A5089300525- Global Maternal and Child Health
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Global Health and Surgery
- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Global Health Workforce Issues
- COVID-19 and healthcare impacts
- Trauma and Emergency Care Studies
- Diversity and Career in Medicine
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Policy and Management
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- HIV-related health complications and treatments
- Healthcare Systems and Technology
- Emergency and Acute Care Studies
- Birth, Development, and Health
- Reproductive System and Pregnancy
- Enhanced Recovery After Surgery
- HIV Research and Treatment
- Gestational Diabetes Research and Management
- Child Nutrition and Water Access
- Migration, Health and Trauma
- HIV/AIDS Research and Interventions
Massachusetts General Hospital
2016-2025
Harvard University
2016-2025
Center for Global Health
2017-2024
Boston University
2022-2024
Mbarara University of Science and Technology
2021-2023
University of North Carolina at Chapel Hill
2023
Massachusetts Medical Society
2023
Social Change and Development
2021
Community Link
2020
University of Alberta
2019
Biological data are lacking with respect to risk of vertical transmission and mechanisms fetoplacental protection in maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.To quantify SARS-CoV-2 viral load neonatal biofluids, transplacental passage anti-SARS-CoV-2 antibody, incidence infection.This cohort study was conducted among pregnant women presenting for care at 3 tertiary centers Boston, Massachusetts. Women reverse transcription-polymerase chain reaction...
<h3>Abstract</h3> <h3>Objective</h3> To provide an update on economic related inequalities in caesarean section rates within countries. <h3>Design</h3> Secondary analysis of demographic and health surveys multiple indicator cluster surveys. <h3>Setting</h3> 72 low middle income countries with a survey conducted between 2010 2014 for the latest situation inequality, 28 also 2000 2004 change inequality over time. <h3>Participants</h3> Women aged 15-49 years live birth during two or three...
SARS-CoV-2 infection causes more severe disease in pregnant women compared to age-matched non-pregnant women. Whether maternal changes the transfer of immunity infants remains unclear. Maternal infections have previously been associated with compromised placental antibody transfer, but mechanism underlying this is not established. Here, we used systems serology characterize Fc profile influenza-, pertussis-, and SARS-CoV-2-specific antibodies transferred across placenta. Influenza-...
To describe the clinical presentation, symptomology, and disease course of coronavirus 2019 (COVID-19) in pregnancy.The PRIORITY (Pregnancy CoRonavIrus Outcomes RegIsTrY) study is an ongoing nationwide prospective cohort people United States who are pregnant or up to 6 weeks postpregnancy with known suspected severe acute respiratory syndrome 2 (SARS-CoV-2) infection. We analyzed presentation COVID-19 participants tested positive for SARS-CoV-2 infection reported symptoms at time testing.Of...
Introduction Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking. Methods We performed a cohort study 4,231 Ugandan women presenting to regional referral hospital for delivery or postpartum care, measured vital signs after delivery, structured physical exam, symptom questionnaire, microbiologic evaluation febrile hypothermic women. Malaria rapid diagnostic testing, blood urine cultures were...
There is a paucity of recent prospective data on the incidence postpartum infections and associated risk factors in sub-Saharan Africa. Retrospective studies estimate that puerperal sepsis causes approximately 10% maternal deaths Africa.We enrolled 4231 women presenting to Ugandan regional referral hospital for delivery or care into cohort measured vital signs postpartum. Women developing fever (> 38.0 °C) hypothermia (< 36.0 underwent symptom questionnaire, structured physical exam, malaria...
Coloniality in global health manifests as systemic inequalities, not based on merit, that benefit one group at the expense of another. Global surgery seeks to advance equity by inserting into agenda; however, it inherits biases health. As a diverse practitioners, we aimed examine inequities surgery. Using structured, iterative, Delphi consensus-building process drawing literature and our lived experiences, identified five categories non-merit inequalities These include Western epistemology,...
Understanding alumni satisfaction and the competencies gained during university training can guide improvements in education quality, particularly higher institutions. This study at Mbarara University of Science Technology (MUST) explored factors influencing decisions, their residency experiences, levels satisfaction. Additionally, it provided recommendations for improving graduate programs. We conducted a mixed methods from June to September 2022, employing an online survey in-depth...
Introduction: Normal pregnancy is associated with cardiovascular changes that enable adaptation to the state. We sought describe haemodynamic from prepregnancy very early in women planning conceive southwestern Uganda. Methods: In this prospective cohort study, we enrolled Uganda conceive. Brachial and central blood pressure, heart rate, cardiac output, stroke volume, peripheral vascular resistance were assessed repeated pregnancy. Results: studied 86 a mean age of 27.8 years (SD ± 4.4). The...
Introduction Hypertensive disorders of pregnancy (HDP) are a leading cause global perinatal (fetal and neonatal) maternal morbidity mortality. We sought to describe HDP determine the magnitude risk factors for adverse outcomes among women with in southwestern Uganda. Methods prospectively enrolled pregnant admitted delivery diagnosed at tertiary referral hospital Uganda from January 2019 November 2019, excluding pre-existing hypertension. The participants were observed documented. used...
Maternal anemia is a significant risk factor for maternal morbidity and mortality, increasing of preterm birth, intrauterine growth restriction, stillbirth, death. Moderate severe in pregnancy defined as hemoglobin (Hb) <10 g/dl Hb < 7 g/dl, respectively. We aimed to characterize the association with maternal, neonatal, placental outcomes resource-limited setting.Data were collected from prospective cohort 352 pregnant women at tertiary academic Ugandan hospital. One hundred seventy-six...
In Uganda, an estimated 120 obstetrician/gynecologists serve a population of 30 million people demonstrating the need to train additional skilled clinician leaders in reproductive health. 2012, partnership was formed with Mbarara Regional Referral Hospital (MRRH) southwest Uganda and Massachusetts General (MGH) Boston, USA, part increase access specialist training. This report presents update development teaching conference between institutions.In June didactic teleconference institutions...
To test the functionality and acceptability of a wireless vital sign monitor in an inpatient obstetric unit.Pregnant women at U.S. tertiary-care hospital wore sensor that captures heart rate, respiratory temperature. Measurements were compared with signs obtained by standard devices. We defined continuous capture for 30 min data transfer to central as functional success. Acceptability was assessed per pregnant nurses observing device. Bland-Altman plots constructed assess agreement between...
Introduction Preterm neonatal mortality contributes substantially to the high globally. In Uganda, preterm accounts for 31% of all deaths. Previous studies have shown variability in rates by healthcare setting. Also, different predictors influence risk populations. Understanding low-resource setting where we conducted our study could guide development interventions improve outcomes neonates. We thus aimed determine incidence and among neonates born at Mbarara Regional Referral Hospital...
Abstract Background Women with previous cesarean deliveries, have a heightened risk of poor maternal and perinatal outcomes, associated short interbirth intervals. We determined the prevalence interval, factors, among women antecedent deliveries who delivered at Mbarara Regional Referral Hospital (MRRH), in southwestern Uganda. Methods conducted cross-sectional study on postnatal ward MRRH from November 2020 to February 2021. enrolled had through consecutive sampling. obtained participants’...
Graduate tracer studies provide an avenue for assessing the impact of residency training on distribution and access to specialty care exploring job professional satisfaction alumnus. This study examined how Mbarara University Science Technology (MUST) clinical program influenced spatial career paths specialists. We conducted a mixed methods involving online survey 12 in-depth interviews (IDIs) from June September 2022. The was distributed convenient sample alumnus MUST via email Whatsapp...
We tested functionality and acceptability of a wireless fetal monitoring prototype technology in pregnant women an inpatient labor unit the United States. Women with full-term singleton pregnancies no evidence active were asked to wear for 30 minutes. assessed by evaluating ability successfully monitor heartbeat minutes, transmit this data Cloud storage view on web portal. Three obstetricians also rated cardiotocographs ease readability. administering closed open-ended questions perceived...
Introduction . The proportion of women with severe maternal morbidity from obstructed labor is between 2 and 12% in resource-limited settings. Maternal vaginal colonization group B streptococcus (GBS), Escherichia coli , Enterococcus spp. associated neonatal morbidity. It unknown if these organisms poor outcomes. Objectives To determine whether GBS, E. or increased among to the risk factors for antibiotic susceptibility patterns. Methods We screened all presenting Uganda’s Mbarara Regional...
Over 3 million stillbirths occur annually in sub Saharan Africa; most intrapartum and are largely preventable. The standard of care for fetal heart rate (FHR) assessment sub-Saharan African settings is a Pinard Stethoscope, limiting observation to one person, at point time. We aimed test the functionality acceptability wireless FHR monitor that could allow expanded monitoring capacity rural Southwestern Uganda. In mixed method prospective study, we enrolled 1) non-laboring healthy term...
Comprehensive HIV treatment and care makes it safer for women living with (WLWH) to have the children they desire, partly through provision appropriate use of effective contraception. However, nearly one third WLWH in-care in a large Ugandan cohort became pregnant within 3 years initiating ART half these incident pregnancies (45%) were unplanned. We therefore describe future pregnancy plans associated factors among postpartum rural southwestern Uganda order inform interventions promoting...