A5012624841- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Diet and metabolism studies
- Obesity and Health Practices
- Surgical site infection prevention
- Nutrition, Genetics, and Disease
- Cardiovascular Health and Risk Factors
- Diabetes and associated disorders
- Bariatric Surgery and Outcomes
- Health and Lifestyle Studies
- Health and Wellbeing Research
- Metabolism, Diabetes, and Cancer
- Health and Conflict Studies
- Antibiotic Use and Resistance
- Biological Research and Disease Studies
- Antibiotic Resistance in Bacteria
- Metabolomics and Mass Spectrometry Studies
- Maternal and Perinatal Health Interventions
- Medical Malpractice and Liability Issues
- Nutrition, Health and Food Behavior
- Global Maternal and Child Health
- Traditional Chinese Medicine Studies
Partners In Health
2020-2025
National Institutes of Health
2023
University of Kigali
2023
National Institute of Diabetes and Digestive and Kidney Diseases
2023
University of Global Health Equity
2023
Brigham and Women's Hospital
2020
University of Rwanda
2020
Introduction The paucity of data on perioperative outcomes in low- and middle-income countries complicates the design implementation targeted interventions to improve delivery safe, affordable, accessible timely surgical anaesthesia care services. We assessed patients undergoing at three Rwandan rural hospitals—Butaro District Hospital, Kirehe Hospital Rwinkwavu Hospital—supported by Partners In Health/Inshuti Mu Buzima—an international non-governmental organisation. Methods conducted a...
<strong>Background:</strong> As the volume of surgical cases in low- and middle-income countries (LMICs) increases, surgical-site infections (SSIs) are becoming more prevalent with anecdotal evidence antimicrobial resistance (AMR), despite a paucity data on patterns. <strong>Objectives:</strong> primary objective, this prospective study aimed to describe epidemiology SSIs associated AMR among women who delivered by cesarean at rural Rwandan hospital. secondary objectives, also assessed...
Antimicrobial resistance (AMR) is a global public health threat. Worse still, there paucity of data from low- and middle-income countries to inform rational antibiotic use.
Abstract Background To eliminate hepatitis C, Rwanda is conducting national mass screenings and providing to people with chronic C free access Direct Acting Antivirals (DAAs). Until 2020, prescribers trained authorized initiate DAA treatment were based at district hospitals, DAAs remains expensive geographically difficult for rural patients. We implemented a mobile clinic provide initiation primary-level health facilities among identified through screening campaigns in Kirehe Kayonza...
Background: Women in low-resource settings will likely develop late surgical site infections (SSIs), diagnosed after post-operative day (POD) 10. We measured SSI prevalence and predictors of persistent SSIs-suggestive symptoms among women who delivered via cesarean section (c-section). Patients Methods: underwent c-sections at Kirehe District Hospital (KDH) between September 2019 February 2020 were prospectively enrolled. Data collected on POD1, POD11, POD30. Logistic regression identified...
Objective: To improve detection of abnormal glucose tolerance (Abnl-GT), attention has moved beyond the oral test (OGTT), to non-fasting markers glycemia, specifically, HbA1c, fructosamine (FA) and glycated albumin (GA). Emerging data suggest that in African descent populations, combination HbA1c GA is superior FA. However, diagnosis Abnl-GT usually based on tests which are performed only once. As reproducibility by (GA) unknown, FA were assessed 209 African-born Blacks living America....
Curative direct-acting antiviral treatment (DAA) has made it plausible to implement hepatitis C elimination interventions. However, poor knowledge among patients could impede the effectiveness of screening and programs. We assessed on rural Rwandans initiating DAA for in a prospective cohort. administered 15 true-false statements before initiation during one follow-up visit occurring either 1 or 2 months after initiation. average number correct responses per patient, proportion individual...
Abstract Background : To eliminate hepatitis C, Rwanda is conducting national mass screenings and providing C patients with free access to Direct Acting Antivirals (DAAs). Until 2020, all prescribers trained authorized initiate DAA treatment were based at District Hospitals, DAAs remains expensive geographically difficult for rural patients. We designed implemented a mobile clinic provide initiation primary-level health facilities among identified through screening campaigns in Kirehe...
Background: In African populations, attitudes towards both optimal body size and healthful weights are evolving. Due to the adverse effect of obesity on health, larger sizes beginning be seen as less ideal. Our goal was determine satisfaction in immigrants who were obese. Methods: The participants 326 African-born Blacks enrolled Africans America cohort living metropolitan Washington DC (female: 39%, age 40±11y (mean±SD). region origin were: West: 49% (161/326), Central 12% (39/326) East:...
Introduction: Sub-Saharan Africa has the highest percentage of people in world living with diabetes who are undiagnosed. To avoid end-organ damage, identification undiagnosed needs prioritization. Glucola (75g glucose) used for oral glucose tolerance test (OGTT) is expensive and rarely available sub-Saharan Africa. Due to hemoglobinopathies, G6PD deficiency, challenges associated fasting, both A1C fasting plasma (FPG) may be diagnostically unreliable. As an alternative OGTT, we developed...
A1C represents glycated hemoglobin A and is a non-fasting measure of average glycemia which has been used since 2010 to diagnose abnormal glucose tolerance (Abnl-GT) (a summary term for diabetes prediabetes). However, may not correlate with in the presence anemia, G6PD deficiency certain hemoglobinopathies. Two markers have proposed as alternatives are fructosamine (FA) albumin (GA). FA all plasma proteins. Whereas GA subfraction FA. Emerging data suggests that diagnosis Abnl-GT, superior...
As the insulin assay is expensive and often unavailable in low income countries, triglyceride-glucose index (TyG) undergoing global evaluation as both a surrogate marker of resistance (IR) predictor cardiovascular disease (CVD). Yet value TyG African-born populations uncertain. Therefore, 555 Blacks currently living Washington, DC area (Age: 39±0.4y (mean±SE), Male: 65% (358/555), BMI: 27.7±0.2 kg/m2) we determined: 1) ability to predict presence IR; 2) correlations between four lipid...
Achieving early diagnosis of type 2 diabetes (T2D) in Africans is challenging. The Glucola used the OGTT expensive and unavailable most African countries. Alternatives to are fasting plasma glucose (FPG) A1C, but they have a low diagnostic sensitivity Africans. As an alternative (75g glucose) OGTT, we developed Pastry Sugar Tolerance Test (PSTT) with pastry sugar powder) dissolved hot water. inexpensive widely available Africa. Hence, our aim was determine agreement between (1) PSTT; (2)...
In African immigrants, the relationship between obesity and body size dissatisfaction cardiometabolic health is unknown. Hence, we assessed in 352 African-born Blacks living Washington DC area (female: 39% (137/352) age 40±11y (mean±SD)). Using Stunkard Figure Rating Scale, participants ranked their perceived wish size. Body was defined as difference Adverse determined by presence of type 2 diabetes (T2D) or elevated BP (BP≥120/80) non-HDL cholesterol levels. Obesity prevalence 27% (94/352)...