharmacology, and their preparations are use globally. However, getting down to the structure requires an effective workflow mostly time-consuming isolation process. Although bioassay-guided approaches widely popular, they face massive problem of rediscovery recent times, especially plant metabolomics. Mass spectrometry (MS)-based approach incorporated molecular networking via Global Natural Product Social Molecular Networking (GNPS) is considered here for...

Fats and phthalic acid derivatives were isolated characterised based on their spectral analysis from the antifouling activity guided fractions of n-hexane methanol extract brown alga Sargassum confusum. The fractions, as well compounds, demonstrated significant against spores a major fouling Ulva pertusa with 50–75% decrease spore attachment agar-coated slides.

Paris polyphylla Sm. is a vulnerable medicinal plant employed in the treatment of various ailments. This study seeks to establish protocol for callus induction, proliferation, and differentiation P. polyphylla. Immature leaf explants were cultured on MS medium with varying concentrations growth regulators (PGRs), including 2,4-dichlorophenoxyacetic acid (2,4-D), kinetin (Kn), 6-benzylaminopurine (BAP), Thidiazuron (TDZ), α-Naphthalene acetic (NAA), Gibberellic (GA3), along 10% coconut water....

This study was done to compare the pre and post-operative hearing results in patients undergoingcanal wall down mastoidectomy with classical type III tympanoplasty using temporalis fasciaalone.Patients of ≥5 years age diagnosis Chronic otitis media (squamous) conductive ormixed loss, needing canal intact mobile stapessuprastructure at surgery who underwent were included thestudy. The PTA performed evaluated. hearingwas assessed terms average ABG size closure.Mean air bone gap 37.8 dB 29.8dB...

Two compounds, compounds 1 and 2, were isolated from Preussia sp. The molecular structures of both elucidated by analyzing one-dimensional (1D) 2D nuclear magnetic resonance data along with high-resolution mass spectrometry data. Compound was obtained as novel in structure, compound 2 recently reported elsewhere. did not show antioxidant antimicrobial activities brine shrimp toxicity, while showed strong activity (DPPH reduction capacity; IC50=3 μg/mL) toxicity (LD50=50 μg/mL).

To assess, analyze and compare the results of graft uptake using Tragal Cartilage-Perichondrium Composite (TCPC) with Temporalis Fascia (TF) in patients who undergoing surgery for chronic otitis media - squamous type. Patients aged 13 years above diagnosis type modified radical mastoidectomy, either primary or revision grafting tympanic membrane (TM) excision postero-superior retraction pocket (PSRP) were included this study. divided two groups: Group A-patients TCPC B -patients TF graft....

Background: This study aimed to document the traditional knowledge of people in Khumbu Valley within Sagarmatha National Park and Buffer Zone Nepal regarding utilization harvesting practices Himalayan medicinal plant Neopicrorhiza scrophulariiflora, which is under threat due over-harvesting. Methods: The used focus group discussions key informant interviews gather ethnobotanical from residents seven enclave settlements park buffer zone. These were later grouped into three village clusters...