A5101456631- Phytochemistry and Biological Activities
- Phytochemical and Pharmacological Studies
- Fungal Biology and Applications
- Traditional Chinese Medicine Analysis
- Powdery Mildew Fungal Diseases
- Medicinal Plant Pharmacodynamics Research
- Traditional Chinese Medicine Studies
- Nanoplatforms for cancer theranostics
- Botanical Studies and Applications
- Lung Cancer Treatments and Mutations
- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- MRI in cancer diagnosis
- Plant and animal studies
- Cancer-related Molecular Pathways
- Immune cells in cancer
- Respiratory viral infections research
- Drilling and Well Engineering
- Venous Thromboembolism Diagnosis and Management
- Extracellular vesicles in disease
- Natural product bioactivities and synthesis
- Genetic diversity and population structure
- Hydraulic Fracturing and Reservoir Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Botany, Ecology, and Taxonomy Studies
Chongqing Academy of Chinese Materia Medica
1991-2024
Union Hospital
2021-2022
Jilin University
2020-2022
China Academy of Chinese Medical Sciences
2016-2021
Union Hospital
2020
Peng Huanwu Center for Fundamental Theory
2006
Institute of Chinese Materia Medica
1991-2002
Microwave-assisted extraction was applied to extract rutin; quercetin; genistein; kaempferol; and isorhamnetin from Flos Sophorae Immaturus. Six independent variables; namely; solvent type; particle size; frequency; liquid-to-solid ratio; microwave power; time were examined. Response surface methodology using a central composite design employed optimize experimental conditions (liquid-to-solid time) based on the results of single factor tests five major components in Experimental data fitted...
Abstract Coptis chinensis Franch, a perennial herb, is mainly distributed in southeastern China. The rhizome of C. has been used as traditional medicine for more than 2000 years China and many other Asian countries. pharmacological activities have validated by research. Here, we present de novo high-quality genome with chromosome-level ~958.20 Mb, contig N50 1.58 scaffold 4.53 Mb. We found that the relatively large size was caused amplification long terminal repeat (LTR) retrotransposons. In...
Photodynamic therapy (PDT) is an effective therapeutic modality that has been extensively studied in treatment of various cancers. However, issues with inadequate oxygen (O2) concentration tumor tissue and immune response generation have hindered its successful application therapy.Firstly, the self-assembly nanocomplex (CAT-Ce6), which composed hydrophilic catalase hydrophobic photosensitizer Chlorin e6 (Ce6), was fabricated to support oxygenated PDT. Secondly, for supplying PDT enhanced...
, the main source of traditional Chinese medicine Lonicerae Flos, is extensively cultivated in Southwest China. However, quality
Realizing that the potential of photodynamic therapy (PDT) is hindered by hypoxic microenvironment tumor section, it desirable to provide a cascade oxygenation strategy enhance PDT.The hydrophilic catalase protein was covalently linked hydrophobic photosensitizer Ce6 form nanocomplex Catalase-Ce6 with self-assembly. And loaded in M1 macrophage vesicles (EVs) GOX-modified construct nanosystem Catalase-Ce6@MEVs. The synergistic effects PDT induced Catalase-Ce6@MEVs were evaluated on...
To explore the genetic diversity and relationship of different Scrophularia ningpoensis cultivars.Forty-eight germplasmic resources S. cultivars were analyzed by Start Codon Targeted Polymorphism(SCOT) molecular markers. Genetic distance was calculated TREECONW software systematic diagram clustered UPGMA method.A total 279 bands detected using 48 primers, among which 214 polymorphic bands. The average percentage 76.7%. changed from 0.1507 to 0.4933. Clustering results showed that more...
To investigate the profile of gene function and search for SSR, a new technology high-throughput Solexa/Illumina sequencing was used to generate root transcriptome Scrophularia ningpoensis, 65 602 036 raw reads were obtained. Based on bioinformatics analysis Trinity, 73 983 unigenes obtained with an average length 823 bp. The comparison sequence homology in database showed that 56 389 had different degrees homology. A total 520 metabolic pathways related genes 191 relDODO transcription...
Root rot disease restricts the Coptis chinensis industry in Shizhu of Sichuan province. To disclose fungi composition and pathogen root,so as to prevent treat root disease,the C. 5 years from 4 areas were collected 3 seasons respectively. The isolated molecularly morphological identified,followed with population statistics. 437 isolated,belonging subphylum,11 classes,16 orders,22 families 28 genus There are great difference among compositions different area,year sampling season,while there...
To investigate the genetic diversity among wild Dipsacus asperoides in China, 66 germplasmic resources of D. were analyzed by Start Codon Targeted Polymorphism (SCoT) molecular markers. Genetic distance was calculated TREECONW software and systematic diagram relationship clustered UPGMA method. The results showed that totals 181 bands detected using 20 primers , which 109 polymorphic bands. average percentage 60.13%. changed from 0.030 6 to 0.181 4. clustering there no significant...
To establish a sensitive and specific HPLC method for quality control of Codonopsis tangshen.The samples were determined with the dereloped method. By Similarity Evaluation System Chromatographic Fingerprint Traditional Chinese Medicine (Version 2004A), mean chromatogram was generated as representative standard fingerprint similarity each against also calculated. Samples clustered using principal component analysis (PCA) based on ratio characteristic peaks peak. The chromatographic...
Objective To investigate the different clinical characteristics of minimally invasive transforaminal lumbar interbody fusion on treatment spondylolisthesis combined with severe narrowing intervertebral space or simple grade II spondylolisthesis. Methods Thirty-eight patients were divided into groups A (16 cases narrowing) B (22 without narrowing). Differences in preoperative preparation, operation time, blood loss, tool selection, decompression, reduction, pedicle screw, cage size and other...