Andréas Perren

ORCID: 0000-0001-8834-5385
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Sepsis Diagnosis and Treatment
  • Intensive Care Unit Cognitive Disorders
  • Hemodynamic Monitoring and Therapy
  • Emergency and Acute Care Studies
  • Family and Patient Care in Intensive Care Units
  • Airway Management and Intubation Techniques
  • Healthcare Decision-Making and Restraints
  • Nosocomial Infections in ICU
  • Cardiac, Anesthesia and Surgical Outcomes
  • Patient Safety and Medication Errors
  • Cardiac Arrest and Resuscitation
  • Palliative Care and End-of-Life Issues
  • Blood transfusion and management
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Anesthesia and Pain Management
  • Neonatal Respiratory Health Research
  • Muscle and Compartmental Disorders
  • Pharmaceutical Practices and Patient Outcomes
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Pharmaceutical studies and practices
  • Medical Malpractice and Liability Issues
  • Peripheral Artery Disease Management
  • Hematological disorders and diagnostics
  • Thermoregulation and physiological responses

Ospedale Regionale di Bellinzona e Valli
2013-2023

Ente Ospedaliero Cantonale
2010-2023

Ospedale Monaldi
2022

University Hospital of Zurich
2022

Università della Svizzera italiana
2019-2022

The University of Western Australia
2022

University of Geneva
2018-2022

University of Zurich
2022

Ospedale San Giovanni Bellinzona
1998-2019

Scuola Cantonale di Commercio Bellinzona
2014

Objective: older patients usually receive less invasive and costly hospital care, even if they meet the criteria for Intensive Care Unit admission or have a 'do not intubate'(DNI) order. The aim of this randomised, controlled trial was to assess effectiveness non-invasive mechanical ventilation (NIV) versus standard medical therapy (SMT) in reducing need intubation, improving survival respiratory distress very old with acute hypercapnic failure (AHRF). Participants design: eighty-two aged...

10.1093/ageing/afr003 article EN Age and Ageing 2011-02-22

To identify predictors of bacteremia in critically ill patients, to evaluate the impact blood cultures on outcome, and define conditions for breakthrough despite concurrent antibiotic treatment.A descriptive retrospective study was performed over a two-year period (2007-2008) medico-surgical Intensive Care Unit (ICU) San Giovanni Hospital Bellinzona, Switzerland.Forty-five out 231 patients (19.5%) had positive cultures. Predictors were elevated procalcitonin levels (>2 µg/L, P<0.001), higher...

10.3325/cmj.2012.53.30 article EN cc-by-nc-nd Croatian Medical Journal 2012-02-01

Adverse events (AEs) frequently occur in intensive care units (ICUs) and affect negatively patient outcomes. Targeted improvement strategies for safety are difficult to evaluate because of the intrinsic limitations reporting crude AE rates. Single interventions influence positively quality care, but a multifaceted approach has been tested only selected cases. The present study was designed rate, types, contributing factors emerging AEs test hypothesis that intervention on medication might...

10.1186/2110-5820-2-47 article EN cc-by Annals of Intensive Care 2012-11-22

This systematic review aimed to investigate the drugs used and their potential effect on noninvasive ventilation (NIV).NIV is increasingly in acute respiratory failure (ARF). Sedation analgesia are potentially beneficial NIV, but they can have a deleterious impact. Proper guidelines specifically address this issue recommendations for or against it scarce literature. In most recent published 2017 by European Respiratory Society/American Thoracic Society (ERS/ATS) relating NIV use patients...

10.5005/jp-journals-10071-23950 article EN Indian Journal of Critical Care Medicine 2022-07-30

The analysis of flow and pressure waveforms generated by ventilators can be useful in the optimization patient-ventilator interactions, notably chronic obstructive pulmonary disease (COPD) patients. To date, however, a real clinical benefit this approach has not been proven. aim present randomized, multi-centric, controlled study was to compare optimized ventilation, driven waveforms, standard ventilation (same physician, same initial ventilator setting, time spent at bedside while screen...

10.1186/cc10567 article EN cc-by Critical Care 2011-01-01

Limited information exists in regard to drug omissions and unjustified medications the hospital discharge summary (DS).To evaluate incidence types of DS, assess their potential impact on patient health.A prospective observational review DSs all patients discharged from our Internal Medicine Department over a 3-month period. Data assessment was made by internists using structured form.Of 577 evaluated DSs, 66% contained at least one inconsistency accounting for total 1012 irregularities....

10.1136/qshc.2007.024588 article EN BMJ Quality & Safety 2009-05-24

Introduction: Breast surgery is associated with persistent postsurgical pain; usually related to poorly treated acute pain. Paravertebral block has been successfully employed in analgesic protocols for breast surgery; its impact on postdischarge pain (PDP) not investigated. The aim of this study was assess characteristics PDP after surgery, the development chronic postoperative (CPP) and health care costs. Methods: We conducted a retrospective, observational continuous cohort adult female...

10.2147/jpr.s195702 article EN cc-by Journal of Pain Research 2019-04-01

Objectives: The influence of different forms treatment limitation on mortality rate in the ICU is not known despite common use latter as a quality indicator. aim present study was to assess prevalence and its rate. Primary outcomes were severity-adjusted Secondary included association with age, sex, type admission, diagnostic group, intensity, length stay. Design: Retrospective, observational study. Setting: All Swiss adult ICUs. Interventions: None. Patients: A total 166,764 patients...

10.1097/ccm.0000000000004658 article EN Critical Care Medicine 2020-10-07

There is no gold standard to assess data quality in large medical registries. Data auditing may be impeded by protection regulations.To explore the applicability and usefulness of funnel plots as a novel tool for control critical care registries.The Swiss ICU-Registry from all 77 certified adult ICUs (2014 2015) was subjected assessment (completeness/accuracy). For analysis accuracy, list logical rules cross-checks developed. Type number errors (true coding or implausible data) were...

10.1093/intqhc/mzy249 article EN International Journal for Quality in Health Care 2018-12-14

PRINCIPLES: The nine equivalents of nursing manpower use score (NEMS) is frequently used to quantify, evaluate and allocate workload at intensive care unit level. In Switzerland it has also become a key component in defining the degree ICU hospital reimbursement. accuracy nurse registered NEMS scores real life was assessed error-prone variables were identified. METHODS: this retrospective multicentre audit three reviewers (1 nurse, 2 intensivists) independently reassessed total 529 scores....

10.4414/smw.2012.13555 article EN cc-by Schweizerische medizinische Wochenschrift 2012-04-05

Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of registered untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement sum-scores/variables among between nurses reviewers' gold standard were assessed globally for tertiles. Bland Altman (gold standard-nurses) sum regression difference determined. A...

10.1155/2012/919106 article EN cc-by Critical Care Research and Practice 2012-01-01
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