Cyprien Shyirambere

ORCID: 0000-0002-3203-3873
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About
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Research Areas
  • Global Cancer Incidence and Screening
  • Economic and Financial Impacts of Cancer
  • Cervical Cancer and HPV Research
  • Advances in Oncology and Radiotherapy
  • Colorectal Cancer Screening and Detection
  • AI in cancer detection
  • Health Systems, Economic Evaluations, Quality of Life
  • Global Health and Surgery
  • Acute Lymphoblastic Leukemia research
  • COVID-19 and healthcare impacts
  • Childhood Cancer Survivors' Quality of Life
  • Breast Lesions and Carcinomas
  • Global Maternal and Child Health
  • Ethics and Legal Issues in Pediatric Healthcare
  • Cancer Genomics and Diagnostics
  • Hepatitis B Virus Studies
  • Renal and related cancers
  • Chronic Myeloid Leukemia Treatments
  • Travel-related health issues
  • Malaria Research and Control
  • Viral-associated cancers and disorders
  • Advanced Radiotherapy Techniques
  • Viral Infections and Outbreaks Research
  • Patient-Provider Communication in Healthcare
  • Neutropenia and Cancer Infections

Partners In Health
2016-2025

Clinical Research Management
2022

University Teaching Hospital of Butare
2011-2021

HealthPartners
2021

Brigham and Women's Hospital
2018

Ministry of Health
2016-2018

Harvard University
2018

Abramson Cancer Center
2018

Rwanda Biomedical Center
2018

Muhimbili University of Health and Allied Sciences
2017

Abstract Background Butaro Cancer Center of Excellence (BCCOE) was founded to serve Rwanda’s rural low-income population, providing subsidized cancer diagnosis and treatment with transport stipends for the lowest-income patients. We examined whether travel distance BCCOE associated advanced-stage diagnoses completion. Methods conducted a retrospective cohort study using medical record data from patients pathologically-confirmed breast 2012–2016. Women no prior surgery were included in stage...

10.1186/s12885-025-13489-2 article EN cc-by BMC Cancer 2025-01-27

Background Giardia duodenalis is highly endemic in East Africa but its effects on child health, particularly of submicroscopic infections, i.e., those below the threshold microscopy, and genetic subgroups (assemblages), are not well understood. We aimed at addressing these questions examining epidemiological characteristics G. southern highland Rwanda. Methodology/Principal Findings In 583 children <5 years age from communities health facilities, intestinal parasites were assessed by...

10.1371/journal.pntd.0001677 article EN cc-by PLoS neglected tropical diseases 2012-06-12

Increased control has produced remarkable reductions of malaria in some parts sub-Saharan Africa, including Rwanda. In the southern highlands, near district capital Butare (altitude, 1,768 m), a combined community-and facility-based survey on Plasmodium infection was conducted early 2010.A total 749 children below five years age were examined 545 randomly selected from 24 villages, 103 attending health centre charge, and 101 at referral hospital. Clinical, parasitological, haematological,...

10.1186/1475-2875-10-134 article EN cc-by Malaria Journal 2011-05-18

Abstract Background Large scale physical distancing measures and movement restrictions imposed to contain COVID-19, often referred as ‘ lockdowns ’, abruptly ubiquitously restricted access routine healthcare services. This study describes reported barriers coping mechanisms accessing among chronic care patients during the nationwide COVID-19 lockdown in Rwanda. Methods cross-sectional was conducted enrolled pediatric development, HIV/AIDS, non-communicable diseases, mental health, oncology...

10.1186/s12889-021-10783-z article EN cc-by BMC Public Health 2021-04-10

Cancer services are inaccessible in many low-income countries, and few published examples describe oncology programs within the public sector. In 2011, Rwanda Ministry of Health (RMOH) established Butaro Center Excellence (BCCOE) to expand cancer nationally. hopes informing care delivery similar settings, we program-level experience implementing BCCOE, patient characteristics, challenges encountered.Butaro was founded on diverse partnerships that emphasize capacity building. Services...

10.1186/s12885-016-2256-7 article EN cc-by BMC Cancer 2016-03-18

Introduction The paucity of data on perioperative outcomes in low- and middle-income countries complicates the design implementation targeted interventions to improve delivery safe, affordable, accessible timely surgical anaesthesia care services. We assessed patients undergoing at three Rwandan rural hospitals—Butaro District Hospital, Kirehe Hospital Rwinkwavu Hospital—supported by Partners In Health/Inshuti Mu Buzima—an international non-governmental organisation. Methods conducted a...

10.1136/bmjgh-2024-017354 article EN cc-by-nc-nd BMJ Global Health 2025-03-01

Rwanda is a densely populated low-income country in East Africa. Previously considered failed state after the genocide against Tutsi 1994, has seen remarkable growth over past 2 decades. Health care predominantly delivered through public hospitals and emerging private sector. More than 80% of patients are covered by community-based health insurance (Mutuelle de Santé). The cancer unit at Biomedical Center (a branch Ministry Health) responsible for setting implementing policy. made progress...

10.1200/go.20.00281 article EN cc-by-nc-nd JCO Global Oncology 2020-07-23

Feasible and effective strategies are needed to facilitate earlier diagnosis of breast cancer in low-income countries. The goal this study was examine the impact health worker training on care utilization, patient diagnoses, stage a rural Rwandan district.We conducted cluster randomized trial intervention at 12 19 centers (HCs) Burera District, Rwanda, 2 phases. We evaluated trainings' volume visits for concerns using difference-in-difference models. used generalized estimating equations...

10.1200/jgo.19.00209 article EN cc-by-nc-nd Journal of Global Oncology 2019-11-27

Depression is often co-morbid with chronic conditions, and when combined HIV it can increase progression reduce survival. A brief accurate screening tool for depression among children living necessary to access mental health care improve HIV-related outcomes in the long-term. validation study was conducted, comparing Children's Inventory (CDI) a structured clinical assessment as gold standard ages 7-14 years Rwanda. The response rate 87 % analysis performed 100 participants. Twenty-five...

10.1186/s12887-016-0565-2 article EN cc-by BMC Pediatrics 2016-02-22

Abstract Background Moral distress and burnout are highly prevalent among oncology clinicians. Research is needed to better understand how resource constraints systemic inequalities contribute moral in order develop effective mitigation strategies. Oncology providers low- middle-income countries well positioned provide insight into the experience of cancer care priority setting expertise guide solutions. Methods Semistructured interviews were conducted with a purposive sample 22 physicians,...

10.1002/onco.13818 article EN cc-by-nc-nd The Oncologist 2021-05-10

Geographic access to care is an important measure of health equity. In this study, we describe geographic cancer centers (CCCs) in Rwanda with the current facilities providing and examine how could change expanded infrastructure. Health included are public hospitals administered by Ministry Health. The WorldPop Project was used estimate population distribution, OpenStreetMap determine travel routes. On basis geolocations facilities, AccessMod 5 percentage that live within 1 hour, 2 hours, 4...

10.1200/go.21.00395 article EN cc-by-nc-nd JCO Global Oncology 2022-05-01

Improvements in childhood survival rates have been achieved low- and middle- income countries that made a commitment to improve access cancer care. Accurate data on the costs of delivering treatment these settings will allow ministries health donors accurately assess plan for expansions This study assessed financial cost treating two common pediatric cancers, nephroblastoma Hodgkin lymphoma, at Butaro Cancer Center Excellence rural Rwanda.

10.1200/jgo.17.00155 article EN cc-by-nc-nd Journal of Global Oncology 2018-11-15

Most cervical cancer cases and deaths occur in low- middle-income countries, yet clinical research from these contexts is significantly underrepresented. We aimed to describe the treatment quality, resource-driven adaptations, outcomes of patients Rwanda. A retrospective cohort study was conducted all with newly diagnosed enrolled between April 2016 June 2018. Data were abstracted medical records analyzed using descriptive statistics, Kaplan Meier methods, Cox proportional hazards...

10.1016/j.ygyno.2021.12.002 article EN cc-by Gynecologic Oncology 2021-12-14

Success in treating nephroblastoma high-income countries has been transferred to some resource-constrained settings; multicenter studies report disease-free survival of greater than 70%. However, few reports present care models with rural-based components, tasks shifted internists and pediatricians, data collection structured for monitoring evaluation. Here, we clinical outcomes protocol compliance patients evaluated at Butaro Cancer Center Excellence Rwanda.This retrospective study the 53...

10.1200/jgo.2015.000067 article EN cc-by-nc-nd Journal of Global Oncology 2016-01-28

Radiotherapy is an essential component of cancer treatment, yet many countries do not have adequate capacity to serve all patients who would benefit from it. Allocation systems are needed guide patient prioritization for radiotherapy in resource-limited contexts. These should be informed by allocation principles deemed relevant stakeholders. This study explores the ethical dilemmas and views decision-makers engaged real-world scarce resources at a center Rwanda order identify principles....

10.1186/s12910-024-01005-3 article EN cc-by BMC Medical Ethics 2024-01-31

Minimal turnaround time for pathology results is crucial highest-quality patient care in all settings, especially low- and middle-income countries, where rural populations may have limited access to health care.We retrospectively determined the times (TATs) anatomic specimens, comparing three different modes of operation that occurred throughout development implementation our laboratory at Butaro Cancer Center Excellence Rwanda. Before opening this laboratory, TAT was measured months because...

10.1200/jgo.17.00081 article EN cc-by-nc-nd Journal of Global Oncology 2017-11-16

The cost of providing cancer care in low-income countries remains largely unknown, which creates a significant barrier to effective planning and resource allocation. This study examines the comprehensive at Butaro Cancer Center Excellence (BCCOE) Rwanda.A retrospective costing analysis was conducted from provider perspective by using secondary data administrative systems BCCOE. We identified start-up funds necessary begin initial implementation determined fiscal year 2013-2014 operating...

10.1200/jgo.17.00003 article EN cc-by-nc-nd Journal of Global Oncology 2017-07-17

Low- and middle-income countries account for 86% of all cervical cancer cases 88% mortality globally. Successful management requires resources that are scarce in sub-Saharan Africa, especially rural settings. Here, we describe the early clinical outcomes implementation lessons learned from Rwanda Ministry Health's first national referral center, Butaro Cancer Center Excellence (BCCOE). We hypothesize those patients presenting at earlier stage receiving treatment will have higher rates being...

10.1200/jgo.18.00120 article EN cc-by-nc-nd Journal of Global Oncology 2018-12-01

Children with acute lymphoblastic leukemia (ALL) in low-income countries have disproportionately lower cure rates than those high-income countries. At Butaro Cancer Center of Excellence (BCCOE), physicians treated patients ALL the first arm Hunger Protocol, a graduated-intensity method tailored for resource-limited settings. This article provides published outcomes, to our knowledge, this protocol.This is retrospective descriptive study enrolled at BCCOE from July 1, 2012 June 30, 2014; data...

10.1200/jgo.2017.009290 article EN cc-by-nc-nd Journal of Global Oncology 2017-10-30
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